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Classical meets malignant hematology: a case of acquired εγδβ-thalassemia in clonal hematopoiesis [PDF]
HaematologicaHemoglobinopathies including thalassemias are among the most frequent genetic disorders worldwide. Primarily, these entities result from germline variants in the globin gene clusters and their cis-acting regulatory elements, and thus the WHO classifies ...
Armin P. Piehler +9 more
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Incidence Trends of Inherited Anemias at the Global, Regional, and National Levels Over Three Decades [PDF]
Journal of Epidemiology and Global Health, 2023 Inherited anemia continues to pose a significant public health concern on a global scale, owing to its extensive geographical prevalence, substantial patient population, and profound ramifications.
Hongwei Tang +6 more
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Thalassemia, a human blood disorder
Brazilian Journal of Biology, 2021 A group of inherited blood defects is known as Thalassemia is among the world’s most prevalent hemoglobinopathies. Thalassemias are of two types such as Alpha and Beta Thalassemia. The cause of these defects is gene mutations leading to low levels and/or
F. Shafique +8 more
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Trends in Pediatrics, 2021 Defects in protein structure or synthesis of hemoglobin are called hemoglobinopathies. Thalassemia is the most common hemoglobinopathy, and it is estimated that 5% of the world population carries at least one variant allele of thalassemia.
Tekin Aksu, Sule Unal
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Arresting rampant dental caries with silver diamine fluoride in a young teenager suffering from chronic oral graft versus host disease post-bone marrow transplantation: a case report [PDF]
, 2014 BACKGROUND: Rampant caries is an advanced and severe dental disease that affects multiple teeth. This case describes the management of rampant caries in a young teenager suffering from chronic oral graft versus host disease after allogeneic bone marrow ...
Chan, GCF +4 more
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Thalassemias in South Asia: clinical lessons learnt from Bangladesh
Orphanet Journal of Rare Diseases, 2017 Thalassemias are emerging as a global public health concern. Due to remarkable success in the reduction of childhood mortality by controlling infectious diseases in developing countries, thalassemias are likely to be a major public health concern in the ...
Mohammad Sorowar Hossain +12 more
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Oro-dental clinical aspects in children with thalassemia [PDF]
Archives of the Balkan Medical Union, 2019 Introduction. Thalassemias are the most common monogenic diseases. They are divided in two major categories: alpha – thalassemias (minor thalassemia), that do not have a special symptomatology and beta-thalassemias, which are a form of hereditary disease
Andrei KOZMA +4 more
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Prevalence and genotypes of α- and β-thalassemia carriers in Hong Kong - Implications for population screening [PDF]
, 1997 Background: The thalassemias are common in southern China. We determined the prevalence of heterozygous carriers of these genetic disorders in Hong Kong and assessed the feasibility of a community-based screening program.
Chan, LC +6 more
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Recent advances in gene therapy for thalassemia
Journal of Pharmacy and Bioallied Sciences, 2012 Thalassemias are genetically transmitted disorders. Depending upon whether the genetic defects or deletion lies in transmission of α or β globin chain gene, thalassemias are classified into α and β-thalassemias.
J V Raja, M A Rachchh, R H Gokani
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Thalassemia Reports, 2014 ENERCA (the European Network for Rare and Congenital Anemias) is a European Commission funded project since 2002. Rare anaemias in Europe comprise haemoglobin disorders, such as thalassemias or sickle cell disease, and other rarer disorders, including ...
Patricia Aguilar-Martínez
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