Results 221 to 230 of about 170,157 (266)

Coemergence of Insomnia and a Shift in the Th1/Th2 Balance toward Th2 Dominance

Neuroimmunomodulation, 2002
<i>Objectives:</i> Insomnia is associated with physical and mental disorders. We examined the effect of insomnia on immune functions, focusing on the T helper 1 (Th1)/ T helper 2 (Th2) balance, by a cross-sectional design. <i>Methods:</i> We provided a self-administered questionnaire to evaluate sleep habits, smoking and medical
Shotaro, Sakami, Toshio, Ishikawa, Norito, Kawakami, Takashi, Haratani, Akira, Fukui, Fumio, Kobayashi, Osamu, Fujita, Shunichi, Araki, Noriyuki, Kawamura   +8 more
openaire   +2 more sources

Markers of Th1 and Th2 Cells

1996
Markers of TH1 and TH2 lymphocyte subpopulations.
ALMERIGOGNA, FABIO, D'ELIOS, MARIO MILCO, DE CARLI M., DEL PRETE, GIANFRANCO   +3 more
openaire   +4 more sources

A disproportion of TH1/TH2 cytokines with predominance of TH2, in urothelial carcinoma of bladder

Urologic Oncology: Seminars and Original Investigations, 2011
Bladder cancer is a common tumor of the urinary tract, accounting for 6% to 8% of all male malignancies and 2% to 3% of all female malignancies. Urothelial carcinoma (UC) of bladder is the second most common urologic malignancy after prostate cancer. Earlier report has elucidated immunologic unreactivity in cancer patients.
Abhigyan, Satyam, Prabhjot, Singh, Nitika, Badjatia, Amlesh, Seth, Alpana, Sharma   +4 more
openaire   +2 more sources

Signaling pathways in Th2 development

Immunological Reviews, 2004
Summary:  In order for an immune response to be successful, it must be of the appropriate type and magnitude. Intracellular residing pathogens require a cell‐mediated immune response, whereas extracellular pathogens evoke a humoral immune response. T‐helper (Th) cells orchestrate the immune response and are divided into two subsets, Th1 and Th2 cells ...
Kerri A, Mowen, Laurie H, Glimcher
openaire   +2 more sources

The Th2 Cytokine Environment of the Placenta

International Archives of Allergy and Immunology, 2000
It is now accepted that local changes to the balance of Th1/Th2-type cytokines occur during pregnancy within the maternal uterus and fetoplacental unit. These changes in cytokine profiles contribute to implantation of the embryo, development of the placenta, and survival of the fetus to term.
G B, Dealtry, M K, O'Farrell, N, Fernandez   +2 more
openaire   +2 more sources

Th1/Th2 Cross Regulation

Journal of Theoretical Biology, 1994
We present and analyze a model for the cross-regulation of the Th1 and Th2 helper cell subsets during an immune response by the regulatory cytokines interferon-gamma (IFN)-gamma) and interleukin-10 (IL-10). IFN-gamma, secreted by Th1 cells, can inhibit the proliferation of Th2 cells.
M A, Fishman, A S, Perelson
openaire   +2 more sources

The Th1/Th2 balance in autoimmunity

Current Opinion in Immunology, 1995
The study of autoimmune disease in the context of T-helper type 1 (Th1) and T-helper type 2 (Th2) CD4+ T-cell responses demonstrates that the relative contribution of either T-cell type to the development of a particular autoimmune response can influence whether or not this response leads to clinical disease.
B, Charlton, K J, Lafferty
openaire   +2 more sources

NLRP3 moonlights in TH2 polarization

Nature Immunology, 2015
As the cytosolic guardian for many microbial and sterile inflammatory insults, NLRP3 is best appreciated for its innate immunological role mediating inflammasome activation. Now NLRP3 debuts as a transcription factor key for TH2 polarization.
Jenny P Y Ting, Jonathan A Harton
openaire   +2 more sources

TH2 cell development and function

Nature Reviews Immunology, 2017
T helper 2 (TH2) cells orchestrate protective type 2 immune responses, such as those that target helminths and facilitate tissue repair, but also contribute to chronic inflammatory diseases, such as asthma and allergy. Here, we review recent insights into how diverse molecular signals from cellular sources, including dendritic cells, innate lymphoid ...
Jennifer A, Walker, Andrew N J, McKenzie
openaire   +2 more sources

Th1/Th2 balance in infection

Springer Seminars in Immunopathology, 1999
Cytokines produced by T helper (Th) cells are of critical importance for the outcome of many infectious diseases. Producing the "right" set of cytokines in response to an infectious agent can be a matter of life or death. The Th1/Th2 dichotomy, although an oversimplification has proven useful in the analysis of immune responses to infections.
C, Infante-Duarte, T, Kamradt
openaire   +2 more sources