Results 101 to 110 of about 8,035 (194)

Rôle de l'axe TH17/TH22 dans la régulation de la réponse immune dans l'asthme allergique

, 2013
L'asthme allergique est caractérisé par une réponse prédominante de typeTh2, mais d'autres profils tels que Th17 et Th22 sont aussi observés dans l'asthme plus sévère.
Fan, Ying
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A novel, dual cytokine-secretion assay for the purification of human Th22 cells that do not co-produce IL-17A

, 2015
BACKGROUND Interleukin-22 is produced by certain T helper cells subsets (Th17, Th22) and at lower levels by γ-δ T cells, NKT and innate lymphoid cells. Th22 cells are unique immune cells that regulate tissue responses by IL-22 production.
C. A. Akdis, M. Wawrzyniak, Ochsner, U, Wirz, O, U. Ochsner, O. Wirz, W. van de Veen, Akdis, C A, Wawrzyniak, P, Wawrzyniak, M, van de Veen, W, Akdis, M, P. Wawrzyniak, M. Akdis, Ochsner U, Akdis M, van de Veen W, Akdis CA, Wawrzyniak P, Wawrzyniak M, Wirz O   +20 more
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The Newly Identified T Helper 22 Cells Lodge in Leukemia

International Journal of Hematology-Oncology and Stem Cell Research, 2015
Leukemia is a hematological tumor in which the malignant myeloid or lymphoid subsets play a pivotal role. Newly identified T helper cell 22 (Th22) is a subset of CD4(+) T cells with distinguished gene expression, function and specific properties apart ...
Gholamreza Azizi, Mohsen Rastegar Pouyani, Shadi Sadat Navabi, Reza Yazdani, Fatemeh Kiaee, Abbas Mirshafiey   +5 more
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Increased percentages of Th22 cells in peripheral blood from MHO and T2D patients and their correlation with Th1/Th17 frequencies.

, 2014
Circulating percentages of Th22, Th1, and Th17 cells from CTLs, MHO, and T2D patients. (A) Significantly increased percentages of Th22 cells in MHO (1.88±0.10%) and T2D patients (2.247±0.10%) as compared to CTLs (1.18±0.06 ...
Li Chen (5749), Jun Song (19318), Xinguo Hou (510458), Shounan Yi (510456), Dongqi Tang (136130), Peng Lin (251745), Ruxing Zhao (510455), Chuanlong Wu (506770), Yiran Lu (510457), Wenjuan Li (308527), Lei Sun (45752)   +10 more
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Aryl hydrocarbon receptor (AhR) ligation by VAF347 promotes Th22 and inhibits Th1 polarization.

, 2012
The Aryl hydrocarbon receptor (AhR) is a transcription factor implicated in human and murine Th22 polarization, which does not notably influence the expression of IL-17 in mice.
Rubio, Manuel, Regairaz, Camille, Sarfati, Marika, Carballido, Jose, Kenins, Linda, Woisetchlager, Maximilian, Baba, Nobuyasu   +6 more
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特应性皮炎患者外周血中Th22、Treg细胞及其细胞因子表达的研究

Zhongguo shiyan zhenduanxue, 2019
目的检测特应性皮炎(AD)患者外周血中辅助性T细胞22(Th22)和调节性T细胞(Treg)及其细胞因子IL-22和TGF-β的表达,探讨其与AD发病之间的关系及临床意义。方法选择52例AD患者,按照欧洲特应性皮炎评分标准(SCORAD)进行评分分组;使用流式细胞仪检测52例AD患者和和20例健康人Th22和Treg细胞的数量;用酶联免疫吸附法(ELISA)检测血清中IL-22和TGF-β的表达。结果与对照组比较,AD患者外周血中Th22细胞的比例及血清中IL-22的水平显著增高 ...
李志, 杨婷婷, 李文哲
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Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling.

, 2009
Th subsets are defined according to their production of lineage-indicating cytokines and functions. In this study, we have identified a subset of human Th cells that infiltrates the epidermis in individuals with inflammatory skin disorders and is ...
Eyerich, Stefanie;Eyerich, Kilian;Pennino, Davide;Carbone, Teresa;Nasorri, Francesca;Pallotta, Sabatino;Cianfarani, Francesca;Odorisio, Teresa;Traidl-Hoffmann, Claudia;Behrendt, Heidrun;Durham, Stephen R.;Schmidt-Weber, Carsten B.;Cavani, Andrea, Eyerich, S;Eyerich, K;Pennino, D;Carbone, T;Nasorri, F;Pallotta, S;Cianfarani, F;Odorisio, T;Traidl-Hoffmann, C;Behrendt, H;Durham, SR;Schmidt-Weber, CB;Cavani, A   +1 more
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Repertoire-based mapping and time-tracking of T helper cell subsets in scRNA-Seq

Frontiers in Immunology
IntroductionThe functional programs of CD4+ T helper (Th) cell clones play a central role in shaping immune responses to different challenges. While advances in single-cell RNA sequencing (scRNA-Seq) have significantly improved our understanding of the ...
Daniil K. Lukyanov, Daniil K. Lukyanov, Valeriia V. Kriukova, Kristin Ladell, Irina A. Shagina, Irina A. Shagina, Dmitry B. Staroverov, Dmitry B. Staroverov, Bella E. Minasian, Anna S. Fedosova, Pavel Shelyakin, Oleg N. Suchalko, Alexander Y. Komkov, Konstantin A. Blagodatskikh, Kelly L. Miners, Olga V. Britanova, Olga V. Britanova, Olga V. Britanova, Andre Franke, David A. Price, David A. Price, Dmitry M. Chudakov, Dmitry M. Chudakov, Dmitry M. Chudakov, Dmitry M. Chudakov, Dmitry M. Chudakov   +25 more
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Role of Th22 cells in Helicobacter pylori-related gastritis and peptic ulcer diseases

, 2019
Helicobacter pylori (H. pylori) has been shown to be one of the leading causes of peptic ulcer diseases (PUDs) and gastritis. T helper-22 (Th22) cells and its most important cytokine, interleukin-22 (IL-22) are importantly active in inflammation and ...
Shafigh, Mohammadhadi, Haghighian, Mehrnoosh, Soltani, Amin, Bagheri, Nader, Sanaii, Ahmad, Tahmasbi, Kamran, Rahimian, Ghorbanali, Shirzad, Hedayatollah   +7 more
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Th22 Cells in the liver – functional interaction with hepatocytes in an alcohol-dominated micromilieu

, 2016
In dieser Arbeit konnte gezeigt werden, dass es unter den aus einer Alkohol-induzierten zirrhotischen Leber stammenden T-Zellen eine konstante Population an Th-22 Zellen gibt und dass diese mit den IL-22-Rezeptor-exprimierenden Hepatozyten spezifisch ...
Böhner, Alexander
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