Results 221 to 230 of about 10,689,174 (395)

ROS‐Responsive Microneedle Patches Enable Peri‐Lacrimal Gland Therapeutic Administration for Long‐Acting Therapy of Sjögren's Syndrome‐Related Dry Eye

Advanced Science, Volume 12, Issue 16, April 24, 2025.
A new strategy for constructing smart gel‐based MN patches is developed to overcome the insufficient drug delivery of eye drops to the lacrimal gland. The gel‐based MN patches achieved long‐acting drug release in a ROS‐responsive manner, and separable base in a temperature‐responsive manner.
Jingqing Mu, Xiangyu Ding, Yapeng Song, Baoyue Mi, Xiaolong Fang, Baihua Chen, Bin Yao, Xuguang Sun, Xiaoyong Yuan, Shutao Guo, Xia Hua   +10 more
wiley   +1 more source

Comparative Analysis of Apigenin-3 Acetate versus Apigenin and Methyl-Prednisolone in Inhibiting Proliferation and Gene Expression of Th1 Cells in Multiple Sclerosis. [PDF]

Cell J, 2023
Kasiri N, Ghannadian SM, Hosseini R, Ahmadi L, Rahmati M, Ashtari F, Pourazar A, Eskandari N.   +7 more
europepmc   +1 more source

Kinetics of Th1 and Th2 cytokine production during the early course of acute and chronic murine graft-versus-host disease. Regulatory role of donor CD8+ T cells. [PDF]

, 1995
Violeta Rus, A Svetić, Phan Nguyen, William C. Gause, Charles S. Via   +4 more
openalex   +1 more source

Microbiota‐Derived Inosine Suppresses Systemic Autoimmunity via Restriction of B Cell Differentiation and Migration

Advanced Science, EarlyView.
Lactobacillus johnsonii and its associated purine metabolite inosine not only restrict systemic B cell differentiation, but also contribute to immune cell infiltration in the kidneys, thereby serving dual functions in mitigating the progression of systemic lupus erythematosus (SLE).
Lingyu Gao, Yuhan Zhang, Zhi Hu, Shengwen Chen, Qiaolin Wang, Yong Zeng, Huiqi Yin, Junpeng Zhao, Yijing Zhan, Changxing Gao, Yue Xin, Bing Chen, Stijn van der Veen, Ming Zhao, Deyu Fang, Qianjin Lu   +15 more
wiley   +1 more source

The FoxO4/DKK3 axis represses IFN-γ expression by Th1 cells and limits antimicrobial immunity. [PDF]

J Clin Invest, 2022
Chen X, Hu J, Wang Y, Lee Y, Zhao X, Lu H, Zhu G, Wang H, Jiang Y, Liu F, Chen Y, Kim BS, Zhou Q, Liu X, Wang X, Chang SH, Dong C.   +16 more
europepmc   +1 more source

Effects of TH1 and TH2 cytokines on CD8+ cell response against human immunodeficiency virus: implications for long-term survival.

, 1995
Edward Barker, Carl E. Mackewicz, Jay A. Levy   +2 more
openalex   +1 more source

Expression and Function of CTLA-4 in Th1 and Th2 Cells [PDF]

, 1998
Maria‐Luisa Alegre, Helena Shiels, Craig B. Thompson, Thomas F. Gajewski   +3 more
openalex   +1 more source

Bone Marrow‐Derived Mesenchymal Stromal Cells Harness Purinergenic Signaling to Tolerize Human Th1 Cells In Vivo

Stem Cells, 2015
Shoba Amarnath, J. Foley, D. Farthing, R. Gress, A. Laurence, M. Eckhaus, J. Métais, J. Rose, F. Hakim, T. Felizardo, Austin V. Cheng, P. Robey, D. Stroncek, M. Sabatino, M. Battiwalla, S. Ito, D. Fowler, A. Barrett   +17 more
semanticscholar   +1 more source

Nanotherapy for Neural Retinal Regeneration

Advanced Science, EarlyView.
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu, Li Dong, Yujia Lv, Xuhan Shi, Ruiheng Zhang, Wenda Zhou, Haotian Wu, Heyan Li, Yitong Li, Zhou Li, Dan Luo, Wen‐Bin Wei   +11 more
wiley   +1 more source

Evolutionarily conserved IL-27β enhances Th1 cells potential by triggering the JAK1/STAT1/T-bet axis in Nile tilapia. [PDF]

Fish Shellfish Immunol Rep, 2023
Geng M, Li K, Ai K, Liang W, Yang J, Wei X.   +5 more
europepmc   +1 more source