Results 241 to 250 of about 223,069 (306)

Integrative Analysis of Plasma Proteome and Genome Reveals Novel Drug Targets for Chronic Rhinosinusitis and Nasal Polyps

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou   +4 more
wiley   +1 more source

From first contact to challenge: Lung immune modulation by single-sex Schistosoma mansoni infections. [PDF]

open access: yesPLoS Negl Trop Dis
Bischofsberger M   +5 more
europepmc   +1 more source
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Th2 cell-derived histamine is involved in nasal Th2 infiltration in mice

Inflammation Research, 2021
Histamine derived from mast cells and basophils plays important roles in inducing allergic symptoms. Although T cells also produce histamine, the involvement of the histamine produced from T cells has remained enigmatic. We sought to reveal the roles of T helper 2 (Th2) cell-derived histamine in nasal allergic disorders.The histamine production from ...
Naruhito Iwasaki   +6 more
openaire   +2 more sources

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