Results 91 to 100 of about 79,137 (281)

Porcine kidney xenotransplantation: From primate models to clinical reality

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo   +3 more
wiley   +1 more source

Impact of HIV infection on the frequency and phenotype of Th17 cells in the female genital tract

open access: yes, 2010
Includes bibliographical references (leaves 85-103).T helper (Th) 17 cells have recently been implicated in regulating gut mucosal immunity during HIV infection by sustaining gut mucosal barrier integrity, although they do not respond to HIV directly ...
Salkinder, Amy Leia
core  

Assessment of Th17 lymphocytes and cytokine IL-17A in epithelial ovarian tumors

open access: yesOncology Reports, 2017
The present study was carried out to assess the percentage of T helper 17 (Th17) lymphocytes in blood and tissue and IL-17A serum concentrations in patients with epithelial ovarian tumors. Two isoforms, IL-17A and IL-17F, as well as IL-21 and IL-22, were simultaneously investigated.
Izabela, Winkler   +9 more
openaire   +4 more sources

Recent advances in the construction of humanized animal models and applications in translational medicine

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Substantial advances have been achieved in the development of humanized mouse models, which have proven highly valuable in evaluating cancer immunotherapies and elucidating the mechanisms of infectious diseases. There is now a growing shift in research toward larger animal models—such as pigs—that offer greater physiological similarity to humans ...
Yanan Lyu, Yong‐Guang Yang, Zheng Hu
wiley   +1 more source

Th9 and Th17 Cells in Human Ulcerative Colitis-Associated Dysplastic Lesions

open access: yesClinical Medicine Insights: Oncology
Background: Inflammation is the most important deriving force for the development of colitis-associated colorectal cancer (CAC) through the Inflammation-Pretumor dysplasia-CAC sequence.
Guanglin Cui   +3 more
doaj   +1 more source

Increased NHC Cells in the Peritoneal Cavity of Plasmacytoma Susceptible BALB/c Mouse

open access: yesMediators of Inflammation, 2015
BALB/c strain mice are unique in that they develop murine plasmacytoma (MPC) as a consequence of the inflammation induced by pristane oil injection in the peritoneal cavity.
Berenice Sánchez-González   +3 more
doaj   +1 more source

NEW ASPECTS OF ANTI-INFECTION IMMUNITY

open access: yesИнфекция и иммунитет, 2014
. Four types of adaptive immune response which are regulated by different T-cell populations, namely Th1, Th2, Th17 and T regs have been described.
E. P. Kisseleva
doaj   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

open access: yesAnimal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang   +10 more
wiley   +1 more source

Différenciation des lymphocytes TH17 [PDF]

open access: yesmédecine/sciences, 2008
Vassili Soumelis, Elisabetta Volpe
openaire   +1 more source

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

open access: yesAnimal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang   +6 more
wiley   +1 more source

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