Results 121 to 130 of about 4,949,451 (244)
The Primary Reasons People Participate in Maternal‐Fetal Phase I Clinical Trials Are Psychosocial
ABSTRACT Recent critiques of ethical guidance for maternal‐fetal therapy clinical trials has highlighted the need to weigh maternal, fetal, and societal interests, respectively, while deprioritizing psychosocial reasons for participation. Psychosocial reasons refer to the psychological and social influences on study participants’ decisions, and they ...
Julia E. H. Brown +6 more
wiley +1 more source
Pregnancy in women with thalassemia: challenges and solutions
George Petrakos, Panagiotis Andriopoulos, Maria Tsironi Department of Nursing, University of Peloponnese, Sparta, Greece Abstract: Advances in treatment of thalassemia have led to the aging of thalassemic patients, and consequently concern about ...
Andriopoulos P, Petrakos G, Tsironi M
core
The study assessed the demographic and nutritional profiles of children aged 2–5 years with and without thalassemia carrier status in Belkuchi, Sirajganj, Bangladesh. Thalassemia carrier children had significantly lower height‐for‐age z‐scores (HAZ), indicating poorer linear growth.
Sabuktagin Rahman +3 more
wiley +1 more source
The history of beta-thalassemia in Turkey
The first two patients with beta-thalassemia major in Turkey, were reported in 1941. However, the importance of beta-thalassemia as a health problem was brought to the attention of physicians only after 1950.
M Aksoy
doaj
Intratumoral and Peritumoral Functional Connectivity Reveals Network‐Level Signatures of Glioma
Using resting‐state fMRI in 306 glioma patients, this study maps individualized intra‐ and peritumoral functional networks. Novel metrics (RIFR, RPTR) quantify tumor‐related network remodeling, correlating with pathology, structure, cognition, and survival. A prognostic model incorporating these network features achieves an AUC of 0.90.
Hongbo Bao +24 more
wiley +1 more source
Mental health status in patients with Thalassemia major in Iran
Thalassemia major is a genetic blood disorder that is detected by the symptoms of chronic and severe anemia, enlarged liver and spleen, failure to thrive and bone deformities in particular deformed face and bulging forehead.
Soheila Shahmohammadi +2 more
core +1 more source
Background: Heart disease is the main cause of mortality and morbidity in patients with beta thalassemia, rendering its early diagnosis vital. We studied and compared echocardiographic findings in patients with beta thalassemia major, patients with beta ...
Noormohammad Noori +5 more
doaj
β‐Thalassemia intermedia exhibits distinct region‐specific molecular patterns shaped by three interacting genetic axes: β‐globin mutation severity, HbF‐inducing modifiers, and α‐globin gene dosage. Mediterranean populations are predominantly mutation‐driven, Middle Eastern populations rely on HbF compensation, and Asian populations are governed by ...
Kavindya Fernando +2 more
wiley +1 more source
The role of iron in normal and impaired testicular function
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer +2 more
wiley +1 more source

