Results 51 to 60 of about 3,873 (265)
Frequency of Sensory Neural Hearing Loss in Major Beta-Thalassemias in Southern Iran [PDF]
, 2011 Objective: The thalassemias are among the most common genetic disorders worldwide, occurring more frequently in the Mediterranean region. The aim of this study was to determined frequency of sensory-neural hearing loss in major β- thalassemias ...
Faramarzi, Abolhassan +4 more
core +2 more sources
Journal of the Scientific Society, 2014 This article provides an insight towards diagnosing and managing thalassemias. It begins by describing the structure of normal hemoglobin and elaborates on our understanding of the pathophysiology of thalassemia.
Ramesh Aggarwal +2 more
doaj +1 more source
Invasive and Noninvasive Approaches in Prenatal Diagnosis of Thalassemias
, 2018 Thalassemia is a significant health problem worldwide. There are two main classifications, α- and β-thalassemias, which are usually caused by the defective synthesis of the α-globin, and which are commonly caused by different mutations of the β-globin ...
Tuli, Abdullah +3 more
core +1 more source
JPGN Reports, EarlyView.Abstract Plummer–Vinson syndrome (PVS) is characterised by the triad of dysphagia, iron‐deficiency anaemia, and proximal oesophageal webs. While well described in adults, paediatric cases remain exceptionally rare, particularly in sub‐Saharan Africa.
Paul Mike Tayou Mbobda +2 more
wiley +1 more source
Evaluation Of Novel Biomarkers For Early Detection Of Acute Kidney Injury In Children With B-Thalassemia Major [PDF]
Zagazig University Medical JournalBackground: Improved survival in patients with β-thalassemia has enabled the appearance of several clinical morbidities, involving renal problems. Incredibly important is the early detection of persons at higher risk of getting renal failure. Aim of work:
mohamed mostafa +3 more
doaj +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Advances in therapy have extended the life expectancy of patients with thalassemia to near that of the general population; complications such as endocrine disorders and osteoporosis remain prevalent. This study aimed to identify endocrine complications, factors associated with endocrine complications, and changes in bone mineral density (BMD ...
Cheng‐Ying Hsu +7 more
wiley +1 more source
Control of thalassemia in India
Thalassemia Reports, 2014 The β-thalassemias and sickle cell disorders pose a major health burden in the large and diverse Indian population. Education programs for awareness generation are being done by National Institutions, non-governmental organizations and Thalassemia ...
Roshan B. Colah, Ajit Gorakshakar
doaj +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Neurodegeneration with Brain Iron Accumulation (NBIA) is a heterogeneous group of heritable, mostly recessive, progressive neurodegenerative diseases characterized by iron deposition in the basal ganglia and brainstem. There are no solid global epidemiological data on prevalence and incidence of NBIA subtypes, but registry data and ...
Susanne A. Schneider +3 more
wiley +1 more source
Applied Sciences, 2019 Screening programs for genetic and metabolic diseases such as haemoglobinopathies, thalassemias and diabetes are a worldwide problem that faces economic and technological limitations.
Ricardo J. Pais +5 more
doaj +1 more source
Neuroprotection, EarlyView.Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji +4 more
wiley +1 more source