Results 181 to 190 of about 10,689,174 (395)

Th1 cells inducing IFNγ response improves immunotherapy efficacy in gastric cancer. [PDF]

Chin J Cancer Res, 2023
Cao Q, Xue R, Zhang N.
europepmc   +1 more source

Peroxisome proliferator-activated receptor (PPAR)alpha expression in T cells mediates gender differences in development of T cell-mediated autoimmunity. [PDF]

, 2007
Peroxisome proliferator-activated receptor (PPAR)alpha is a nuclear receptor that mediates gender differences in lipid metabolism. PPARalpha also functions to control inflammatory responses by repressing the activity of nuclear factor kappaB (NF-kappaB ...
Baranzini, Sergio E, Crowell, Andrea, Dunn, Shannon E, Loh, John, Oksenberg, Jorge, Ousman, Shalina S, Sobel, Raymond A, Steinman, Lawrence, Youssef, Sawsan, Zuniga, Luis   +9 more
core  

Orally Induced Peripheral Nonresponsiveness Is Maintained in the Absence of Functional Th1 or Th2 Cells [PDF]

, 1999
Hai Ning Shi, Michael J. Grusby, Cathryn Nagler‐Anderson   +2 more
openalex   +1 more source

Off‐The‐Shelf Multivalent Nanoconjugate Cancer Vaccine Rescues Host Immune Response against Melanoma

Advanced Materials, Volume 37, Issue 16, April 23, 2025.
A star‐shaped cross‐linked polyglutamate (StCl) nanocarrier delivers melanoma‐associated peptide antigens via redox‐responsive linkers, inducing lymph node‐targeted antigen presentation. The nanoconjugate activates dendritic cells, promotes effector T‐cell responses, and enables tumor regression even in humanized patient‐derived preclinical models ...
Liane IF Moura, Alessio Malfanti, Ana I Matos, Carina Peres, Ana Armiñán, Aroa Duro‐Castaño, Inmaculada Conejos‐Sánchez, María Medel, Snežana Đorđević, Paula Carrascosa, Bárbara Carreira, Rita C Acúrcio, Helena Xavier‐Ferreira, Alberto Hernández‐Barranco, Elena Castellano, Esther Roselló, José C. Machado, Héctor Peinado, María J. Vicent, Helena F. Florindo   +19 more
wiley   +1 more source

NFIL3/Tim3 axis regulates effector Th1 inflammation in COPD mice

Frontiers in Immunology
BackgroundIFN-γ+CD4+ cells (type 1 helper T cells, Th1) represent a critical component of the inflammatory environment in the lungs of chronic obstructive pulmonary disease (COPD). Identifying influencing factors related to COPD-associated Th1 cells will
Junyi Ke, Junyi Ke, Shu Huang, Shu Huang, Zhixiong He, Siyu Lei, Siyu Lei, Shiya Lin, Yinying Li, Qiuming Li, Hui Huang, Hongchun Huang, Huajiao Qin, Minchao Duan   +13 more
doaj   +1 more source

Cell mechanics, environmental geometry, and cell polarity control cell-cell collision outcomes [PDF]

arXiv
Interactions between crawling cells, which are essential for many biological processes, can be quantified by measuring cell-cell collisions. Conventionally, experiments of cell-cell collisions are conducted on two-dimensional flat substrates, where colliding cells repolarize and move away upon contact with one another in "contact inhibition of ...
arxiv  

A multidrug-resistance protein (MRP)-like transmembrane pump is highly expressed by resting murine T helper (Th) 2, but not Th1 cells, and is induced to equal expression levels in Th1 and Th2 cells after antigenic stimulation in vivo. [PDF]

, 1998
Michael Lohoff, Stefan Prechtl, Frank Sommer, M Roellinghoff, Earlene M. Schmitt, Gernot Gradehandt, Peter Rohwer, Brenda D. Stride, Susan P.C. Cole, R G Deeley   +9 more
openalex   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Elevated profiles of peripheral Th22, Th17, Th2 cells, and decreased percentage of Th1 cells in breast cancer patients. [PDF]

Thorac Cancer, 2023
Peng Z, Dong X, He M, Zhao Y, Liu Y, Li M, Li G, Wang X, Li L, Hu Y.   +9 more
europepmc   +1 more source

Activation of STAT Proteins and Cytokine Genes in Human Th1 and Th2 Cells Generated in the Absence of IL-12 and IL-4 [PDF]

, 1998
Richard Moriggl, Colette Kristofic, B Kinzel, Siniša Volarević, Bernd Groner, Volker Brinkmann   +5 more
openalex   +1 more source