Results 311 to 320 of about 10,836,682 (383)

Mechanical sensing protein PIEZO1 controls osteoarthritis via glycolysis mediated mesenchymal stem cells-Th17 cells crosstalk. [PDF]

Cell Death Dis
Zhou Y, Li M, Lin S, Zhu Z, Zhuang Z, Cui S, Chen L, Zhang R, Wang X, Shen B, Chen C, Yang R.   +11 more
europepmc   +1 more source

Cardiac disease in systemic sclerosis: Integrating pathobiology with clinical management

Rheumatology &Autoimmunity, EarlyView.
Abstract Systemic sclerosis (SSc) is a complex autoimmune disorder in which cardiovascular involvement remains a major determinant of morbidity and mortality. Cardiac injury in SSc results from the interplay of microvascular dysfunction, immune‐mediated inflammation, and progressive interstitial and replacement fibrosis, leading to myocardial disease ...
Henry Sutanto, Betty Rachma, Yuliasih
wiley   +1 more source

Study on serum TL1A levels and their correlation with Th17 cells, IL-17 and IL-21 in children with Graves' disease. [PDF]

Front Immunol
Hao L, Yang J, Lian B, Yin C, Xiao Y, Liu Y.   +5 more
europepmc   +1 more source

Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment

Rare Metals, EarlyView.
ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang, Jiatong Lin, Yi Peng, Zehua Wu, Yingying Liu, Wei Duan, Qiaolin Wei, Jia‐Wei Shen, Jiang‐Xing Chen, Yong Guo   +9 more
wiley   +1 more source

Effect of QingreHuoxue formula on Th17 cells and Tregs in mice with idiopathic membranous nephropathy. [PDF]

Am J Transl Res
Lou C, Zhou Y, Liao J, Xu X, Huang K, Fan X, Hu P, Wang X, Feng B, Zhu F.   +9 more
europepmc   +1 more source

Dendritic Cell–Based Therapeutic Immunization Induces Th1/Th17 Responses and Reduces Fungal Burden in Experimental Sporotrichosis

Juliana Aparecida Jellmayer, Adriana Fernandes de Deus, Matheus Ricardo Curti Gonçalves, Lucas Souza Ferreira, Francine Alessandra Manente, Larissa Silva Pinho Caetano, Fernanda Luiza Piccineli, Thais Zamberço dos Reis Genari, Beatriz da Cunha Saçaki, Tarcísio Passos Ribeiro de Campos, Deivys Leandro Portuondo, Alexander Batista-Duharte, Iracilda Zeppone Carlos   +12 more
openalex   +2 more sources

The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells

, 2015
Bernard Khor, John D Gagnon, Gautam Goel, Marly I. Roche, Kara L. Conway, Khoa Tran, Leslie N. Aldrich, Thomas B. Sundberg, Alison M. Paterson, Scott Mordecai, David Dombkowski, Melanie Schirmer, Pauline H. Tan, Atul K. Bhan, Rahul Roychoudhuri, Nicholas P. Restifo, John J. O’Shea, Benjamin D. Medoff, Alykhan F. Shamji, Stuart L. Schreiber, Arlene H. Sharpe, Stanley Y. Shaw, Ramnik J. Xavier   +22 more
openalex   +2 more sources

Reprogramming Immunogenicity of Iron Oxide Nanoparticles through Sulfated Glycan Presentation

Small, EarlyView.
This study presents a comparative analysis of heparin (HP)‐ and dextran sulfate (DS)‐coated superparamagnetic iron oxide nanoparticles (SPIONs) as a tunable immunomodulatory platform where surface chemistry dictates therapeutic function. DS‐SPIONs are preferentially internalized by myeloid cells, reprogramming them into a pro‐healing M2 phenotype ...
Negin Pournoori, Heela Sarlus, Dick J. Sjöström, Rohith Pavan Parvathaneni, Oommen P. Varghese, Vesa P. Hytönen, Robert A. Harris, Per H. Nilsson, Oommen P. Oommen   +8 more
wiley   +1 more source

Abundance of single filamentous bacteria, and expression of differentiated Th17 cells, their signature cytokine IL-17 A, and retinoic acid receptor are predictive of poor rotavirus vaccine take. [PDF]

Virol J
Bubuluma R, Seheri M, Magwira CA.
europepmc   +1 more source

Phthalate Metabolite, Mono(2‐Ethyl‐5‐Hydroxyhexyl) Phthalate (MEHHP), Promotes Uterine‐Fibroid–Associated Phenotypes in Myometrial Stem Cell‐Derived 3D Organoids

Environmental Toxicology, EarlyView.
ABSTRACT This study investigates how phthalate exposure contributes to uterine fibroid (UF) development by studying the effects of the Mono‐(2‐ethyl‐5‐hydroxyhexyl) phthalate (MEHHP), a metabolite of Di(2‐ethylhexyl) phthalate, on myometrial stem cells (MMSCs).
Somayeh Vafaei, Mervat M. Omran, Qiwei Yang, Sandra Madueke‐Laveaux, Ami R. Zota, Ayman Al‐Hendy, Mohamed Ali   +6 more
wiley   +1 more source