Results 111 to 120 of about 219,391 (317)

Rapid Serological Detection of Anti‐GM‐CSF Autoantibodies in Autoimmune Pulmonary Alveolar Proteinosis Using a Novel Immunochromatographic Test

open access: yesRespirology, EarlyView.
We developed a novel ICT with high clinical performance that can distinguish APAP patients from those with other pulmonary diseases. The rapid and simple detection of GMAbs in serum provided a new practical method for the diagnosis of APAP. ABSTRACT Background and Objectives Anti‐GM‐CSF autoantibodies (GMAbs) are essential biomarkers for diagnosing ...
Chika Narita   +10 more
wiley   +1 more source

Prevalence and intensity of depression in mothers of children with beta-thalassemia major in Talghani Hospital of Gorgan, Iran [PDF]

open access: yes, 2014
Background: Thalassemia is a chronic disease that it leads to psychological and social problems for parents. Mothers are at markedly increased risk of suffering from psychological distress and depression because they usually take on a considerable part ...
Jahazi, A.   +3 more
core  

Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components

open access: yesSmall Methods, EarlyView.
The review presents a comprehensive overview of each component of lipid nanoparticles(LNPs)and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu   +6 more
wiley   +1 more source

The Effect of Resveratrol on Gamma Globin Gene Expression in Patients with Beta Thalassemia: The Role of Adaptation to Cellular Stress

open access: yesThalassemia Reports
HbF induction is an appropriate strategy to ameliorate the severity of β-thalassemia symptoms. Hydroxyurea (HU) is the most common chemical agent introduced as an HbF inducer but responsiveness to HU is variable and the introduction of HbF inducers ...
Hossein Jalali   +5 more
doaj   +1 more source

Fast-track strategy for the prevention of Hb Bart’s hydrops fetalis syndrome

open access: yesThalassemia Reports, 2017
We propose a fast-track strategy [direct blood DNA analysis using a quantitative real-time polymerase chain reaction (PCR) technique] for the early risk detection and prenatal diagnosis of α(0)-thalassemia (SEA and Thai deletion).
Narutchala Suwannakhon   +7 more
doaj   +1 more source

Perceptions of thalassemia and its treatment among Malaysian thalassemia patients: A qualitative study [PDF]

open access: yes, 2016
Background Thalassemia is a common public health problem in Malaysia and one of the most common chronic and genetic disorders. Aims The present qualitative study explores knowledge about thalassemia, perceptions about conventional therapies and the ...
Ahmad Hassali, Mohamed Azmi   +4 more
core   +2 more sources

Awareness about thalassemia in post graduate students

open access: yes, 2018
Inherited hemoglobinopathies are basically thalassemia syndromes that occur due to decreased or absent formation of normal hemoglobin. Abnormal globin gene in thalassemia describes its type.
M. Qadir, M. Rizvi
semanticscholar   +1 more source

How I manage medical complications of β-thalassemia in adults.

open access: yesBlood, 2018
The complex pathophysiology in β-thalassemia can translate to multiple morbidities that affect every organ system. Improved survival due to advances in management means that patients are exposed to the harmful effects of ineffective erythropoiesis ...
A. Taher, M. Cappellini
semanticscholar   +1 more source

Targeted Therapy of Fungal Keratitis Enabled by Iron Nutritional Deprivation Combined With Photothermal Effect

open access: yesSmall Structures, EarlyView.
This work developed a PDC nanoplatform that orchestrated a multimodal synergistic therapy, combining active targeting, photothermal therapy, and iron nutrient deprivation. The antifungal, anti‐inflammatory efficacy and corneal repair ability of nanoplatform were demonstrated through both in vitro and in vivo evaluations.
Ruojiao Feng   +13 more
wiley   +1 more source

Inherited thrombocytopenias: Early diagnosis for optimum treatment

open access: yesPediatric Hematology Oncology Journal, 2022
Anagha Kulkarni   +7 more
doaj   +1 more source

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