Results 121 to 130 of about 709,386 (365)

Contribution of B-lymphocytes to the production of Interleukin-17 in multiple sclerosis

Неврология, нейропсихиатрия, психосоматика, 2023
The study of pathogenic systems involved in multiple sclerosis (MS) is essential for the development of new therapies.Objective: to determine the contribution of B-lymphocytes to the production of IL-17 in MS with an assessment of the ability of B-cells ...
N. V. Sursyakova, E. M. Kuklina, T. V. Baidina, I. V. Nekrasova, T. N. Trushnikova   +4 more
doaj   +1 more source

Engineering the Immune Response to Biomaterials

Advanced Science, EarlyView.
This paper reviews immune responses to biomaterials, stages of evolution in relation to managing these responses ranging from preventing to modulating them. It also discusses state‐of‐the‐art strategies to modulate these responses and modes of their delivery.
Abolfazl Salehi Moghaddam, Mehran Bahrami, Einollah Sarikhani, Rumeysa Tutar, Yavuz Nuri Ertas, Faleh Tamimi, Ali Hedayatnia, Clotilde Jugie, Houman Savoji, Asma Talib Qureshi, Muhammad Rizwan, Chima V. Maduka, Nureddin Ashammakhi   +12 more
wiley   +1 more source

A review of frequently used Kampo prescriptions part 1. Daikenchuto

Traditional &Kampo Medicine, Volume 9, Issue 3, Page 151-179, December 2022., 2022
Abstract Background The original formula name for daikenchuto (DKT) was written in ‘Jin Gui Yao Lue (Kinkiyōryaku in Japanese)’. DKT as used in Japan consists of four types of crude drug. Key findings Although there are few examples of its use in Chinese classical records, it has begun to be used extensively in modern Japan for intestinal obstruction ...
Takao Namiki, Takayuki Hoshino, Nobuaki Egashira, Toshiaki Kogure, Mari Endo, Masato Homma   +5 more
wiley   +1 more source

Acute Respiratory Distress Syndrome is a TH17-like and Treg immune disease [PDF]

arXiv, 2013
Acute Respiratory Distress Syndrome (ARDS) is a very severe syndrome leading to respiratory failure and subsequent mortality. Sepsis is one of the leading causes of ARDS. Thus, extracellular bacteria play an important role in the pathophysiology of ARDS. Overactivated neutrophils are the major effector cells in ARDS.
arxiv  

An Off‐the‐Shelf Artificial Proregenerative Macrophage for Pressure Ulcer Treatment

Advanced Science, EarlyView.
Artificial macrophages (artM) by encapsulating M2 lysates into biodegradable PLGA microspheres and coated with macrophage membrane, are engineered as new therapeutics against skin pressure ulcer. In mouse models, the artM exhibited robust tissue repair through cell recruitment and microenvironment modulation, showing great therapeutic potential for ...
Qi Su, Jingrong Wang, Yini Huangfu, Rui Gao, Pengxu Kong, Yu Gao, Huijuan Song, Ju Zhang, Pingsheng Huang, Chuangnian Zhang, Zujian Feng, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Unstable Angina is a syndrome correlated to mixed Th17 and Th1 immune disorder [PDF]

arXiv, 2013
Unstable angina is common clinical manifestation of atherosclerosis. However, the detailed pathogenesis of unstable angina is still not known. Here, I propose that unstable angina is a mixed TH17 and TH1 immune disorder. By using microarray analysis, I find out that TH1 and TH17 related cytokine, cytokine receptor, chemokines, complement, immune ...
arxiv  

Mechanisms of Baicalin Alleviates Intestinal Inflammation: Role of M1 Macrophage Polarization and Lactobacillus amylovorus

Advanced Science, EarlyView.
Baicalin alleviates E. coli‐induced intestinal inflammation through dual mechanisms: direct inhibition of the TLR4/IRF/STAT signaling pathway to modulate macrophage polarization and antigen presentation, thereby regulating Th17/Treg cell differentiation; and microbiota‐mediated indirect effects via increasing Lactobacillus amylovorus abundance and ...
Shunfen Zhang, Ruqing Zhong, Miao Zhou, Kai Li, Huiyuan Lv, Huixin Wang, Ye Xu, Dadan Liu, Qiugang Ma, Liang Chen, Hongfu Zhang   +10 more
wiley   +1 more source

Sepsis is a syndrome with hyperactivity of TH17-like innate immunity and hypoactivity of adaptive immunity [PDF]

arXiv, 2013
Currently, there are two major theories for the pathogenesis of sepsis: hyperimmune and hypoimmune. Hyperimmune theory suggests that cytokine storm causes the symptoms of sepsis. On the contrary, hypoimmune theory suggests that immunosuppression causes the manifestations of sepsis.
arxiv  

Colorectal cancer progression is associated with accumulation of Th17 lymphocytes in tumor tissues and increased serum levels of interleukin-6.

Tohoku journal of experimental medicine, 2014
Colorectal cancer is a significant worldwide health problem, and an altered immunoresponse plays an important role in colorectal tumorigenesis and cancer progression.
Xinyi Li, Yanfu Wang, Chao Han, Pai Li, Hua Zhang   +4 more
semanticscholar   +1 more source

Systemic levels of IL-23 are strongly associated with disease activity in rheumatoid arthritis but not spondyloarthritis [PDF]

, 2009
Objectives Th17 cells are an effector T-cell population that plays a role in chronic inflammatory conditions and is dependent on IL-23 for their survival and expansion. More recently, a genetic association was discovered between polymorphisms in the gene
De Keyser, Filip, De Vos, Martine, Elewaut, Dirk, Jacques, Peggy, Kruithof, Elli, Melis, Lode, Mielants, Herman, VANDOOREN, BERNARD, Verbruggen, August   +8 more
core   +1 more source