Results 11 to 20 of about 306,117 (176)

The Multifaceted Role of Th17 Lymphocytes and Their Associated Cytokines in Cancer [PDF]

Clinical and Developmental Immunology, 2013
While the role of T helper 17 lymphocytes (Th17) in the pathogenesis of autoimmune diseases and in infectious immunity has been relatively well defined, the impact of these cells and their associated cytokines on cancer development is still under debate.
Darya Alizadeh, Emmanuel Katsanis, Nicolas Larmonier   +2 more
doaj   +6 more sources

Involvement of CD26 in Differentiation and Functions of Th1 and Th17 Subpopulations of T Lymphocytes [PDF]

Journal of Immunology Research, 2021
CD26, acting as a costimulator of T cell activation, plays an important role in the immune system. However, the role of CD26 in the differentiation of T cell subsets, especially of new paradigms of T cells, such as Th17 and Tregs, is not fully clarified.
Xiangli Zhao, Wenhan Wang, Kai Zhang, Jingya Yang, Hendrik Fuchs, Hua Fan   +5 more
doaj   +5 more sources

Novel Th17 Lymphocyte Populations, Th17.1 and PD1+Th17, are Increased in Takayasu Arteritis, and Both Th17 and Th17.1 Sub-Populations Associate with Active Disease

Journal of Inflammation Research, 2022
Kritika Singh,1,* Upendra Rathore,1,* Mohit Kumar Rai,1 Manas R Behera,2 Neeraj Jain,3 Manish Ora,4 Dharmendra Bhadauria,2 Supriya Sharma,5 Gaurav Pande,6 Sanjay Gambhir,4 Alok Nath,7 Sudeep Kumar,8 Aman Sharma,9 Vikas Agarwal,1 Durga Prasanna Misra1 ...
Singh K, Rathore U, Rai MK, Behera MR, Jain N, Ora M, Bhadauria D, Sharma S, Pande G, Gambhir S, Nath A, Kumar S, Sharma A, Agarwal V, Misra DP   +14 more
doaj   +4 more sources

The potential role of Th17 lymphocytes in patients with psoriasis. [PDF]

An Bras Dermatol, 2018
Psoriasis is a chronic inflammatory disorder, characterized by increased keratinocyte proliferation due to abnormal differentiation of basal keratinocytes. The etiology of the disease is unclear, and according to the survey results, it is hypothesized that a combination of genetic and environmental factors prompts an abnormal immune response in ...
Mansouri M, Mansouri P, Raze AA, Jadali Z.   +3 more
europepmc   +7 more sources

Cigarette smoking induces human CCR6⁺Th17 lymphocytes senescence and VEGF-A secretion. [PDF]

Sci Rep, 2020
International audienceChronic exposure to environmental pollutants is often associated with systemic inflammation. As such, cigarette smoking contributes to inflammation and lung diseases by inducing senescence of pulmonary cells such as pneumocytes ...
Baskara I, Kerbrat S, Dagouassat M, Nguyen HQ, Guillot-Delost M, Surenaud M, Baillou C, Lemoine FM, Morin D, Boczkowski J, Le Gouvello S.   +10 more
europepmc   +2 more sources

Regulatory T lymphocytes/Th17 lymphocytes imbalance in autism spectrum disorders: evidence from a meta-analysis. [PDF]

Mol Autism, 2021
International audienceBackground: Immune system dysfunction has been proposed to play a critical role in the pathophysiology of autism spectrum disorders (ASD). Conflicting reports of lymphocyte subpopulation abnormalities have been described in numerous
Ellul P, Ellul P, Rosenzwajg M, Peyre H, Fourcade G, Mariotti-Ferrandiz E, Trebossen V, Klatzmann D, Delorme R.   +8 more
europepmc   +2 more sources

Expansion, isolation and first characterization of bovine Th17 lymphocytes. [PDF]

Sci Rep, 2019
AbstractInterleukin 17A-producing T helper cells (Th17) are CD4+ T cells that are crucial to immunity to extracellular bacteria. The roles of these cells in the bovine species are poorly defined, because the characterization of bovine Th17 cells lags behind for want of straightforward cultivation and isolation procedures.
Cunha P, Vern YL, Gitton C, Germon P, Foucras G, Rainard P.   +5 more
europepmc   +7 more sources

Th1, Th2 and Th17 lymphocytes in autoimmune thyreopathies [PDF]

Vnitřní lékařství, 2021
Among the most common organ-specific autoimmune diseases are autoimmune thyreopathies. We have focused on the importance of Th1, Th2 and Th17 lymphocytes in autoimmune thyroiditis (AT). The cohort consisted of 136 treated patients in the full clinical course of AT (24 men, mean age 41.0±16.8 years and 112 women, mean age 44.6±17.6 years).
Karolína, Absolonová, Petr, Matucha, Ivan, Šterzl   +2 more
openaire   +2 more sources

The parasitic helminth product ES-62 suppresses pathogenesis in collagen-induced arthritis by targeting the interleukin-17–producing cellular network at multiple sites [PDF]

, 2012
Among many survival strategies, parasitic worms secrete molecules to modulate host immune responses. One such product, ES-62, is protective in the collagen-induced arthritis (CIA) model of rheumatoid arthritis.
Harnett, M.M., Pineda, Miguel, McGrath, Mairi, Al-Riyami, Lamyaa, Pineda, M.A., Harnett, W., Pauline C. Smith, Lamyaa Al-Riyami, Harnett, Margaret, Miguel A. Pineda, Smith, P.C., Smith, Pauline, J. Alastair Gracie, Harnett, William, McGrath, M.A., Rzepecka, J., Gracie, Alastair, Rzepecka, Justyna, Margaret M. Harnett, Al-Riyami, L., Gracie, J.A., Justyna Rzepecka, Mairi A. McGrath, William Harnett   +23 more
core   +4 more sources

Microenvironmental Th9 and Th17 lymphocytes induce metastatic spreading in lung cancer. [PDF]

J Clin Invest, 2020
Immune microenvironment plays a critical role in lung cancer control versus progression and metastasis. In this investigation, we explored the effect of tumor-infiltrating lymphocyte subpopulations on lung cancer biology by studying in vitro cocultures, in vivo mouse models, and human lung cancer tissue.
Salazar Y, Zheng X, Brunn D, Raifer H, Picard F, Zhang Y, Winter H, Guenther S, Weigert A, Weigmann B, Dumoutier L, Renauld JC, Waisman A, Schmall A, Tufman A, Fink L, Brüne B, Bopp T, Grimminger F, Seeger W, Pullamsetti SS, Huber M, Savai R.   +22 more
europepmc   +5 more sources