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Biology of human TH1 and TH2 cells
Journal of Clinical Immunology, 1995Evidence is accumulating to suggest the existence of polarized human T-cell responses, reminiscent of TH1 and TH2 subsets described for mouse T cells. Human TH1 cells preferentially develop during infections by intracellular bacteria and trigger phagocyte-mediated host defense, whereas TH2 cells, which predominate during helminthic infestations and in ...
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Analysis of Th1/Th2 T-Cell Subsets
2007Specific immune responses are mediated by activated CD4+ T-helper (Th) cells. Two major subsets, denoted Th1 and Th2, have been identified that are characterized by their distinctive cytokine secretion pattern and associated effector functions. The signature cytokines of Th1 and Th2 cells are interferon-gamma and interleukin-4, respectively. Because of
Alla, Skapenko, Hendrik, Schulze-Koops
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Two sequential activation modules control the differentiation of protective T helper-1 (Th1) cells
Immunity, 2021Sung-Wook Hong +2 more
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Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells
Nature Immunology, 2021Daniel Chauss +2 more
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TH1 cells control themselves by producing interleukin-10
Nature Reviews Immunology, 2007Anne O'Garra, Paulo Vieira
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Molecular Mechanisms RegulatinG Th1 Immune Responses
Annual Review of Immunology, 2003Stanford L Peng, Laurie H Glimcher
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