Results 231 to 240 of about 4,912,109 (290)

From analytical to data‐driven: multi‐method optimization of a bendable mirror system for dynamic focusing

Journal of Synchrotron Radiation, EarlyView.
A small‐radius‐of‐curvature bendable mirror system is developed for dynamic focusing in X‐ray free‐electron laser and synchrotron radiation beamlines, and a transfer‐learning neural‐network and differential‐evolution framework is used for force‐to‐shape modeling and inverse optimization.
Baoning Sun, Zhixiang Wen, Qinghao Zhu, Jun Luo, Tairong Xu, Lingfeng Zhu, Yaxiang Liang, Jitao Sun, Zhuo Li, Shun Xia, Zhongmin Xu, Meiyi Wu, Qinming Li, Weiqing Zhang, Xueming Yang   +14 more
wiley   +1 more source

Time‐resolved coherent X‐ray scattering analysis of nanorod colloids: dynamics and photon‐statistical effects in angular X‐ray cross‐correlation analysis

Journal of Synchrotron Radiation, EarlyView.
A statistical framework combining angular X‐ray cross‐correlation analysis, principal component analysis and photon‐counting simulations is presented for evaluating the detectability of orientational fluctuations in time‐resolved coherent X‐ray scattering experiments.Understanding the dynamic fluctuations of anisotropic particles is essential for ...
Taiki Hoshino, Yoshifumi Amamoto, Takahiro Mikami, Yoshiaki Honjo, Kyosuke Ozaki, Toshiyuki Nishiyama Hiraki, Haruki Nishino, Yasumasa Joti, Takaki Hatsui, Yoshiki Kohmura, Takashi Kato   +10 more
wiley   +1 more source

Dupilumab‐Associated Erythema Multiforme‐Like Eruption With Lichenoid Histology in a Paediatric Patient: A Case Report

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Dupilumab‐associated erythema multiforme and lichenoid eruptions have been previously reported as rare dermatological adverse events. We present an atypical paediatric case of a dupilumab‐associated erythema multiforme‐like eruption in a 5‐year‐old male eczema patient, who developed erythematous targetoid papules and plaques over the upper and
Paul Sun Woo Kim, Jacqueline Tu, Kelvin Truong, Gloria Fong, William Luu, Narinder Kaur, Miriam Fewtrell, Li‐Chuen Wong   +7 more
wiley   +1 more source

Dupilumab in Paediatric Netherton Syndrome: Two Case Reports and a Review of the Literature

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Netherton Syndrome (NS) is a rare genodermatosis characterised by a triad of ichthyosiform erythroderma, an atopic diathesis, and trichorrhexis invaginata, for which no effective management is currently approved in Australia. Dupilumab has demonstrated considerable effectiveness in the treatment of atopic conditions in the paediatric ...
Jacqueline Tu, Paul Sun Woo Kim, Kelvin Truong, Gloria Fong, William Luu, Li‐Chuen Wong   +5 more
wiley   +1 more source

Autosomal Dominant Hyper‐IgE Syndrome Patients Retain IL10‐Producing preTh17‐Cells That Are Activated by Opportunistic Pathogens and Support IgE Production

Allergy, EarlyView.
IL‐10 producing CCR6+Th‐cells are central memory T‐cells that express ROR‐γt and differentiate to Th17‐cells via an autocrine loop of STAT3‐activating cytokines (preTh17). STAT3‐deficient AD‐HIES patients lack Th17‐ and Tfh17‐cells but retain preTh17‐ and Th1/17‐cells.
Giorgia Moschetti, Chiara Vasco, Francesca Clemente, Paola Larghi, Sara Maioli, Edoardo Scarpa, Elena Carelli, Nadia Pulvirenti, Maria Lucia Sarnicola, Mariacristina Crosti, Manal Bel Imam, Willem van de Veen, Loris Rizzello, Sergio Abrignani, Lucia A. Baselli, Rosa Maria Dellepiane, Maria Carrabba, Giovanna Fabio, Jens Geginat   +18 more
wiley   +1 more source

Author Correction: Cutaneous T cell lymphoma atlas reveals malignant T_H2 cells supported by a B cell-rich tumor microenvironment. [PDF]

Nat Immunol
Li R, Strobl J, Poyner EFM, Balbaa A, Torabi F, Mazin PV, Chipampe NJ, Stephenson E, Ramírez-Suástegi C, Shanmugiah VBM, Gardner L, Olabi B, Coulthard R, Botting RA, Zila N, Prigmore E, Gopee NH, Chroscik MA, Kritikaki E, Engelbert J, Goh I, Chan HM, Johnson HF, Ellis J, Rowe V, Tun W, Reynolds G, Yang D, Foster AR, Gambardella L, Winheim E, Admane C, Rumney B, Steele L, Jardine L, Nenonen J, Pickard K, Lumley J, Hampton P, Hu S, Liu F, Liu X, Horsfall D, Basurto-Lozada D, Grimble L, Bacon CM, Weatherhead SC, Brauner H, Wang Y, Bai F, Reynolds NJ, Allen JE, Jonak C, Brunner PM, Teichmann SA, Haniffa M.   +55 more
europepmc   +1 more source

CD4+ T Cell‐Intrinsic Arg1 Regulates Th1 Dynamics in Influenza: Functional and Translational Implications for Infection and Cancer Inflammation

Allergy, EarlyView.
Anishaa Balaji, Sophia N. Karagiannis, Alexandra J. McCraw   +2 more
wiley   +1 more source

Nematode in Cockroaches: A Potential Allergen Source

Allergy, EarlyView.
Dongjun Kang, Myung‐hee Yi, Jun Ho Choi, Yun Soo Jang, Seongjun Choe, Ju Yeong Kim   +5 more
wiley   +1 more source

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Th2 Cells in Health and Disease

Annual Review of Immunology, 2017
Helper T (Th) cell subsets direct immune responses by producing signature cytokines. Th2 cells produce IL-4, IL-5, and IL-13, which are important in humoral immunity and protection from helminth infection and are central to the pathogenesis of many allergic inflammatory diseases.
Damon Tumes, Yoshitaka Okamoto, Toshinori Nakayama   +2 more
exaly   +4 more sources

Th1 and Th2 cells

Current Opinion in Hematology, 2001
After activation, CD4 helper T (Th) cells differentiate into Th1or Th2 effector subsets. These two types of cells produce distinct profiles of cytokines and regulate different immune responses. This review summarizes recent progress on different features of co-stimulatory regulation and chemokine-mediated homing of Th1 and Th2 cells.
C, Dong, R A, Flavell
openaire   +2 more sources