Results 121 to 130 of about 22,410 (257)

A case of thoracic disk herniation in Th2/3.

, 1989
Akira Harada, Kaoru Yoshioka, Hisashi Ueda, Yoshikazu Ikuta, Masahiro Harada   +4 more
openalex   +2 more sources

Activation of STAT Proteins and Cytokine Genes in Human Th1 and Th2 Cells Generated in the Absence of IL-12 and IL-4 [PDF]

, 1998
Richard Moriggl, Colette Kristofic, B Kinzel, Siniša Volarević, Bernd Groner, Volker Brinkmann   +5 more
openalex   +1 more source

YC‐4‐3, a Novel Glycogen Synthase Kinase 3β Inhibitor, Alleviates the Endoplasmic Reticulum Stress of Macrophages in Primary Immune Thrombocytopenia

Advanced Science, Volume 12, Issue 17, May 8, 2025.
A patented GSK‐3β inhibitor (GSK‐3βi), new benzothiazepinone compounds (BTZs), YC‐4‐3, can modulate the inflammatory status of macrophages in primary immune thrombocytopenia (ITP), and improve the thrombocytopenia in murine ITP models by directly interacting with endoplasmic reticulum (ER) stress response.
Pengcheng Xu, Lili Ji, Yanxia Zhan, Yang Ou, Xia Shao, Xibing Zhuang, Fanli Hua, Feng Li, Hao Chen, Yong Chu, Yunfeng Cheng   +10 more
wiley   +1 more source

Ca2+ signaling in T-cell subsets with a focus on the role of Cav1 channels: Possible implications in therapeutics.

Frontiers in Immunology, 2013
Lucette ePelletier, M. eSavignac
doaj   +1 more source

Persistent infiltration of CD45RC?CD4+ T cells, Th2-like effector cells, in prolonging hepatic allografts in rats pretreated with a donor-specific blood transfusion [PDF]

, 1997
N Miyanari, Yasuo Yamaguchi, Kenjiro Matsuno, A Tominaga, M Goto, Osamu Ichiguchi, K Mori, Minetaro Ogawa   +7 more
openalex   +1 more source

A Spleen‐Targeted Tolerogenic mRNA‐LNPs Vaccine for the Treatment of Experimental Asthma

Advanced Science, Volume 12, Issue 13, April 3, 2025.
Splenic DCs‐targeted co‐delivery of nucleoside‐modified antigen mRNA and Cel‐loaded LNPs vaccine induces tolerogenic DCs and subsequent antigen‐specific CD4+ regulatory T cells for the treatment of experimental allergic asthma. Abstract Lipid nanoparticles (LNPs)‐based mRNA vaccines have witnessed their great advantages in the fight against infectious ...
Fazhan Wang, Jia Lou, Xiaohan Lou, Fang Wu, Xiaoke Gao, Xiaohan Yao, Jiajia Wan, Xixi Duan, Wenjing Deng, Lixia Ma, Lijing Zhang, Guangjie He, Ming Wang, Chen Ni, Ningjing Lei, Zhihai Qin   +15 more
wiley   +1 more source

Verteporfin‐Mediated In Situ Nanovaccine Based on Local Conventional‐Dose Hypofractionated Radiotherapy Enhances Antitumor and Immunomodulatory Effect

Advanced Science, EarlyView.
Here gelatinase‐responsive methoxypolyethyleneglycol–PVGLIG–polycaprolactone (mPEG–PVGLIG–PCL) nanoparticles’ loading verteporfin (N@VP) is developed, enhancing radiotherapy via X‐ray‐triggered singlet oxygen generation. Combined with 2 Gy (gray, a radiation dose unit) irradiation, N@VP achieves antitumor efficacy comparable to 8 Gy, and also promotes ...
Zhifan Zhang, Lin Li, Yuchen Ge, Anni Chen, Shanchao Diao, Yueling Yang, Qianyue Chen, Yingling Zhou, Jie Shao, Fanyan Meng, Lixia Yu, Manman Tian, Xiaoping Qian, Zhaoyu Lin, Chen Xie, Baorui Liu, Rutian Li   +16 more
wiley   +1 more source

The Innate Immune Sensor Zbp1 Mediates Central Nervous System Inflammation Induced by Angiostrongylus Cantonensis by Promoting Macrophage Inflammatory Phenotypes

Advanced Science, Volume 12, Issue 11, March 20, 2025.
This study reveals that Zbp1 plays a pivotal role in regulating neuroimmune interactions during Angiostrongylus cantonensis (AC) infection. Zbp1 modulates lymphocyte infiltration and natural killer (NK) cell cytotoxicity by promoting cytokine secretion and M1 polarization of macrophages, shaping the CNS immune microenvironment.
Hongli Zhou, Minyu Zhou, XiPing Liao, Liangyu Zhang, Hang Wei, Yuting Lu, Yiqing Zhang, Hui Huang, Yue Hu, Tao Chen, Zhiyue Lv   +10 more
wiley   +1 more source

Cloning of TH0- and TH2-type helper lymphocytes from liver granulomas of Schistosoma mansoni-infected mice

, 1994
Yi‐Chun Zhu, Nicholas W. Lukacs, Dov L. Boros   +2 more
openalex   +1 more source

Transforming Growth Factor β (TGF-β)-dependent Inhibition of T Helper Cell 2 (Th2)-induced Autoimmunity by Self–Major Histocompatibility Complex (MHC) Class II–specific, Regulatory CD4+ T Cell Lines [PDF]

, 1997
Frank Bridoux, Abdallah Badou, Abdelhadi Saoudi, I Bernard, E Druet, Régine Pasquier, Philippe Druet, Lucette Pelletier   +7 more
openalex   +1 more source