Results 311 to 320 of about 10,689,174 (395)

ALLOGENEIC LIVER-DERIVED DENDRITIC CELL PROGENITORS FAIL TO STIMULATE INTRACELLULAR TH1 CYTOKINE PRODUCTION AND INDUCE ONLY LOW LEVELS OF ANTI-DONOR CTL: ASSOCIATION WITH `SPONTANEOUS' LIVER ALLOGRAFT ACCEPTANCE.

, 1998
Ajai Khanna, Rick Banas, Alison Logar, Angus W. Thomson, Lina Lü   +4 more
openalex   +1 more source

Naive Human T Cells Develop into Th1 Effectors after Stimulation withMycobacterium tuberculosis-Infected Macrophages or Recombinant Ag85 Proteins [PDF]

, 2000
Donna Russo, Н. М. Козлова, David Lakey, Douglas S. Kernodle   +3 more
openalex   +1 more source

MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer

Advanced Science, EarlyView.
This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang, Kexin He, Ruixue Huo, Weihan Li, Shan Zhang, Lu‐Ju Jiang, Hao Wu, Minhao Yu, Shu‐Heng Jiang, Junli Xue   +9 more
wiley   +1 more source

Differential expression of surface Th1 marker (CCR5) and Th2 marker (CRTH2) on infiltrated cells in colonic mucosa of ulcerative colitis

, 2000
Koji Matsuzaki, Ryota Hokari, Shingo Kato, Atsuhiro Iwai, Chie Kurihara, Atsushi Kawaguchi, Shigeaki Nagao, Tohru Miyahara, Kazuro Itoh, Soichiro Miura, Kinya Nagata   +10 more
openalex   +1 more source

Bioengineering Platelets Presenting PD‐L1, Galectin‐9 and BTLA to Ameliorate Type 1 Diabetes

Advanced Science, Volume 12, Issue 16, April 24, 2025.
IFN‐γ‐primed platelets enriched with immunosuppressive ligands (PD‐L1, PD‐L2, BTLA, and Gal‐9) are shown to induce T cell exhaustion and apoptosis, preserving β‐cell function and preventing hyperglycemia progression in type 1 diabetes. IFN‐γ platelets also promote Treg expansion, macrophage polarization, and β‐cell proliferation, offering a promising ...
Yumeng Ma, Fanqiang Meng, Zhongda Lin, Yanjun Chen, Tianyu Lan, Zhaoxin Yang, Rui Diao, Xiaozhou Zhang, Qi Chen, Chi Zhang, Yishi Tian, Chanjuan Li, Wenli Fang, Xin Liang, Xudong Zhang   +14 more
wiley   +1 more source

IL-12 is produced by antigen-presenting cells stimulated with soluble αβ TCR and restores impaired Th1 responses [PDF]

, 2000
Keiko Kawamoto, Vipin Paliwal, Rajani Ramabhadran, Marian Szczepanik, Ryohei Tsuji, Hiroshi Matsuda, Philip W. Askenase   +6 more
openalex   +1 more source

Novel Bivalent mRNA‐LNP Vaccine for Highly Effective Protection against Pneumonic Plague

Advanced Science, EarlyView.
The study investigates mRNA‐lipid nanoparticle vaccines targeting Yersinia pestis, the causative agent of plague. Combined F1+LcrV mRNA vaccination elicited robust immune responses and protected mice against virulent wild‐type and atypical strains.
Uri Elia, Yinon Levy, Hila Cohen, Ayelet Zauberman, David Gur, Inbal Hazan‐Halevy, Moshe Aftalion, Shani Benarroch, Erez Bar‐Haim, Orit Redy‐Keisar, Ofer Cohen, Dan Peer, Emanuelle Mamroud   +12 more
wiley   +1 more source

Author Correction: Co-adjuvanting DDA/TDB liposomes with a TLR7 agonist allows for IgG2a/c class-switching in the absence of Th1 cells. [PDF]

NPJ Vaccines
Zimmermann J, van Haren SD, Diray-Arce J, Adriawan IR, Wørzner K, Krog RT, Guleed S, Hu T, Mortensen R, Dietrich J, Solbak SMØ, Levy O, Christensen D, Pedersen GK.   +13 more
europepmc   +1 more source

T-regulatory-1 (TR1) cells prevent colitis induced by enteric bacterial antigen-reactive pathogenic TH1 cells

, 2000
Yingzi Cong, Casey T. Weaver, Audrey J. Lazenby, John P. Sundberg, Charles O. Elson   +4 more
openalex   +1 more source

Harnessing Photocycloreversion for Dimer Construction and Photoactivation: From Molecule to Aggregate

Aggregate, EarlyView.
State‐dependent luminescence is achieved by utilizing the photocycloreversion of a series of phenanthrene cycloadducts and their parent phenanthrene molecules, which includes freely emissive monomer and quenched excimer in solution, as well as constrained emissive monomer and nonclassical emissive excimer in aggregate.
Zeyang Ding, Bo Wu, Zonghang Liu, Haoran Wang, Feng Gao, Xilong Wei, Zheng Zhao, Parvej Alam, Zijie Qiu, Ben Zhong Tang   +9 more
wiley   +1 more source