Second line therapy in malignant pleural mesothelioma: a systematic review [PDF]
, 2015 After the implementation of standard first line chemotherapy with platinum and antifolates in pleural mesothelioma, patients are confronted with a need for second line treatment at relapse or progression.
Baas, Paul +3 more
core +2 more sources
Chiral drugs : one drug or two? : Clinical pharmacology through the looking glass : reflections on the racemate vs enantiomer debate [PDF]
, 1994 Most of the synthetic chiral agents administered as drugs are still marketed as racemic mixtures. Such drug enantiomers can differ substantially in their pharmacological, pharmacokinetic and toxic properties.
Mifsud, Janet
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Hematology Reports, 2017 Angiodysplasia is a frequent cause of persistent gastrointestinal (GI) hemorrhage in elderly patients. Although GI bleeding isn’t the most common manifestation in patients with bleeding disorders, when present, it represents a challenging complication ...
Bruno K.L. Duarte +4 more
doaj +1 more source
Multiple Myeloma : an update on disease biology and therapy [PDF]
, 2004 Multiple myeloma is a malignancy of immunoglobulin producing plasma cells. Clinical features include bone pain due to lytic bone lesions or pathological fractures, anemia, symptomatic hypercalcemia, renal insufficiency, recurrent infections and ...
Cook, Rachel J., Dingli, David
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Regulating Rare Disease: Safely Facilitating Access to Orphan Drugs [PDF]
, 2018 While approximately one in ten Americans suffers from a rare disease, only 5 percent of rare diseases have a U.S. Food and Drug Administration (FDA) approved treatment.
Bannister, Julien B.
core +1 more source
Chemotherapy treatment of multiple myeloma patients increases circulating levels of endothelial microvesicles [PDF]
, 2016 Correspondenc
Adesanya, M. Adeola +5 more
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Thalidomide-induced Bradycardia in an Old Man
International Journal of Gerontology, 2010 We presented a case of an 82-year-old man who had classic Kaposi sarcoma. He took thalidomide 100 mg twice daily for 23 days, and then he felt light-headedness and visited our emergency department.
Ching-Hsueh Tseng +2 more
doaj +1 more source
"The legacy of thalidomide" - A multidisciplinary meeting held at the University of York, United Kingdom, on September 30, 2016 : A multidisciplinary meeting held at the University of York, UK on September 30, 2016 [PDF]
, 2017 BACKGROUND: Between 1957 and 1962 thalidomide was used as a nonaddictive, nonbarbiturate sedative that also was successful in relieving the symptoms of morning sickness in early pregnancy.
Beedie +18 more
core +2 more sources
Clinical Case Reports, 2019 Thalidomide is often used for the management of refractory gastrointestinal angiodysplasia (GIAD). The tolerance, toxic profile, and compliance of thalidomide are dose‐dependent.
Harish Patel +6 more
doaj +1 more source
A National Adverse Drug Reaction Reporting System for Malta [PDF]
, 2004 The mission of the Medicines Authority (MA) in Malta is to contribute to protection of public health through regulation of the safety, quality and efficacy of medicines for human use on the local market and to ensure that healthcare professionals and ...
Arthur, Niamh +2 more
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