Results 41 to 50 of about 79,137 (281)
Ultrasound inflammatory parameters and Treg/Th17 cell profiles in established rheumatoid arthritis
Advances in Rheumatology, 2019 Background Imbalance and disfuntion in regulatory T-cells (Tregs) and IL-17 producer lymphocytes (Th17) have been implicated in the pathogenesis of rheumatoid arthritis (RA).
Aline Defaveri do Prado +9 more
doaj +1 more source
Immunomodulation by Bifidobacterium infantis 35624 in the murine lamina propria requires retinoic acid-dependent and independent mechanisms. [PDF]
PLoS ONE, 2013 Appropriate dendritic cell processing of the microbiota promotes intestinal homeostasis and protects against aberrant inflammatory responses. Mucosal CD103(+) dendritic cells are able to produce retinoic acid from retinal, however their role in vivo and ...
Patrycja Konieczna +7 more
doaj +1 more source
Медицинская иммунология, 2018 Diabetes mellitus type 2 is one of the most important non-infectious diseases in the modern world, being an important risk factor of cardiovascular disorders.
I. V. Kologrivova +5 more
doaj +1 more source
The role of Th17 lymphocytes in pathogenesis of autoimmune arthritides [PDF]
Polish Journal of Public Health, 2014 Abstract Th17 cells are newly described population of lymphoctyes, that recruits neutrophils to the site of inflammation and activate inflammatory phenotype of various tissues. They also play a pivotal role in autoimmune diseases and cancers. These cells secrete mainly different isoforms of IL-17, but also IL-21 and IL-22.
Katarzyna Pogoda +4 more
openaire +1 more source
Biochemistry and Biophysics Reports, 2023 Th17 cells triggered inflammation is a critical element in cerebral ischemic injury, and the gut microbiota intricately impacts T lymphocytes. Nevertheless, it remains unclear whether the gut microbiota involves in cardiac arrest/cardiopulmonary ...
Qin Yuan +7 more
doaj +1 more source
Autoreactive lymphocytes in multiple sclerosis: Pathogenesis and treatment target
Frontiers in Immunology, 2022 Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) characterized by destruction of the myelin sheath structure.
Rongzeng Liu +10 more
doaj +1 more source
Trypanosomiasis-induced Th17-like immune responses in carp
, 2010 Background - In mammalian vertebrates, the cytokine interleukin (IL)-12 consists of a heterodimer between p35 and p40 subunits whereas interleukin-23 is formed by a heterodimer between p19 and p40 subunits.
B M Lidy Verburg-van Kemenade +36 more
core +1 more source
Balance between Regulatory T and Th17 Cells in Systemic Lupus Erythematosus: The Old and the New
Clinical and Developmental Immunology, 2012 Pathogenic mechanisms underlying the development of systemic lupus erythematosus (SLE) are very complex and not yet entirely clarified. However, the pivotal role of T lymphocytes in the induction and perpetuation of aberrant immune response is well ...
Alessia Alunno +8 more
doaj +1 more source
T-bet Regulates the Fate of Th1 and Th17 Lymphocytes in Autoimmunity [PDF]
The Journal of Immunology, 2007 Abstract IL-17-producing T cells (Th17) have recently been implicated in the pathogenesis of experimental autoimmune encephalomyelitis (EAE), an animal model for the human disease multiple sclerosis. However, little is known about the transcription factors that regulate these cells. Although it is clear that the transcription factor T-
Anne R, Gocke +6 more
openaire +2 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source