Results 231 to 240 of about 170,157 (266)
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Nature Immunology, 2015
Optimal immunosuppression by regulatory T cells (Treg cells) relies on gene-expression and signaling modules that are customized to the target cell. The kinase CK2 is upregulated in Treg cells and controls a newly identified Treg cell subset that acts on dendritic cells to suppress T helper type 2 inflammatory responses in the lungs.
Deepali V, Sawant, Alexander L, Dent
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Optimal immunosuppression by regulatory T cells (Treg cells) relies on gene-expression and signaling modules that are customized to the target cell. The kinase CK2 is upregulated in Treg cells and controls a newly identified Treg cell subset that acts on dendritic cells to suppress T helper type 2 inflammatory responses in the lungs.
Deepali V, Sawant, Alexander L, Dent
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Th1/Th2 balance in preeclampsia
Journal of Reproductive Immunology, 2003The syndrome of preeclampsia has previously been ascribed to generalized maternal endothelial dysfunction, poor placentation and excessive maternal inflammatory response. Recent reports suggest that preeclampsia is associated with a Th1 predominant profile and may be considered as a failure of the tolerance system allowing the second physiological ...
Shigeru, Saito, Masatoshi, Sakai
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Clinical Immunology and Immunopathology, 1996
A large body of evidence suggests the existence of functionally polarized human T cell responses based on their profile of cytokine secretion in both the CD4+ T helper (Th) and the CD8+ T cytotoxic (Tc) cell subset. Human Th1 and Th2 cells not only produce a different set of cytokines but also exhibit distinct functional properties and the preferential
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A large body of evidence suggests the existence of functionally polarized human T cell responses based on their profile of cytokine secretion in both the CD4+ T helper (Th) and the CD8+ T cytotoxic (Tc) cell subset. Human Th1 and Th2 cells not only produce a different set of cytokines but also exhibit distinct functional properties and the preferential
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Redirecting Th2 Responses in Allergy
1999Atopic diseases are genetically determined disorders which affect approximately 20%–30% of the general population in developed countries and whose prevalence is increasing over the last decades. They are characterized by an enhanced ability of B lymphocytes to produce IgE antibodies in response to certain groups of otherwise innocuous environmental ...
PARRONCHI, PAOLA +2 more
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Annals of the New York Academy of Sciences, 1996
TH2-type cytokines, particularly interleukin-5, together with granulocyte-macrophage colony-stimulating factor and interleukin-3, orchestrate the eosinophil response in asthma. Eosinophils are believed to be prime proinflammatory effector cells causing bronchial damage, which in turn, leads to chronic asthma symptoms.
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TH2-type cytokines, particularly interleukin-5, together with granulocyte-macrophage colony-stimulating factor and interleukin-3, orchestrate the eosinophil response in asthma. Eosinophils are believed to be prime proinflammatory effector cells causing bronchial damage, which in turn, leads to chronic asthma symptoms.
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Asthma phenotyping: TH2-high, TH2-low, and beyond
Journal of Allergy and Clinical Immunology, 2014Sterk, Peter J., Lutter, René
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IL-6 prevents Th2 cell polarization by promoting SOCS3-dependent suppression of IL-2 signaling
Cellular and Molecular Immunology, 2023Holly Bachus +2 more
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