Results 81 to 90 of about 12,148,459 (347)
Th17 cells increase in RRMS as well as in SPMS, whereas various other phenotypes of Th17 increase in RRMS only. [PDF]
, 2020 Background: The nature and extent of inflammation seen in multiple sclerosis (MS) varies throughout the course of the disease. Changes seen in CD4+ T-helper cells in relapsing-remitting (RR) MS and secondary progressive (SP) MS might differ qualitatively
core +1 more source
Journal of Immunology Research, 2021 Several studies showed that IL-17A was significantly increased in nasal polyps (NPs). However, the source and characteristics of IL-17A-producing cells in NPs were not fully understood.
Guangfu Xu +3 more
doaj +1 more source
Th17 Cells in Inflammatory Conditions [PDF]
The Review of Diabetic Studies, 2006 CD4(+) T cells have been subdivided into different subsets, largely on the basis of the cytokines they produce. These subsets include Th1, Th2 and regulatory T cells. Recently, another population of T cells have been described, namely Th17, which are characterized by their production of IL-17.
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Current Opinion in Immunology, 2023 At mucosal barriers, the T helper 17 (TH17) cell population plays a fundamental role in controlling tissue homeostasis. The adaptability of this population to a more pro-inflammatory or anti-inflammatory function - that is, their functional plasticity and consequently heterogeneity - primarily depends on the environment.
Theodora, Agalioti +2 more
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miRNAs Alter T Helper 17 Cell Fate in the Pathogenesis of Autoimmune Diseases
Frontiers in Immunology, 2021 T helper 17 (Th17) cells are characterized by the secretion of the IL-17 cytokine and are essential for the immune response against bacterial and fungal infections.
Junxia Huang, Xinzhi Xu, Ji Yang
doaj +1 more source
Science immunology, 2020 Ongoing classic IL-6 receptor signaling is required to maintain the TH17 program, acting upstream of IL-23 to sustain RORγt expression. TH17 sustenance via IL-6 The pathogenic role of the TH17 subset of CD4+ T cells in multiple immune-mediated diseases ...
Stacey N. Harbour +9 more
semanticscholar +1 more source
The many faces of Th17 cells [PDF]
Current Opinion in Immunology, 2011 Th17 cells have been shown to be strong inducers of tissue inflammation and autoimmune diseases. However, not all Th17 cells are pathogenic and increasing data suggest that Th17 cells may come in different flavors. Thus, Th17 cells cannot be described using a narrow schematic, but instead Th17 cells comprise a wide spectrum with a range of effector ...
Anneli, Peters +2 more
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Trypanosomiasis-induced Th17-like immune responses in carp
, 2010 Background - In mammalian vertebrates, the cytokine interleukin (IL)-12 consists of a heterodimer between p35 and p40 subunits whereas interleukin-23 is formed by a heterodimer between p19 and p40 subunits.
B M Lidy Verburg-van Kemenade +36 more
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Dendritic Cells Regulate Treg-Th17 Axis in Obstructive Phase of Bile Duct Injury in Murine Biliary Atresia. [PDF]
PLoS ONE, 2015 Several cell types are considered to be effector cells in bile duct injury in rhesus rotavirus (RRV)-induced experimental biliary atresia (BA). Here, we identified an increased T helper 17 (Th17) cell population in a BA mode. By depleting the Th17 cells,
Yong-Jun Liu +8 more
doaj +1 more source