Results 161 to 170 of about 10,689,174 (395)

CD28-Dependent CTLA-4 Expression Fine-Tunes the Activation of Human Th17 Cells

iScience, 2020
Summary: Previous work has demonstrated that Th17 memory cells but not Th1 cells are resistant to CD28/CTLA-4 blockade with CTLA-4 Ig, leading us to investigate the individual roles of the CD28 and CTLA-4 cosignaling pathways on Th1 versus Th17 cells. We
Scott M. Krummey, Christina R. Hartigan, Danya Liu, Mandy L. Ford   +3 more
doaj  

The Imbalance between Foxp3+Tregs and Th1/Th17/Th22 Cells in Patients with Newly Diagnosed Autoimmune Hepatitis

Journal of Immunology Research, 2018
This study is aimed at examining the potential role of regulatory T- (Treg-) Th1-Th17-Th22 cells in the pathogenic process of autoimmune hepatitis (AIH). The numbers of Foxp3+Tregs and Th1, Th17, and Th22 cells were measured in 32 AIH patients using flow
Ma Liang, Zhang Liwen, Zhuang Yun, Ding Yanbo, Chen Jianping   +4 more
doaj   +1 more source

Th1 cell anergy and blockade in G1a phase of the cell cycle. [PDF]

, 1993
Katabarwa Murenzi Gilbert, William O. Weigle   +1 more
openalex   +1 more source

Novel Less Toxic, Lymphoid Tissue‐Targeted Lipid Nanoparticles Containing a Vitamin B5‐Derived Ionizable Lipid for mRNA Vaccine Delivery

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo, Muhammad Faisal, Seo‐Hyeon Bae, Kounghwa Youn, Hyo‐Jung Park, Sung Pil Kwon, Il Kwon Hwang, Jisun Lee, Hyeong Jun Kim, Jae‐Hwan Nam, Gyochang Keum, Eun‐Kyoung Bang   +11 more
wiley   +1 more source

A molecular signature for IL-10-producing Th1 cells in protozoan parasitic diseases. [PDF]

JCI Insight, 2023
Edwards CL, Engel JA, de Labastida Rivera F, Ng SS, Corvino D, Montes de Oca M, Frame TC, Chauhan SB, Singh SS, Kumar A, Wang Y, Na J, Mukhopadhyay P, Lee JS, Nylen S, Sundar S, Kumar R, Engwerda CR.   +17 more
europepmc   +1 more source

Heterogeneity of helper/inducer T lymphocytes. IV. Stimulation of resting and activated B cells by Th1 and Th2 clones. [PDF]

, 1990
Abul K. Abbas, Sandy S. Urioste, Tucker Collins, W H Boom   +3 more
openalex   +1 more source

Co‐Delivery of Multiple Toll‐Like Receptor Agonists and Avian Influenza Hemagglutinin on Protein Nanoparticles Enhances Vaccine Immunogenicity and Efficacy

Advanced Healthcare Materials, Volume 14, Issue 10, April 15, 2025.
This research highlights a novel application of protein nanoparticles to effectively modulate the strength, breadth, and bias of an immune response against influenza virus. Nanoparticles precisely co‐delivering antigen (H5) and multiple adjuvants (CpG and FliCc) present a way to improve and direct prophylactic immune responses which can be applicable ...
Aaron Ramirez, Jenny E. Hernandez‐Davies, Aarti Jain, Lu Wang, Erwin Strahsburger, D. Huw Davies, Szu‐Wen Wang   +6 more
wiley   +1 more source

The relevance of TH1 and TH2 cells in immediate and nonimmediate reactions to gelatin-containing vaccine [PDF]

, 1999
Masaya Ohsaki, Hiroyuki Tsutsumi, Takuji Kumagai, Tatsuru Yamanaka, Yasuhiko Wataya, Hidetsugu Furukawa, Hiroyuki Kojima, Akiko Saito, Shoki Yano, Shunzo Chiba   +9 more
openalex   +1 more source

Motor‐Free Soft Robots for Cancer Detection, Surgery, and In Situ Bioprinting

Advanced Healthcare Materials, EarlyView.
Novel motor‐free soft robots for cancer detection, surgery, and in situ bioprinting–are presented. This master‐slave system is constructed from soft fibrous syringe architectures, removing the need for electrical motors and complex control mechanisms, while reducing the physical tremors.
Chi Cong Nguyen, James Davies, Aditya Ashok, Trung Thien Hoang, Anahid Ehteda, Tran Bach Dang, Emanuele Nicotra, Hien A. Tran, Bibhu Sharma, Kefan Zhu, Phuoc Thien Phan, Adrienne Ji, Jingjing Wan, Jelena Rnjak‐Kovacina, Orazio Vittorio, Hoang‐Phuong Phan, Nigel Hamilton Lovell, Thanh Nho Do   +17 more
wiley   +1 more source

Replicator Dynamics of of Cancer Stem Cell; Selection in the Presence of Differentiation and Plasticity [PDF]

arXiv, 2014
Stem cells have the potential to produce lineages of non-stem cell populations (differentiated cells) via a ubiquitous hierarchal division scheme. Differentiation of a stem cell into (partially) differentiated cells can happen either symmetrically or asymmetrically. The selection dynamics of a mutant cancer stem cell should be investigated in the light
arxiv