Results 151 to 160 of about 5,799 (244)

Decrease in α-Globin and Increase in the Autophagy-Activating Kinase ULK1 mRNA in Erythroid Precursors from β-Thalassemia Patients Treated with Sirolimus. [PDF]

Int J Mol Sci, 2023
Zurlo M, Zuccato C, Cosenza LC, Gasparello J, Gamberini MR, Stievano A, Fortini M, Prosdocimi M, Finotti A, Gambari R.   +9 more
europepmc   +1 more source

Recent Insights Into Circulating Adipokines in Obesity: Systematic Review and Meta‐Analysis

Obesity Science &Practice, Volume 12, Issue 1, February 2026.
ABSTRACT Background Adipokines are dysregulated in obesity and exacerbate proinflammatory conditions. Although several studies have investigated adipokine levels in obesity, their findings have been inconsistent, leaving the precise nature of these alterations uncertain.
Sunita Sunita, Mohammad Ghozali, Mohammad Rizki Akbar, Annisa Dewi Nugrahani, Iis Inayati Rakhmat, Siti Nur Fatimah, Yuni Susanti Pratiwi, Eko Fuji Ariyanto, Gaga Irawan Nugraha, Mas Rizky A. A. Syamsunarno, Tri Hanggono Achmad   +10 more
wiley   +1 more source

Rapid Serological Detection of Anti‐GM‐CSF Autoantibodies in Autoimmune Pulmonary Alveolar Proteinosis Using a Novel Immunochromatographic Test

Respirology, Volume 31, Issue 2, Page 184-192, February 2026.
We developed a novel ICT with high clinical performance that can distinguish APAP patients from those with other pulmonary diseases. The rapid and simple detection of GMAbs in serum provided a new practical method for the diagnosis of APAP. See related editorial ABSTRACT Background and Objectives Anti‐GM‐CSF autoantibodies (GMAbs) are essential ...
Chika Narita, Kenjiro Shima, Jun‐ichiro Sekiguchi, Yasuyuki Ozeki, Makoto Akiwa, Shohei Koike, Sachiko Yuki, Keiichi Akasaka, Toshiaki Kikuchi, Nobutaka Kitamura, Koh Nakata   +10 more
wiley   +1 more source

Is Ferroptosis the Mechanistic Bridge Connecting Iron Dysregulation to Muscle Wasting and Functional Decline in Aging?

Aging Cell, Volume 25, Issue 2, February 2026.
This work proposes ferroptosis as a mechanistic driver of age‐related muscle dysfunction, whereby iron dyshomeostasis and impaired antioxidant capacity promote lipid peroxidation, and eventually trigger ferroptosis, leading to muscle wasting, and ultimately contributing to weakness and functional decline with aging.
Rola S. Zeidan, Simon Reinhard, Anna Picca, Emanuele Marzetti, Christiaan Leeuwenburgh, James F. Collins, Stephen D. Anton   +6 more
wiley   +1 more source

Identification of maternal ^Gγ(^Aγδβ)⁰ thalassemia through retrospective reanalysis of prenatal cfDNA sequencing data. [PDF]

Ann Med
Zhu X, Hu L, Pei Y, Ran J, Wen L, Zhong J, Zhu Y, Zeng K, Wei F, Liu W.   +9 more
europepmc   +1 more source

Endocrine gland abnormalities in thalassemia major: A brief review

, 2003
Thalassemia major (β-thalassemia) affects a significant segment of the population in certain areas of the world. Alterations in migration patterns have changed the geographic distribution of this disease and made it a worldwide health problem.
Bazrafshan, H.R., Mohammadian, S., Sadeghi-Nejad, A.   +2 more
core  

Comparative efficacy of varicocelectomy and intrauterine insemination in varicocoele patients with mild semen abnormalities: An observational study

Andrology, Volume 14, Issue 2, Page 487-495, February 2026.
Abstract Background Varicocoele is a common cause of male infertility, affecting spermatogenesis through increased testicular temperature, venous stasis, and oxidative stress. Microsurgical subinguinal varicocelectomy improves semen quality, whereas intrauterine insemination is widely used for mild male factor infertility.
Yanlin Ma, Weiming Deng, Tingting Wu, Qi Li, Yuanjie Li, Wenjie Mai, Lizheng Yan, Changwei Liang, Lingxiao Zhang   +8 more
wiley   +1 more source

A Mass Spectrometry-Based Multiplexed Targeted Assay for Detection of Hemoglobinopathies from Dried Blood Spots. [PDF]

J Mol Diagn
Bellad A, Rangiah K, Chavan S, Warade J, Das B, Pandey A.   +5 more
europepmc   +1 more source

Prevalence of Severe Thalassemia and Performance of Prenatal Screening Tests Among Pregnant Women at Siriraj Thalassemia Center in Thailand

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Severe thalassemia remains a significant public health concern in Southeast Asia. Prenatal screening is an effective strategy for early detection and prevention. This study aimed to determine the prevalence of severe thalassemia and assess the performance of prenatal screening at the Siriraj Thalassemia Center, Siriraj Hospital, Thailand.
Kwandao Malasai, Usa Chaikledkaew, Pattarawalai Talungchit, Sitaporn Youngkong, Wanvisa Udomsinprasert, Chanin Limwongse, Jiraphun Jittikoon   +6 more
wiley   +1 more source

Response to Comment on: "A case series of patients with β-thalassemia trait and iron overload: from multifactorial hepcidin suppression to treatment with miniphlebotomies". [PDF]

Haematologica
Busti F, Girelli D.
europepmc   +1 more source