Results 131 to 140 of about 67,878 (296)
Ethical Issues in the Drug Approval Process [PDF]
, 2013 The Food and Drug Administration’s (FDA) drug approval process carries great significance for both pharmaceutical companies and for patients. In recent decades, there has been a shift towards expedited approval so that drugs, especially those for ...
McInnis, Meghan
core +1 more source
Defects and Disabilities of Thalidomide Children [PDF]
, 1973 R. W. Smithells
openalex +1 more source
When Autoimmunity Meets Malignancy: A Rare Case of Concomitant Systemic Lupus and Multiple Myeloma
Clinical Case Reports, Volume 14, Issue 1, January 2026.ABSTRACT The association between systemic lupus erythematosus (SLE) and multiple myeloma (MM) is rare, with fewer than 20 cases reported in the literature, raising questions about the link between chronic immune dysregulation and oncogenesis. We report the case of a 43‐year‐old Malagasy woman in whom a monoclonal β2‐globulin spike, incidentally ...
Solohery Jean Noël Ratsimbazafy +7 more
wiley +1 more source
Thalidomide: A novel therapy for microsporidiosis [PDF]
, 1997 D Sharpstone +6 more
openalex +1 more source
ChemMedChem, Volume 21, Issue 1, January 2026.The design, synthesis, and initial biological evaluation of noncovalent stimulator of interferon genes degraders are presented. The lead from this series, BH690L, exhibits an effective concentration for half‐maximal degradation (DC50) of 11.3 nM and a maximum level of degradation (Dmax) of 0.67.
Bo Hu, Adam S. Duerfeldt
wiley +1 more source
Old Drugs, New Opportunities: Advancing Cancer Care Through Repurposing
United European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
Norman R. Williams
wiley +1 more source
Ethics &Human Research, Volume 48, Issue 1, Page 2-11, January–February 2026.ABSTRACT Leading medical organizations have called for advancement of pregnancy‐specific research to reduce harmful evidence gaps. However, meeting this objective poses ethical, legal, and policy dilemmas for investigators, oversight committees, academic institutions, and sponsors.
Anne Drapkin Lyerly +8 more
wiley +1 more source
Navigating the evolving management of smoldering multiple myeloma
HemaSphere, Volume 10, Issue 1, January 2026.Abstract Smoldering multiple myeloma (SMM) represents an intermediate clinical stage between monoclonal gammopathy of undetermined significance (MGUS) and symptomatic multiple myeloma (MM). SMM carries a highly variable risk of progression to MM, requiring individualized risk stratification to guide management.
M. Bakri Hammami +6 more
wiley +1 more source
A Rational Approach to Pharmacotherapy in Pregnancy
The Journal of Clinical Pharmacology, Volume 66, Issue 1, January 2026.Abstract Most pregnant individuals are exposed to at least one medication, whether prescription or over the counter, during pregnancy. Despite the ubiquity of medication use in pregnancy, there remains no standardized framework to guide clinicians in selecting the most appropriate pharmacotherapy that balances maternal needs with fetal safety. This gap
Gregory W. Kirschen +2 more
wiley +1 more source