Results 21 to 30 of about 306,117 (176)
CD4+ cells in autoimmune thyroid disease
Endokrynologia Polska, 2021 The phenomenon of autoimmunity develops as a result of the triggering factor released by damaged cells. This leads to an infiltration of CD4+ cells involved in stimulating the effector cells cytotoxicity and stimulating the humoral response.
Szymon Janyga +5 more
doaj +1 more source
Difference in Th1 and Th17 Lymphocyte Adhesion to Endothelium [PDF]
The Journal of Immunology, 2012 Abstract T cell subset-specific migration to inflammatory sites is tightly regulated and involves interaction of the T cells with the endothelium. Th17 cells often appear at different inflammatory sites than Th1 cells, or both subsets appear at the same sites but at different times.
Pilar, Alcaide +7 more
openaire +2 more sources
Levels of Pathogenic Th17 and Th22 Cells in Patients with Rheumatoid Arthritis
Journal of Immunology Research, 2022 Rheumatoid arthritis (RA) is a chronic autoimmune condition characterized, among others, by tissue damage and activation/differentiation of proinflammatory lymphocytes.
Marlen Vitales-Noyola +7 more
doaj +1 more source
Journal of International Medical Research, 2020 Objective This study investigated the frequency of T-helper (Th)17 lymphocytes and production of cytokine interleukin (IL)-17 in peripheral blood of patients with non-small-cell lung cancer (NSCLC) and their use as a marker of clinical value.
Gang Chen +8 more
doaj +1 more source
Th17 effector cells support B bell responses outside of germinal centres [PDF]
, 2012 Th17 cells are pro-inflammatory CD4+T cells, which are important in immune responses against fungal pathogens and extracellular bacteria and have also been implicated in various autoimmune syndromes.
David R Withers +39 more
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The Role of IL-17 and Th17 Lymphocytes in Autoimmune Diseases [PDF]
Archivum Immunologiae et Therapiae Experimentalis, 2015 The end of twentieth century has introduced some changes into T helper (Th) cells division. The identification of the new subpopulation of T helper cells producing IL-17 modified model of Th1-Th2 paradigm and it was named Th17. High abilities to stimulate acute and chronic inflammation made these cells ideal candidate for crucial player in development ...
Tabarkiewicz, Jacek +4 more
openaire +2 more sources
Differential regulation of interleukin-17 and interferon-y production in inflammatory bowel disease [PDF]
, 2010 PhDBackground and Aims. Interleukin (IL)-17 is now known to be involved in a number of chronic inflammatory disorders. However, the mechanisms regulating its production in inflammatory bowel disease (IBD) are still unclear. Methods.
Rovedatti, Laura
core +4 more sources
The Endogenous Th17 Response in NO
, 2013 Severe, glucocorticoid-resistant asthma comprises 5-7% of patients with asthma. IL-17 is a biomarker of severe asthma, and the adoptive transfer of Th17 cells in mice is sufficient to induce glucocorticoid-resistant allergic airway disease.
Suratt, Benjamin T. +45 more
core +2 more sources
Arterial wall fibrosis in Takayasu arteritis and its potential for therapeutic modulation
Frontiers in Immunology, 2023 Arterial wall damage in Takayasu arteritis (TAK) can progress despite immunosuppressive therapy. Vascular fibrosis is more prominent in TAK than in giant cell arteritis (GCA).
Durga Prasanna Misra +3 more
doaj +1 more source
Immunobiology of IL-17A in human colorectal cancer [PDF]
, 2015 During the last decade tumor infiltration by immune cells has been recognized as a key factor determining clinical outcome. Whereas the presence within tumor tissues of defined lymphocytic populations, including cytotoxic CD8+ T cells and IFN-gamma ...
Amicarella, Francesca
core +1 more source