Results 301 to 310 of about 10,689,174 (395)

Extending the CD4⁺T-Cell Epitope Specificity of the Th1 Immune Response to an Antigen Using aSalmonella entericaSerovar Typhimurium Delivery Vehicle [PDF]

, 2000
Richard Lo‐Man, Jan Langeveld, Edith Dériaud, Muguette Jéhanno, Marie Rojas, Jean-Marie Clément, R. H. Meloen, Maurice Hofnung, Claude Leclerc   +8 more
openalex   +1 more source

Regulation of Th1 Cells and Experimental Autoimmune Encephalomyelitis by Glycogen Synthase Kinase-3

Journal of Immunology, 2013
E. Beurel, O. Kaidanovich‐Beilin, Wen-I Yeh, Ling Song, V. Palomo, S. Michalek, J. Woodgett, L. Harrington, H. Eldar-Finkelman, Ana Martínez, R. Jope   +10 more
semanticscholar   +1 more source

Targeting Antigen‐Presenting Cells to Enhance the Tumor‐Spleen Immunity Cycle through Liposome‐Neoantigen Vaccine

Advanced Science, EarlyView.
LNPsD18, a cationic liposome that enhances antigen‐presenting cell uptake in the spleen and tumor without targeting ligands is developed. Co‐delivering neoantigens and a TLR9 agonist significantly improve DC activation, tumor immunity, and survival in liver and colorectal cancer models, demonstrating the importance of dual‐site APC targeting for cancer
Yu Xu, Bing Wang, Yue Huang, JianPing Liao, Chenyi Wu, Chenxi Zhou, Zishi Kang, Shiyang Jiang, Bing‐Chen Wu, Da Zhang, Ruihua Xu, Xiaolong Liu, Feng Wang   +12 more
wiley   +1 more source

TH1 but not TH0 cell help is efficient to induce cytotoxic T lymphocytes by immunization with short synthetic peptides [PDF]

, 2000
Ascensión López-Dı́az de Cerio, Noëlia Casares, J.J. Lasarte, Pablo Sarobe, Alberto Pérez‐Mediavilla, M. Ruiz, Jorge A. Prieto, Francisco Borrás‐Cuesta   +7 more
openalex   +1 more source

Genetically Engineered IL12/CSF1R‐Macrophage Membrane‐Liposome Hybrid Nanovesicles for NIR‐II Fluorescence Imaging‐Guided and Membrane‐Targeted Mild Photothermal‐Immunotherapy of Glioblastoma

Advanced Science, EarlyView.
A theranostic nanoplatform is formulated with NIR‐II emissive lipophilic cyanine dye IRC18 to intercalate into genetically engineered IL12/CSF1R‐macrophage membrane‐liposome hybrid nanovesicles, which assists to achieve blood–brain barrier crossing, glioblastoma targeting, NIR‐II fluorescence imaging, image‐guided membrane‐targeted mild photothermal ...
Pengfei Chen, Yue Liu, Haiyan Huang, Menglong Li, Hui Xie, Shubham Roy, Jingsi Gu, Jian Jin, Kai Deng, Lixin Du, Bing Guo   +10 more
wiley   +1 more source

MALT1 positively correlates with Th1 cells, Th17 cells, and their secreted cytokines and also relates to disease risk, severity, and prognosis of acute ischemic stroke. [PDF]

J Clin Lab Anal, 2021
Chen X, Zhang X, Lan L, Xu G, Li Y, Huang S.   +5 more
europepmc   +1 more source

IFN-γ Production by Amyloid β–Specific Th1 Cells Promotes Microglial Activation and Increases Plaque Burden in a Mouse Model of Alzheimer’s Disease

Journal of Immunology, 2013
T. Browne, Keith McQuillan, R. McManus, Julie‐Ann O'Reilly, K. Mills, M. Lynch   +5 more
semanticscholar   +1 more source

Dopant‐Regulated Piezocatalysts Evoke Sonopiezoelectric and Enzymatic PANoptosis for Synergistic Cancer Therapy

Advanced Science, Volume 12, Issue 17, May 8, 2025.
Engineered Mn‐substituted HfO2 (HMO) is identified with enhanced sonopiezoelectric effects and multienzymatic activities, promoting reactive oxygen species generation and amplifying oxidative stress in cancer cells. Upon ultrasound irradiation, HMO evokes cancer cell PANoptosis, thereby triggering robust antitumor immunity.
Linhong Zhong, Xun Guo, Liming Deng, Xiaoting Wang, Hongye He, Nianhong Wu, Rui Tang, Liang Chen, Yu Chen, Pan Li   +9 more
wiley   +1 more source

C8/119S Mutation of Major Mite Allergen Derf-2 Leads to Degenerate Secondary Structure and Molecular Polymerization and Induces Potent and Exclusive Th1 Cell Differentiation [PDF]

, 2000
Seigo Korematsu, Yoshimasa Tanaka, Susumu Hosoi, Satoru Koyanagi, Toyokazu Yokota, Bunzo Mikami, Nagahiro Minato   +6 more
openalex   +1 more source

CCN1 Enhances Tumor Immunosuppression through Collagen‐Mediated Chemokine Secretion in Pancreatic Cancer

Advanced Science, EarlyView.
CCN1 modulates the tumor microenvironment in pancreatic cancer by promoting collagen‐dependent chemokine production, thereby facilitating immune evasion. Deletion of CCN1 not only suppresses tumor growth but also enhances immune cell infiltration and increases tumor sensitivity to both chemotherapy and immunotherapy.
Hongjie Fan, Huzi Zhao, Lili Gao, Yucheng Dong, Pei Zhang, Pengfei Yu, Yunfei Ji, Zhe‐Sheng Chen, Xinmiao Liang, Yang Chen   +9 more
wiley   +1 more source