Results 241 to 250 of about 198,196 (300)
Successful treatment of eosinophilic esophagitis with upadacitinib prescribed for atopic dermatitis
Abstract We describe a pediatric patient treated with upadacitinib for atopic dermatitis (AD) who subsequently achieved sustained clinical and histologic remission of eosinophilic esophagitis (EoE). Upadacitinib is an oral small molecule selective Janus kinase 1 inhibitor that inhibits janus kinase‐signal transduction and activation of transcription ...
Nathalie Nguyen, Maureen Bauer
wiley +1 more source
Gut function among children treated for severe acute malnutrition: A cohort study in Uganda
Abstract Objectives Impaired gut function in children with severe acute malnutrition (SAM) is associated with morbidity. We aimed to assess changes in six biomarkers representing different domains of gut function among children with complicated SAM during nutritional rehabilitation, and to identify predictors of these changes.
Betty Lanyero +12 more
wiley +1 more source
JAK Inhibitors in Psoriatic–Atopic Dermatitis Overlap: A Four‑Case Series
ABSTRACT Overlap between psoriasis and atopic dermatitis (AD) poses diagnostic and therapeutic challenges; monoclonal antibodies targeting a single axis may improve one component while worsening the other [1]. Janus kinase (JAK) inhibitors act pleiotropically and may provide simultaneous control of psoriatic and eczematous inflammation [2].
Eleonora Bongiovanni +6 more
wiley +1 more source
IFN-γ-producing T<sub>H</sub>1 cells and dysfunctional regulatory T cells contribute to the pathogenesis of Sjögren's disease. [PDF]
Wang YH +14 more
europepmc +1 more source
Painful Bilateral Necrosis of the Scalp
JEADV Clinical Practice, EarlyView.
Zoé Dumesnil +6 more
wiley +1 more source
Effects of nitric oxide on the induction and differentiation of Th1 cells
We have previously shown that mice lacking inducible NO synthase are markedly more susceptible to Leishmania major infection but developed a significantly enhanced Th1 cell response compared with wild-type mice.
Wanda Niedbala +2 more
exaly +2 more sources
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Current Opinion in Hematology, 2001
After activation, CD4 helper T (Th) cells differentiate into Th1or Th2 effector subsets. These two types of cells produce distinct profiles of cytokines and regulate different immune responses. This review summarizes recent progress on different features of co-stimulatory regulation and chemokine-mediated homing of Th1 and Th2 cells.
C, Dong, R A, Flavell
openaire +2 more sources
After activation, CD4 helper T (Th) cells differentiate into Th1or Th2 effector subsets. These two types of cells produce distinct profiles of cytokines and regulate different immune responses. This review summarizes recent progress on different features of co-stimulatory regulation and chemokine-mediated homing of Th1 and Th2 cells.
C, Dong, R A, Flavell
openaire +2 more sources
Dysregulated Th1 cells in lung squamous cell carcinoma
Journal of Leukocyte Biology, 2022AbstractLung squamous cell carcinoma (LUSC) is a common subtype of lung cancer. Th1 cells contribute to antitumor immune responses. However, there are few studies on Th1 cells in LUSC. CD8+ T cells are the main driver of the antitumor immunity, targeting tumor cells killing. Th1 cells play an important auxiliary role in this process.
Jiahui, Wang +6 more
openaire +2 more sources
An Update on Human Th1 and Th2 Cells
International Archives of Allergy and Immunology, 2009The existence of functionally polarized human T cell responses based on their profile of cytokine secretion in both the CD4+ T helper (Th) and the CD8+ T cytotoxic cell subset has been established. Human Th1 and Th2 cells not only produce a different set of cytokines but also exhibit distinct functional properties and preferential expression of some ...
ROMAGNANI, SERGIO +11 more
openaire +6 more sources

