Results 61 to 70 of about 54,104 (311)
Scientific ReportsStudies of (S)-thalidomide were conducted on zebrafish embryos subjected to electroporation processes using a square wave pulse generator. The results showed that the electroporation increases the absorption of (S)-thalidomide through the chorion into ...
Anna Małkowska +7 more
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Thalidomide alleviated IgA nephropathy through “gut-kidney axis”
Linchuang shenzangbing zazhiObjective Thalidomide has anti-inflammatory, immunomodulatory and renoprotective effects. However, its study in IgA nephropathy has remained scarce. The aim was to explore the role and possible mechanism of thalidomide in IgA nephropathy.
Rui-hua Wang +3 more
doaj +1 more source
Thalidomide in Cancer Treatment
, 2002 There is increased interest in the treatment of cancer with thalidomide because of its antiangiogenic, immunomodulating and sedative effects. In animal models, the antitumour activity of thalidomide is dependent on the species, route of administration ...
Kestell, Philip +7 more
core +1 more source
Essential embryology for the Canadian pathologists’ assistant
Anatomical Sciences Education, EarlyView.Abstract Pathologists' assistants (PAs) are pivotal in healthcare, conducting autopsies and examining tissues under a pathologist's guidance. Embryology knowledge is crucial for PAs to accurately assess anomalies and identify pathologies. Yet, it is often overlooked in academic PA training programs.
Samantha H. Nacci +4 more
wiley +1 more source
Haematologica, 2012 Background Thalidomide has potent antimyeloma activity, but no prospective, randomized controlled trial has evaluated thalidomide monotherapy in patients with relapsed/refractory multiple myeloma.Design and Methods We conducted an international ...
Martin Kropff +17 more
doaj +1 more source
The effect of thalidomide on visceral fat pad mass and triglyceride concentration of the skeletal muscles in rats [PDF]
Yeungnam University Journal of Medicine, 2018 Background Body fats, especially both of abdominal fat pad mass and skeletal muscle fat content, are inversely related to insulin action. Therefore, methods for decreasing visceral fat mass and muscle triglyceride content may be helpful for the ...
Ki-Hoon Kim +2 more
doaj +1 more source
Biomedicine & Pharmacotherapy, 2002 Thalidomide has immunomodulatory and anti-angiogenic properties which may underlie its activity in cancer. After its success in myeloma, it has been investigated in other plasma cell dyscrasias, myelodysplastic syndromes, gliomas, Kaposi's sarcoma, renal cell carcinoma, advanced breast cancer, and colon cancer. Thalidomide causes responses in 30-50% of
S, Singhal, J, Mehta
openaire +2 more sources
Safety of thalidomide and bevacizumab in patients with hereditary hemorrhagic telangiectasia
Orphanet Journal of Rare Diseases, 2019 BackgroundHereditary hemorrhagic telangiectasia (HHT) is a multisystemic inherited vascular dysplasia that leads to nosebleeds and visceral arteriovenous malformations (AVMs).
E. Buscarini +9 more
semanticscholar +1 more source
British Journal of Clinical Pharmacology, EarlyView.Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló +5 more
wiley +1 more source
Canadian Journal of Gastroenterology and Hepatology, 2020 Objective. To observe the effects of thalidomide on 2,4,6-trinitrobenzenesulfonic acid- (TNBS-) induced experimental colitis in rats and to explore the possible mechanism of thalidomide in the treatment of CD. Methods.
Ying Xie +5 more
doaj +1 more source