Results 201 to 210 of about 197,134 (290)

Successful Use of Bimekizumab in Refractory Acute Generalised Exanthematous Pustulosis Triggered by Amoxicillin‐Clavulanate

JEADV Clinical Practice, EarlyView.
ABSTRACT Acute generalised exanthematous pustulosis (AGEP) is a rare, acute neutrophilic dermatosis most commonly triggered by drugs, which typically resolves within 2 weeks following withdrawal of the causative agent. Topical and systemic corticosteroids remain the standard treatment.
Alexandra Junge, Charlotte Vogel, Theresa Hempel, Basil Signer, Nikhil Yawalkar, Kristine Heidemeyer   +5 more
wiley   +1 more source

The Quinazoline Derivative, QNZ, Alleviates Experimental Autoimmune Encephalomyelitis by Suppressing Th1 and Th17 Cells. [PDF]

CNS Neurosci Ther
Yang F, Yang Y, Zhang G, Li J, Chen S, Zhou Y, Kong Y, Luo X, Liu Y, Xu Y, Wang Y.   +10 more
europepmc   +1 more source

New Biologic and Small Molecule Therapies for Hidradenitis Suppurativa

JEADV Clinical Practice, EarlyView.
ABSTRACT Hidradenitis suppurativa (HS) is an inflammatory skin disease that has historically been underdiagnosed and, until recently, under‐researched. Furthermore, the pathophysiology of HS is complex, and not fully understood. Just three biologic medications—adalimumab (anti‐TNF‐α), secukinumab (anti‐IL17A) and bimekizumab (anti‐IL17A/F) are licensed
Emily Pender, Rosalind Hughes, Brian Kirby   +2 more
wiley   +1 more source

A20's linear ubiquitin-binding motif restrains pathogenic activation of Th17 cells and IL-22-driven enteritis. [PDF]

J Clin Invest
Bowman CJ, Stibor DM, Sun X, Lenci N, Shimizu H, Yamashita EF, Advincula R, Kim MC, Turnbaugh JA, Sun Y, Razani B, Turnbaugh PJ, Ye CJ, Malynn BA, Ma A.   +14 more
europepmc   +1 more source

Immunotherapy‐Related Cutaneous Toxicities in Melanoma: A Dermoscopic Perspective

JEADV Clinical Practice, EarlyView.
Dermoscopy serves as a valuable tool in the everyday dermatological and oncological practice for melanoma patients, allowing for the prompt identification of immune‐related cutaneous toxicities and guiding clinicians toward appropriate therapeutic decisions.
Grażyna Kamińska‐Winciorek, Iris Zalaudek, Karolina Zarańska, Bożena Cybulska‐Stopa   +3 more
wiley   +1 more source

Low Th17 cells in patients with cystic fibrosis and allergic broncho-pulmonary aspergillosis. [PDF]

Pediatr Allergy Immunol
Timpano S, Bellicini I, Poli P, Moratto D, Cortesi M, Salvi M, Chiarini M, Padoan R, Pezzotta R, Fiorentini S, Caruso A, Giacomelli M, Badolato R.   +12 more
europepmc   +1 more source

Adoptively transferred Th17 cells cooperate with host B cells to achieve durable tumor immunity. [PDF]

Cancer Cell
Cole AC, Knochelmann HM, Wyatt MM, Wittling MC, Horvat NK, Smith AS, Rangel Rivera GO, Rivera Reyes AM, Pavuluri B, Kumaresan S, Muranski P, Ruffin AT, Boss JM, Lesinski GB, Paulos CM.   +14 more
europepmc   +1 more source

Albumin‐Bilirubin Score as a Novel Prognostic Prediction Tool for Surgically Treated Head and Neck Squamous Cell Carcinoma

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT We investigated the prognostic significance of the preoperative albumin‐bilirubin (ALBI) score in surgically treated head and neck squamous cell carcinoma (HNSCC). This retrospective study included 663 patients who underwent radical surgery between 2007 and 2017.
Ming‐Hsien Tsai, Chao‐Hui Yang, Yu‐Tsai Lin, Hui‐Ching Chuang, Tai‐Lin Huang, Hui Lu, Wen‐Ling Tsai, Chih‐Yen Chien, Fu‐Min Fang   +8 more
wiley   +1 more source

The intrinsic expression of NLRP3 in Th17 cells promotes their protumor activity and conversion into Tregs. [PDF]

Cell Mol Immunol
Accogli T, Hibos C, Milian L, Geindreau M, Richard C, Humblin E, Mary R, Chevrier S, Jacquin E, Bernard A, Chalmin F, Paul C, Ryffel B, Apetoh L, Boidot R, Bruchard M, Ghiringhelli F, Vegran F.   +17 more
europepmc   +1 more source

Natural cutaneous anthrax infection, but not vaccination, induces a CD4(+) T cell response involving diverse cytokines. [PDF]

, 2015
Altmann, DM, Ascough, S, Baillie, L, Boyton, RJ, Doganay, M, Ingram, RJ, Maillere, B, Metan, G, Reynolds, CJ, Robinson, JH, Williamson, DE   +10 more
core   +1 more source