Results 301 to 310 of about 10,822,632 (330)

[Th1 cells, Th2 cells and atopic dermatitis].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1997
The immunological hallmark of atopic dermatitis (AD) is a Th1/Th2 dysbalance. The reaction to high molecular weight environmental allergens (e.g. pollen, house dust mites), production of IgE and activation of eosinophil granulocytes result from Th2 dominance. The Th2-cytokine interleukin-4 (IL-4) is necessary for IgE synthesis.
I, Böhm, R, Bauer
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Dendritic cell regulation of TH1-TH2 development

Nature Immunology, 2000
Understanding the control exerted by cytokines on T helper cell subsets 1 and 2 (TH1-TH2) development has progressed to a fairly satisfying knowledge of intracellular signals and transcription factors. Less is understood about the molecular basis of TH1-TH2 development exerted by other parameters, such as how the antigen presenting cell can influence ...
Moser, Muriel, Murphy, Kevin
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CD4+ cell memory: the enigma of Th1 cells

Trends in Molecular Medicine, 2003
Despite a wealth of information pertaining to functional and phenotypic attributes of memory CD4(+) cells, the mechanisms that underlie the generation and persistence of memory in this subset are largely unknown. Recent work suggests that the development of memory might be differently regulated in T-helper-1 and T-helper-2 cells, owing to differences ...
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Th1/Th2 Cell Differentiation and Molecular Signals

2014
The distinctive differentiated states of the CD4+ T helper cells are determined by the set of transcription factors and the genes transcribed by the transcription factors. In vitro induction models, the major determinants of the cytokines present during the T-cell receptor (TCR)-mediated activation process.
Yuan, Zhang, Yaguang, Zhang, Wangpeng, Gu, Bing, Sun   +3 more
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Th1/Th2 Cell’s Function in Immune System

2014
CD4+ T helper cells regulate appropriate cellular and humoral immune responses to a wide range of pathogens and get involved in many diseases progress. The balance of the earliest determined CD4+ T helper cell subsets, Th1 and Th2, play an important role in allergy and autoimmune diseases.
Yuan, Zhang, Yaguang, Zhang, Wangpeng, Gu, Lan, He, Bing, Sun   +4 more
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Biology of human TH1 and TH2 cells

Journal of Clinical Immunology, 1995
Evidence is accumulating to suggest the existence of polarized human T-cell responses, reminiscent of TH1 and TH2 subsets described for mouse T cells. Human TH1 cells preferentially develop during infections by intracellular bacteria and trigger phagocyte-mediated host defense, whereas TH2 cells, which predominate during helminthic infestations and in ...
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Analysis of Th1/Th2 T-Cell Subsets

2007
Specific immune responses are mediated by activated CD4+ T-helper (Th) cells. Two major subsets, denoted Th1 and Th2, have been identified that are characterized by their distinctive cytokine secretion pattern and associated effector functions. The signature cytokines of Th1 and Th2 cells are interferon-gamma and interleukin-4, respectively. Because of
Alla, Skapenko, Hendrik, Schulze-Koops
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Lnc‐DC mediates the over‐maturation of decidual dendritic cells and induces the increase in Th1 cells in preeclampsia

American Journal of Reproductive Immunology, 2017
Wen Zhang, Yang Zhou, Yiling Ding
semanticscholar   +1 more source

Role of T-bet in Commitment of TH1 Cells Before IL-12-Dependent Selection

Science, 2001
Alan C. Mullen, F. High, Anne S. Hutchins, Hubert W. Lee, A. Villarino, D. Livingston, A. Kung, N. Cereb, T. Yao, S. Yang, S. Reiner   +10 more
semanticscholar   +1 more source

Th1 and Th2 cells

Research in Immunology, 1998
Romagnani, S., Kapsenberg, M., Radbruch, A., Adorini, L.   +3 more
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