Results 201 to 210 of about 127,043 (265)

ATP/P2X7 receptor signal aggravates ischemic stroke injury by activating Th17 cells via STAT3/IL-21 pathway. [PDF]

Front Immunol
Liu W, Li D, Zhang M, Yin J, Wang P, Liu P, Song Z, Ni B, Peng Y.   +8 more
europepmc   +1 more source

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

Med Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng, Junjie Chen, Rui Fu, Jiawei Zhang, Jianguang Jia, Wei Wang, Zheng Zhang, Peng Zhang, Haosong Chen, Huake Cao, Gang Li, Weiwei Sheng, Ting Li, Bo Chen, Guodong Cao   +14 more
wiley   +1 more source

Fungal pathogen-responsive Th17 cells in gut-mouth axis enhance protection against oropharyngeal candidiasis. [PDF]

iScience
Kaji E, Nagao JI, Kishikawa S, Toyonaga K, Tasaki S, Iwai S, Nakagami M, Iwanuma A, Ikeda M, Tanaka Y.   +9 more
europepmc   +1 more source

Cytokine Profiles in Myasthenia Gravis Subgroups and the Lack of Any Effect of Immunosuppression

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Myasthenia gravis (MG) is a clinically and immunologically heterogeneous autoimmune disease and there is little known about the differential effects of cytokines in disease subgroups. This study aimed to compare serum cytokine profiles across distinct MG subgroups, including early‐onset MG (EOMG), late‐onset MG (LOMG), muscle‐
Merve Cebi, Hacer Durmus, Arman Çakar, Mehmet Güven Günver, Yesim Parman, Feza Deymeer, Güher Saruhan‐Direskeneli   +6 more
wiley   +1 more source

Endoscopic healing in pediatric IBD perpetuates a persistent signature defined by Th17 cells with molecular and microbial drivers of disease. [PDF]

Cell Rep Med
Siebert K, Faro T, Köhler N, Hölz H, Jarosch S, Matchado M, Häcker D, De Zen F, Hajji MS, Lurz E, Koletzko S, Pauling JK, Steiger K, Neuhaus K, Ohnmacht C, List M, Busch DH, Haller D, Schwerd T.   +18 more
europepmc   +1 more source

Painful Bilateral Necrosis of the Scalp

JEADV Clinical Practice, EarlyView.
Zoé Dumesnil, Manuel Croix, Anael Dumont, Kottler Diane, Mohamed‐Taha Tagmouti, Anne Dompmartin, Jean‐Matthieu L'Orphelin   +6 more
wiley   +1 more source

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

Portal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao, Sheng Cheng, Qiaoling Pan, Jiong Yu, Hongcui Cao   +4 more
wiley   +1 more source

GPR55 Antagonist CID16020046 Suppresses Collagen-Induced Rheumatoid Arthritis by Suppressing Th1/Th17 Cells in Mice. [PDF]

Int J Mol Sci
Lee JE, Im DS.
europepmc   +1 more source

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux, Nieves Velez de Mendizabal, Aksana Jones, Scott Balsitis, Stephan Schmidt, Justin S. Feigelman, Francine Johansson Azeredo   +6 more
wiley   +1 more source

Th9 and Th17 Cells in Human Ulcerative Colitis-Associated Dysplastic Lesions. [PDF]

Clin Med Insights Oncol
Cui G, Yuan A, Sørbye SW, Florholmen J.
europepmc   +1 more source