Results 91 to 100 of about 219,391 (317)

Arthrospira platensis and Chlorella vulgaris Consumption on Iron Status: A Systematic Review of In Vivo Studies

Molecular Nutrition &Food Research, EarlyView.
This graphical abstract provides a comparative overview of the mechanisms by which Arthrospira platensis and Chlorella vulgaris exert their effects. It highlights significant differences in their biological pathways, molecular interactions, and physiological effects, providing a clear visual summary.
Alexandra Lacurezeanu, Dan Cristian Vodnar   +1 more
wiley   +1 more source

A human complement receptor 1 polymorphism that reduces Plasmodium falciparum rosetting confers protection against severe malaria [PDF]

, 2003
Parasitized red blood cells (RBCs) from children suffering from severe malaria often adhere to complement receptor 1 (CR1) on uninfected RBCs to form clumps of cells known as "rosettes." Despite a well documented association between rosetting and severe ...
A. O'Donnell, Ahearn, Allen, Allen, Carlson, Carlson, Carlson, Cattani, Chong, Cockburn, Cohen, David, Dervillez, Flint, Herrera, Ho, I. A. Cockburn, J. A. Rowe, J. C. Reeder, J. M. Moulds, Jarolim, Kaul, Kumar, Luzzi, Luzzi, M. Baisor, M. Bockarie, M. J. Mackinnon, Miller, Moldenhauer, Molthan, Moulds, Moulds, Nagayasu, Nash, Pascual, Ringwald, Rowe, Rowe, Rowe, Rowe, S. J. Allen, Soubes, Udomsangpetch, Weisman, White, Wilson, Xiang, Zhang, Zimmerman   +49 more
core   +2 more sources

The prevalence of thalassemia in mainland China: evidence from epidemiological surveys

Scientific Reports, 2017
Comprehensive data regarding the epidemiology and prevalence of thalassemia in mainland China are lacking. To assess the prevalence of thalassemia, we performed a meta-analysis including 16 articles published from 1981 to 2015.
Ketong Lai, Guifeng Huang, Li Su, Yunyan He   +3 more
semanticscholar   +1 more source

Heterozygous Beta‐Thalassaemia in Pregnancy: Two Rare Causes of Severe Fetal Anemia Requiring Intrauterine Blood Transfusions

Prenatal Diagnosis, EarlyView.
ABSTRACT Aim In this article, we present two cases of severe fetal hemolytic anemia based on a beta‐thalassaemia trait inherited from a single parent. Results These cases, presented at 20 and 28 weeks' gestation, necessitated intra‐uterine blood transfusions.
Eva van der Meij, Frans J. W. Smiers, Tamara T. Koopmann, Ingrid Krapels, Kaatje LePoole, Enrico Lopriore, Johanna M. Middeldorp, Claudia S. Ootjers, Volkher Scharnhorst, Hubertina C. J. Scheepers, Cornelis L. Harteveld, E. J. T. (Joanne) Verweij   +11 more
wiley   +1 more source

PB2240: SILENT GLOBIN MUTATIONS. 10 YEARS REFERRALS FOR GENETIC COUNSELING.

HemaSphere, 2022
S. Theodoridou, A. Teli, E. Boutou, E.-E. Delaki, E. Yfanti, V. Efthimia, E. Zarkada, A. Balassopoulou   +7 more
doaj   +1 more source

Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis

Prenatal Diagnosis, EarlyView.
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell, Samantha Stover, Nora Gibson, Timothy Olson, James Connelly, Matthew Grace, Jennifer Andrews   +6 more
wiley   +1 more source

PB2541: RARE CAP +41 TO +44 [HBB:C.11_-8DELAAAC]/NI MUTATION IN THE 5;UTR OF THE Β GLOBIN GENE IN A GREEK MALE AND GENETIC COUNSELING.

HemaSphere, 2023
Stamatia Theodoridou, Evaggelia-Eleni Delaki, Eleni Yfanti, Aikaterini Teli, Genovefa Mantzou, Christina Karipidou, Maria Dimopoulou   +6 more
doaj   +1 more source

Minihepcidins are rationally designed small peptides that mimic hepcidin activity in mice and may be useful for the treatment of iron overload [PDF]

, 2011
Iron overload is the hallmark of hereditary hemochromatosis and a complication of iron-loading anemias such as β-thalassemia. Treatment can be burdensome and have significant side effects, and new therapeutic options are needed.
Alan Waring, Bo Qiao, Elizabeta Nemeth, Emilio Ramos, Fujita, Gloria C. Preza, Gualdi, Kearney, Lyskov, Michael A. Peralta, Nemeth, Piotr Ruchala, Porter, Rogelio Pinon, Sham, Shantanu Sharma, Tomas Ganz   +16 more
core   +2 more sources

Correction of β-thalassemia mutant by base editor in human embryos

Protein & Cell, 2017
β-Thalassemia is a global health issue, caused by mutations in the HBB gene. Among these mutations, HBB −28 (A>G) mutations is one of the three most common mutations in China and Southeast Asia patients with β-thalassemia.
Puping Liang, C. Ding, Hongwei Sun, Xiaowei Xie, Yanwen Xu, Xiya Zhang, Ying Sun, Y. Xiong, Wenbin Ma, Yongxiang Liu, Yali Wang, Jianpei Fang, Dan Liu, Z. Songyang, Canquan Zhou, Junjiu Huang   +15 more
semanticscholar   +1 more source

Gene Mutation Spectrum of Thalassemia Among Children in Yunnan Province

Frontiers in Pediatrics, 2020
Background: Thalassemia is an autosomal genetic disorder, found throughout the world. It is still not treatable and create socio economic problems. In this study, we investigated the prevalence and spectrum features of thalassemia in Yunnan Province, the
Tilong Huang, Tiancheng Zhang, Chun-yan Song, Yunbi Lin, Bao-Hua Sang, Qing-ling Lei, Yu Lv, Chunhui Yang, Na Li, Xin Tian, Yue-huang Yang, Xian‐Wen Zhang   +11 more
semanticscholar   +1 more source