Results 221 to 230 of about 320,350 (302)

[Niranthin ameliorates Crohn's disease-like colitis in mice via antagonizing intestinal epithelial cell apoptosis and regulating intestinal Th1/Th2 immune homeostasis]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Wen H, Lin J, Zuo L, Liu M.
europepmc   +1 more source

Age‐related clinical heterogeneity and peripheral T cell profile alterations in primary Sjögren's disease: A retrospective study of 5778 patients

Rheumatology &Autoimmunity, EarlyView.
This large‐scale retrospective study of 5778 primary Sjögren's disease (SjD) patients, stratified by diagnostic age, defines a distinct clinical and immunological profile for early‐diagnosed (<45 years) disease. We identified early diagnosis as an independent risk factor for hypergammaglobulinemia and interstitial lung disease, underpinned by a ...
Yuan Ning, Ruiling Feng, Kai Zhang, Yipeng Han, Ruoyi Wang, Guangwen Li, Yuebo Jin, Jing He   +7 more
wiley   +1 more source

Novel Therapeutics for Chronic Obstructive Pulmonary Disease: From Empirical Bronchodilation to Precision Medicine

Respirology, EarlyView.
ABSTRACT Chronic obstructive pulmonary disease (COPD) remains the third leading cause of death worldwide, and conventional bronchodilator‐based therapies have limited efficacy in preventing exacerbations and disease progression. The 2024–2026 period represents a historic inflection point: three mechanistically distinct agents received Food and Drug ...
Naoya Fujino, Hisatoshi Sugiura
wiley   +1 more source

An integrated immunopathological model of syphilis serofast: a systematic review and meta-analysis. [PDF]

Front Immunol
Zeng YX, Yang L, He YY, Deng ZL, Ke WJ, Wang HY.   +5 more
europepmc   +1 more source

Teachers' Pedagogical Reasoning and Students' Three‐Dimensional Learning

Science Education, EarlyView.
ABSTRACT This article reports analyses of data from a design‐based implementation project focused on middle‐ and high‐school science teaching. Drawing on teacher interviews and surveys as well as student learning evidence, we examined the relationships between teachers' pedagogical reasoning and their students' three‐dimensional learning. Most teachers
Christie Morrison Thomas, Beth A. Covitt, Qinyun Lin, Stefanie L. Marshall, James B. Hancock II, Charles W. Anderson   +5 more
wiley   +1 more source

Nicotine Suppresses Human Memory Th Cell Subsets With Preferential Effects on Central Memory Th Cells in an α7 Nicotinic Acetylcholine Receptor-Dependent Manner. [PDF]

Eur J Immunol
Gholizadeh F, Hajiaghayi M, Rahbari N, Choi JS, Heidt S, Como A, Kazerouni M, Kargar M, Pinard-LaRoche A, Shih SCC, Darlington PJ.   +10 more
europepmc   +1 more source

Robust Bioconjugated Antigens Induce Immune Responses Preventing Malaria Infection and its Transmission

Small, EarlyView.
Engineered malaria antigens enable in vivo bioconjugation to submicron biopolymer particles in E. coli. Two antigens are co‐tethered at high density and defined stoichiometry. The resulting thermostable particles elicit strong, durable antibody and T‐cell responses, conferring robust protection and blocking mosquito transmission.
Nivethika Sivakumaran, Yevel Flores‐Garcia, Chanel M. Naar, Shuxiong Chen, Mili Mehta, Fijs W. B. van Leeuwen, Abhai Tripathi, Rajagopal Murugan, Meta Roestenberg, Fidel Zavala, Bernd H. A. Rehm   +10 more
wiley   +1 more source

Coinfection with malaria alters the fecundity and within-host persistence of an intestinal nematode. [PDF]

PLoS Negl Trop Dis
Bourbon L, Dusuel A, Groetz E, Rialland M, Roche B, Faivre B, Sorci G.   +6 more
europepmc   +1 more source

Beyond Th2, more than ILC2

Allergology International, 2017
openaire   +3 more sources

Moment‐curvature behavior of continuous reinforced concrete slab strips—Experimental determination and modeling

Structural Concrete, EarlyView.
Abstract With the market introduction of new reinforcing materials, such as corrosion‐resistant steel, the effect of their stress–strain relationship on the ductility of reinforced concrete structures needs to be evaluated. Their moment‐curvature behavior significantly influences bending moment redistributions, rotation capacity, and deformation at ...
Nathalie Reckinger, Karel Thoma, Walter Kaufmann   +2 more
wiley   +1 more source