Results 191 to 200 of about 4,547,937 (252)

Metrnl: A Novel Therapeutic Target in Atherosclerosis

iNew Medicine, EarlyView.
ABSTRACT Atherosclerosis is a chronic inflammatory vascular disease and the main pathological basis of cardiovascular and cerebrovascular events. Exploration of endogenous protective factors in the disease is beneficial for the establishment of new therapeutic strategies.
Pin Wang, Dao‐Xin Wang, Chao‐Yu Miao
wiley   +1 more source

Fine-tuning immunity: ubiquitin-dependent regulation of interleukin-17A expression by Th17 cells. [PDF]

Front Immunol
Raj D, Verma AK, Mathur R, Woody J, Kathania M, Venuprasad K.   +5 more
europepmc   +1 more source

High‐Sugar Diet and Intestinal Diseases: A Shared Microbiota–Barrier–Immunity–Metabolism Axis in Inflammatory Bowel Disease, Food Allergy, and Colorectal Cancer

iNew Medicine, EarlyView.
ABSTRACT The global incidence of intestinal diseases—including food allergy, inflammatory bowel disease (IBD), and colorectal cancer (CRC)—continues to escalate in parallel with the expansion of the “Western diet,” within which the high‐sugar diet (HSD) has emerged as a pivotal yet under‐recognized dietary driver.
Yuchen Wang, Yajuan Wu, Huayang Sheng, Shouhong Jiang, Jinping Cheng, Ye Kuang, Miao Liu, Lei Feng, Yanan Sun, Jinzhi Duan   +9 more
wiley   +1 more source

β-Glucan pretreatment activates lectin pathway to maintain the function of intestinal Th17 cells for infectious enteritis protection. [PDF]

Zool Res
Zhao Y, Mei X, Yang J, Wang Z, Liu Q, Zhang Y, Yang D.   +6 more
europepmc   +1 more source

Analysis of individualized brain–gut association networks and transcriptional patterns in major depressive disorder

Interdisciplinary Medicine, EarlyView.
Individualized brain–gut association networks suggest potential neuropathological mechanisms in MDD and MDDSI. Multilevel brain–gut association changes involving HSV‐1 and inflammation may be relevant to MDD, whereas alterations related to insulin metabolism may play a potential role in the neuropathological mechanisms of MDDSI.
Wei Wang, Baoyuan Zhu, Yuanyuan Huang, Liqin Liang, Zhaobo Li, Yunheng Diao, Minxin Guo, Heng Zhang, Jing Zhou, Fengchun Wu, Kai Wu   +10 more
wiley   +1 more source

The Quinazoline Derivative, QNZ, Alleviates Experimental Autoimmune Encephalomyelitis by Suppressing Th1 and Th17 Cells. [PDF]

CNS Neurosci Ther
Yang F, Yang Y, Zhang G, Li J, Chen S, Zhou Y, Kong Y, Luo X, Liu Y, Xu Y, Wang Y.   +10 more
europepmc   +1 more source

Toll‐Like Receptors in the Mechanism of Hexabromocyclododecane‐Induced Production of Pro‐Inflammatory Cytokines

Journal of Applied Toxicology, EarlyView.
ABSTRACT Hexabromocyclododecane (HBCD), a brominated flame retardant, has raised increasing health concerns due to its bioaccumulation in human tissues and its ability to induce proinflammatory cytokines. Interleukin‐1β (IL‐1β), interleukin‐6 (IL‐6), and tumor necrosis factor‐α (TNF‐α) are major mediators of inflammation, and their chronic elevation ...
Wenjun Zhu, Aleshia Seaton‐Terry, Brian Townsend, Zinia Hunter, April Falconer‐Turner, Syeda Raika Shahid, Margaret Whalen   +6 more
wiley   +1 more source

Commentary: Increased circulating Th17 cells and altered CD4 T cell maturation and differentiation in active tuberculosis with type 2 diabetes: a pilot study. [PDF]

Front Immunol
Mutavhatsindi H, Shey M.
europepmc   +1 more source

Adaptive Immunity in Marsupials

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
Comparison of the marsupial and eutherian adaptive immune systems. ABSTRACT Marsupials diverged from eutherian mammals 125–160 million years ago. Although evolutionarily distinct, both groups of mammals can produce complex adaptive immune responses to antigens with several key differences.
Cassandra L. Jol, Hayley J. Stannard, Julie M. Old   +2 more
wiley   +1 more source

Low Th17 cells in patients with cystic fibrosis and allergic broncho-pulmonary aspergillosis. [PDF]

Pediatr Allergy Immunol
Timpano S, Bellicini I, Poli P, Moratto D, Cortesi M, Salvi M, Chiarini M, Padoan R, Pezzotta R, Fiorentini S, Caruso A, Giacomelli M, Badolato R.   +12 more
europepmc   +1 more source