Results 171 to 180 of about 42,998 (266)

Effects of nicotinic receptor antagonism on nicotine and THC self-administration in a model of polysubstance use. [PDF]

Int J Neuropsychopharmacol
Torregrossa MM, Racic T, Baglot SL, Stringfield SJ, Hill MN, Sved A.   +5 more
europepmc   +1 more source

In Vitro Metabolism of Δ8‐, Δ9‐, and Δ10‐THC in Human Hepatocytes: Distinct Δ10‐THC Biotransformation and Implications for Drug Testing

Drug Testing and Analysis, Volume 18, Issue 8, Page 1114-1121, August 2026.
Δ8‐THC and Δ9‐THC showed comparable metabolic profiles. In contrast, Δ10‐THC underwent extensive glucuronidation and hydroxylation, with only minor formation of a carboxy metabolite, indicating a markedly different metabolic pathway. These differences may increase the risk of misidentification and misinterpretation in cannabis drug testing.
Robert Kronstrand, Henrik Green, Markus Loh, Fabian Rüttimann, Manuela Carla Monti   +4 more
wiley   +1 more source

The detection of delta-9-tetrahydrocannabinol, delta-8-tetrahydrocannabinol, delta-10-tetrahydrocannabinol, and cannabidiol in hair specimens. [PDF]

J Anal Toxicol
Racines A, Jones J, Lea K, Coy D.
europepmc   +1 more source

Cannabidiol reduces atypical absence seizures and epileptic spasms in a Gabrb3+/D120N mouse model of Lennox–Gastaut syndrome

Epilepsia Open, Volume 11, Issue 4, Page 1263-1275, August 2026.
Abstract Objective Lennox–Gastaut syndrome (LGS) is a drug‐resistant developmental and epileptic encephalopathy (DEE). Preclinical drug development for LGS is constrained by a lack of syndrome‐relevant animal models. We aimed to evaluate a Gabrb3+/D120N knock‐in (KI) mouse model of LGS by quantifying atypical absence seizures and epileptic spasms and ...
Thomas Harman, Laura A. Sharman, Ka Lai Yip, Miguel Bedoya‐Pérez, Vaishali Janve, Jonathon C. Arnold   +5 more
wiley   +1 more source

Recreational substance use and aneurysmal subarachnoid hemorrhage: differential effects of alcohol and THC. [PDF]

Neurosurg Rev
Oppong MD, Witte A, Dammann P, Rexhepi A, Ahmadipour Y, Gümüs M, Li Y, Dinger TF, Rauschenbach L, Deuschl C, Meška D, Sure U, Jabbarli R.   +12 more
europepmc   +1 more source

Genetic architecture of phenological, morphological, and phytochemical traits in Cannabis landraces. [PDF]

Plant Genome
Babaei M, Torkamaneh D.
europepmc   +1 more source

Early and Divergent Lipid Mediator Remodelling in Fast Versus Slow Skeletal Muscles of Female hSOD1G93A Mice

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background Skeletal muscle atrophy in amyotrophic lateral sclerosis (ALS) drives loss of muscle strength, function and quality of life in ALS patients. The endocannabinoid system (ECS) regulates muscle homeostasis via regenerative and metabolic processes, and although ECS alterations have been reported in ALS neural tissues, ECS remodelling ...
Sebastiaan Dalle, Kaat Vanderbeke, Thibaut Burg, Moniek Schouten, Wout Lauriks, Nicole Hersmus, Ludo Van Den Bosch, Katrien Koppo   +7 more
wiley   +1 more source

The acute and chronic pharmacokinetics and pharmacodynamics of oral cannabidiol with and without low doses of delta-9-tetrahydrocannabinol. [PDF]

J Anal Toxicol
Wolinsky D, Zamarripa CA, Spindle TR, Klausner M, Cone EJ, Winecker RE, Vikingsson S, Flegel RR, Hayes ED, Davis LS, Kuntz D, Bonn-Miller M, Bigelow GE, Vandrey R.   +13 more
europepmc   +1 more source

Supercritical Angle Fluorescence and Raman Techniques in Biophotonics

Laser &Photonics Reviews, Volume 20, Issue 15, 7 August 2026.
Supercritical angle fluorescence (SAF) microscopy and supercritical angle Raman (SAR) spectroscopy have emerged as powerful tools in the field of biophotonics, enabling high‐resolution imaging and spectroscopy of biological specimens near interfaces. This review article provides a comprehensive overview of the principles, techniques, applications, and ...
Subir Das, Nathalia Simea Münch, Stefan Seeger   +2 more
wiley   +1 more source

Rapid LC-QTOF-MS screening method for semi-synthetic cannabinoids in whole blood. [PDF]

J Anal Toxicol
Schirmer W, Walton SE, Weinmann W, Schürch S, Logan BK, Krotulski AJ.   +5 more
europepmc   +1 more source