Results 1 to 10 of about 107,712 (298)

Update in Laboratory Diagnosis of Thalassemia

Frontiers in Molecular Biosciences, 2020
Alpha- and β-thalassemias and abnormal hemoglobin (Hb) are common in tropical countries. These abnormal globin genes in different combinations lead to many thalassemic diseases including three severe thalassemia diseases, i.e., homozygous β-thalassemia ...
Thongperm Munkongdee, Ping Chen, Pranee Winichagoon, Suthat Fucharoen, Kittiphong Paiboonsukwong   +4 more
doaj   +2 more sources

Publisher’s Note: Page Numbers Changed to Article Numbers for Articles Published in Thalassemia Reports Volumes 1–11

Thalassemia Reports, 2022
From Volume 1 (2011) to Volume 11 (2021), Thalassemia Reports [...]
Thalassemia Reports Editorial Office
doaj   +1 more source

Disorders of the erythrocyte membrane

Italian Journal of Medicine, 2015
Hemolytic anemia due to abnormalities of the erythrocyte membrane comprises an important group of inherited disorders. These include hereditary spherocytosis, hereditary elliptocytosis, hereditary pyropoikilocytosis, and the hereditary stomatocytosis ...
Sophia Delicou, Aikaterini Xydaki, Chryssanthi Kontaxi, Konstantinos Maragkos   +3 more
doaj   +1 more source

Increased autophagy leads to decreased apoptosis during β-thalassaemic mouse and patient erythropoiesis

Scientific Reports, 2022
β-Thalassaemia results from defects in β-globin chain production, leading to ineffective erythropoiesis and subsequently to severe anaemia and other complications.
Pornthip Chaichompoo, Ramaneeya Nithipongvanitch, Wasinee Kheansaard, Alisa Tubsuwan, Kanitta Srinoun, Jim Vadolas, Suthat Fucharoen, Duncan R. Smith, Pranee Winichagoon, Saovaros Svasti   +9 more
doaj   +1 more source

Prevalence of iron overload complications among patients with β-thalassemia major treated at Dubai Thalassemia Centre

Annals of Saudi Medicine, 2013
BACKGROUND AND OBJECTIVES: Authors and team members of the Dubai Thalassemia Centre obtained data on the prevalence of iron overload complications among patients with β-thalassemia major (β-TM) and compared it to international data to improve patient ...
Khawla Mohammed Belhoul, Maisan Lateef Bakir, Ahmed Mohamed Kadhim, Hany ElSayed Dewedar, Mohamed Salah Eldin, Fatheya Abbas AlKhaja   +5 more
doaj   +1 more source

Coinheritance of the c.-19 G > C and c.315 + 1 G > A Variants in the β-Globin Gene Leads to Thalassemia Disease: A Report from the North of Iran

Case Reports in Genetics, 2023
Up to now, more than 300 pathogenic variants have been identified in the β-globin gene, some of which are categorized as silent mutations that do not change the hematological indices.
Hossein Jalali, Mahan Mahdavi, Mohammad Eslamijouybari, Mohammad Reza Mahdavi   +3 more
doaj   +1 more source

Fertility in Patients with Thalassemia and Outcome of Pregnancies: A Turkish Experience

Turkish Journal of Hematology, 2019
Objective: In recent years, the rates of marriage and pregnancy are increasing in patients with thalassemia major. The aim of the present study was to investigate the fertility rate of thalassemic patients and the course of pregnancies in terms of mother
Burcu Akıncı, Akkız Şahin Yaşar, Nihal Özdemir Karadaş, Zuhal Önder Siviş, Hamiyet Hekimci Özdemir, Deniz Yılmaz Karapınar, Can Balkan, Kaan Kavaklı, Yeşim Aydınok   +8 more
doaj   +1 more source

Noninvasive prenatal screening test for compound heterozygous beta thalassemia using an amplification refractory mutation system real-time polymerase chain reaction technique

Hematology Reports, 2019
We propose using a modified amplification refractory mutation system real-time polymerase chain reaction (ARMS RTPCR) technique to exclude the invasive prenatal diagnosis for a non-paternally inherited beta thalassemia mutation in couples atrisk for ...
Narutchala Suwannakhon, Tanapat Pangeson, Teerapat Seeratanachot, Khwanruedee Mahingsa, Arunee Pingyod, Wanwipa Bumrungpakdee, Torpong Sanguansermsri   +6 more
doaj   +1 more source

Bromhexine is a potential drug for COVID-19; From hypothesis to clinical trials

Вопросы вирусологии, 2022
COVID-19 (novel coronavirus disease 2019), caused by the SARS-CoV-2 virus, has various clinical manifestations and several pathogenic pathways. Although several therapeutic options have been used to control COVID-19, none of these medications have been ...
S. Bahadoram, B. Keikhaei, M. Bahadoram, M.-R. Mahmoudian-Sani, S. Hassanzadeh, A. Saeedi-Boroujeni, K. Alikhani   +6 more
doaj   +1 more source

An overview of complications associated with deferoxamine therapy in thalassemia [PDF]

Journal of Nephropharmacology, 2021
Thalassemic syndromes are the most common genetic diseases in the world that are related to blood transfusion and iron overload in the body. In ß-thalassemia major multiple blood transfusions due to ineffective erythropoiesis lead to iron excess in the ...
Bijan Keikhaei, Neda Farmani-Anooshe, Mohammad Bahadoram, Mohammad-Reza Mahmoudian-Sani, Kosar Alikhani, Ammar Helalinasab   +5 more
doaj   +1 more source