Results 201 to 210 of about 223,069 (306)

Serum Eosinophil Level Correlates With Atopic Dermatitis Severity: A Multicenter Cross‐Sectional Study in Chinese Patients With a Nested Cohort Analysis of Dupilumab Treatment Response

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Personalized treatment strategies for atopic dermatitis (AD) are limited. Although serum total IgE (tIgE) and blood eosinophil levels are proposed biomarkers for AD severity, their clinical utility requires validation. Objectives We aimed to identify biomarkers reflecting AD severity and their association with dupilumab efficacy ...
Zhuying Zhang, Jingwen Xue, Yi Zhao
wiley   +1 more source

From skin to lung: basophil-mediated spread of allergic diseases. [PDF]

Front Immunol
Choi ED, Voehringer D, Radtke D.
europepmc   +1 more source

Not Just Mycosis Fungoides: A Case Series of Concurrent Fungal Infections in Patients With Cutaneous T‐Cell Lymphoma

JEADV Clinical Practice, EarlyView.
ABSTRACT Mycosis fungoides is a misnomer that means ‘mushroom‐like fungal disease’, but it is, in fact, the most common form of cutaneous T‐cell lymphoma. The diagnosis of mycosis fungoides is often delayed due to non‐specific symptoms and cutaneous signs that mimic other common benign inflammatory dermatoses.
Ji Fung Yong, Orla Smith, Claire Quigley, Stephen Crowther, Shyam B. Verma, Kevin Molloy   +5 more
wiley   +1 more source

Th2/Th17 Inflammation: Pathogenic Drivers and Therapeutic Targets in Darier and Hailey‐Hailey Diseases

JEADV Clinical Practice, EarlyView.
Skin samples of Hailey‐Hailey and Darier diseases were analyzed for inflammatory and barrier markers using indirect immunofluorescence and transcriptomic techniques. A mixed Th2/Th17 inflammatory pattern and altered expression of barrier markers were observed.
Ella Glodjajic, Darko Stojkov, Joanna Boros‐Majewska, Jeremy Di Domizio, Michel Gilliet, Christoph Schlapbach, Timothée Fettrelet, Luca Borradori, Hans‐Uwe Simon, Dagmar Simon, Susanne Radonjic‐Hoesli   +10 more
wiley   +1 more source

Inflammatory Aging-Driven Immune Axis Imbalance and the Mechanisms of Chronicity in Elderly Atopic Dermatitis: A Systematic Review and Meta-Analysis. [PDF]

Immun Inflamm Dis
Wu N, Li Y, Wang X, Wu Y, Yin W.
europepmc   +1 more source

Triggering Receptor Expressed on Myeloid Cells‐2 Regulates Innate Lymphoid Cell Levels in Bleomycin‐Induced Pulmonary Fibrosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Idiopathic pulmonary fibrosis, a pathological change causing poor outcomes, is not reversible despite current antifibrotic therapy. Emerging evidence suggests that innate lymphoid cells (ILCs) mediate lung inflammation and fibrosis after stimulation by endogenous factors.
Hsiao‐Chin Shen, Nien‐Jung Chen, Chuan‐Yen Sun, Wen‐Kuang Yu, Vincent Yi‐Fong Su, Wan‐Ling Yang, Wei‐Chih Chen, Kuang‐Yao Yang   +7 more
wiley   +1 more source

CD4⁺ T cell subset imbalance contributes to diabetic kidney disease progression: immunopathological mechanisms and targeted therapeutic strategies. [PDF]

Front Immunol
Zheng D, Zhang L, Li H, Wang D, Jiao C, Li X, Fu S.   +6 more
europepmc   +1 more source

Trends in the Asthma Burden Attributable to High Body Mass Index in Children Across 204 Countries and Territories, 1990–2021: An Analysis of the 2021 Global Burden of Disease Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT High body mass index (BMI) has been identified as a significant risk factor for childhood asthma. Given the rising prevalence of childhood obesity, assessing the impact of high BMI on asthma burden trends is imperative. Utilizing Global Burden of Disease (GBD) data, we estimated age‐, sex‐, geography‐, and sociodemographic index (SDI ...
Hua Li, Hai‐Yan Chen, Dong‐Zhi Zheng, Qiu‐Yi Liu, Jia‐Bing Li   +4 more
wiley   +1 more source

Regulatory T-cell-biased IL-2 mutein inhibits development of allergen-specific T_H2 cells and allergic asthma. [PDF]

J Allergy Clin Immunol
Selle A, Yero A, Moon JJ, Campbell DJ, Luster AD.   +4 more
europepmc   +1 more source

A genetic model for development, physiology and behavior of catecholamine-deficient zebrafish larvae. [PDF]

Commun Biol
Paredes-Zúñiga S, Veit R, Østevold K, Arrey G, Wehrle J, Frank D, Oswald J, Veit F, Schredelseker T, Glauben S, Holzschuh J, Driever W.   +11 more
europepmc   +1 more source