Results 71 to 80 of about 107,712 (298)

Gene Mutation Spectrum of Thalassemia Among Children in Yunnan Province

Frontiers in Pediatrics, 2020
Background: Thalassemia is an autosomal genetic disorder, found throughout the world. It is still not treatable and create socio economic problems. In this study, we investigated the prevalence and spectrum features of thalassemia in Yunnan Province, the
Tilong Huang, Tiancheng Zhang, Chun-yan Song, Yunbi Lin, Bao-Hua Sang, Qing-ling Lei, Yu Lv, Chunhui Yang, Na Li, Xin Tian, Yue-huang Yang, Xianwen Zhang   +11 more
semanticscholar   +1 more source

A comprehensive review on adaptive plasticity and recovery mechanisms post‐acquired brain injury

Neuroprotection, EarlyView.
This figure illustrates the dynamic process of neurogenesis following brain injury, focusing on the roles of neural stem and progenitor cells at the injury site. Key mechanisms include axonal sprouting, synaptogenesis, dendritic remodeling, and brain‐derived neurotrophic factor signaling via TrkB receptors.
Ravi Kumar Rajan
wiley   +1 more source

Oral ferroportin inhibitor ameliorates ineffective erythropoiesis in a model of β-thalassemia.

Journal of Clinical Investigation, 2019
β-thalassemia is a genetic anemia caused by partial or complete loss of β-globin synthesis leading to ineffective erythropoiesis and RBCs with short life-span.
V. Manolova, N. Nyffenegger, A. Flace, P. Altermatt, Ahmet Varol, C. Doucerain, Hanna Sundstrom, F. Dürrenberger   +7 more
semanticscholar   +1 more source

Classification of thalassemia data using random forest algorithm

Journal of Physics: Conference Series, 2020
Thalassemia is a blood disorder that occurred in Southeast Asia. Thalassemia cannot be cured, but early detected thalassemia with screening process is the best way to prevent thalassemia disease.
F. Aszhari, Zuherman Rustam, F. Subroto, A. S. Semendawai   +3 more
semanticscholar   +1 more source

Gas Chromatography‐Mass Spectrometry Analysis, Genoprotective, and Antioxidant Potential of Curio radicans (L. f.) P.V. Heath

ChemistryOpen, EarlyView.
The ethyl acetate extract of Curio radicans is found to contain a higher proportion of bioactive compounds (55% vs 30% in the ethanolic extract) by gas chromatography‐mass spectrometry, and it exhibits stronger antioxidant activity in the DPPH assay (75% vs 65% inhibition) as well as clear genoprotective effects against H2O2‐induced DNA damage ...
Muhammad Naseer, Muhammad Adil, Sarir Ahmad, Mikhlid H. Almutairi, Abdulwahed Fahad Alrefaei, Sajid Ali, Fayaz Asad   +6 more
wiley   +1 more source

Heterozygous Beta‐Thalassaemia in Pregnancy: Two Rare Causes of Severe Fetal Anemia Requiring Intrauterine Blood Transfusions

Prenatal Diagnosis, EarlyView.
ABSTRACT Aim In this article, we present two cases of severe fetal hemolytic anemia based on a beta‐thalassaemia trait inherited from a single parent. Results These cases, presented at 20 and 28 weeks' gestation, necessitated intra‐uterine blood transfusions.
Eva van der Meij, Frans J. W. Smiers, Tamara T. Koopmann, Ingrid Krapels, Kaatje LePoole, Enrico Lopriore, Johanna M. Middeldorp, Claudia S. Ootjers, Volkher Scharnhorst, Hubertina C. J. Scheepers, Cornelis L. Harteveld, E. J. T. (Joanne) Verweij   +11 more
wiley   +1 more source

Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis

Prenatal Diagnosis, EarlyView.
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell, Samantha Stover, Nora Gibson, Timothy Olson, James Connelly, Matthew Grace, Jennifer Andrews   +6 more
wiley   +1 more source

Molecular Epidemiology and Hematologic Characterization of Thalassemia in Guangdong Province, Southern China

Clinical and Applied Thrombosis/Hemostasis, 2022
Introduction: About 2% of the population in the world are carriers of the thalassemia gene. Thalassemia is highly prevalent in Southern China, and traditional clinical testing methods would cause missed diagnosis of partial static thalassemia.
Jiajia Xian MD, Yanchao Wang MD, Jianchun He MD, Shaoying Li MD, Wenzhi He MD, Xiaoyan Ma MD, Qing Li PhD   +6 more
doaj   +1 more source

Awareness about thalassemia in post graduate students

, 2018
Inherited hemoglobinopathies are basically thalassemia syndromes that occur due to decreased or absent formation of normal hemoglobin. Abnormal globin gene in thalassemia describes its type.
M. Qadir, M. Rizvi
semanticscholar   +1 more source

Refractory anaemia in a patient with end‐stage heart failure secondary to aortic stenosis

ESC Heart Failure, EarlyView.
Jiayu Liang, Suxin Luo, Bi Huang
wiley   +1 more source