Results 171 to 180 of about 45,377 (263)

The Development of a Simple Liquid Chromatography‐Precursor Ion Scan‐Mass Spectrometry Screening Method for the Detection of Phytocannabinoids in Plant Extracts [PDF]

J Mass Spectrom
ABSTRACT Screening of major cannabinoids in cannabis‐derived extracts is needed when these extracts are applied in pharmacological and biological studies. Precursor ion scan‐mass spectrometry (PIS‐MS) is a viable approach for the detection and screening of major cannabinoids through characteristic MS/MS fragmentation behavior.
Mahmoud R, Michel D, Elessawy F, Purves R, Laprairie R, El‐Aneed A.   +5 more
europepmc   +2 more sources

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

Δ9 Tetrahydrocannabinol and cannabis extracts differentially improve adipoinsular dysfunction in diet‐induced obesity

The Journal of Physiology, EarlyView.
Abstract figure legend THC and extract administered to diet‐induced obese mice reduced body weight and fat storage. Extract, but not THC, improved glucose clearance by a mechanism that may include restoring adipoinsular function. Abstract Diet‐induced obesity (DIO) is associated with dysregulated adipoinsular axis and endocannabinoid system (eCBS ...
Bryant Avalos, Martin Olmos, Courtney P. Wood, Camila Alvarez, Haley M. Read, Parima Udompholkul, Theodore Garland Jr, Nicholas V. DiPatrizio   +7 more
wiley   +1 more source

Medicinal cannabis approvals in Australian children and young people, 2016-2024: a national analysis of Therapeutic Goods Administration data by age, indication and cannabinoid category. [PDF]

BMJ Open
Hallinan CM, Chong HC, Norman A, Bonomo Y.   +3 more
europepmc   +1 more source

SGIP1 limits cannabinoid receptor signalling in spinal nociceptive synapses and modulates analgesia during neuroinflammation

The Journal of Physiology, EarlyView.
Abstract figure legend SGIP1 constrains presynaptic cannabinoid signalling in the spinal dorsal horn and limits cannabinoid analgesia after inflammation. In vivo (both sexes), SGIP1 KO mice showed a higher baseline heat threshold but unchanged mechanical sensitivity.
Denisa Dresslerova, Monica Pontearso, David Muzik, Anirban Bhattacharyya, Jakub Slepicka, Daniel Vasconcelos, Jiri Palecek, Diana Spicarova   +7 more
wiley   +1 more source

Cis–Trans Rotational Isomerism of Formic Acid, Sulfur, and Selenium Analogues and Their Dimers: Chemical Kinetics Under Interstellar Conditions

International Journal of Chemical Kinetics, Volume 58, Issue 12, Page 1136-1145, December 2026.
ABSTRACT We present chemical kinetic rate constants for the cis to trans isomerisation or rotamerization of monomeric seleno‐, thio‐, and formic acids and that of three of their dimeric species, based on variational transition state theory and multidimensional tunneling calculations in the gas‐phase, from 10 K to 300 K. These provide, firstly, reliable
Judith Wurmel, John M. Simmie
wiley   +1 more source

Cannabinoids in Cancer: Molecular Mechanisms of Tumor Cell Death and Translational Opportunities. [PDF]

Biomolecules
El Moghrabi AA, Al Khatib A, Cheikh IA, Al Hage C, Ismail D, Zhour M, Mwesigwa P, Darwiche N.   +7 more
europepmc   +1 more source

Maintaining IV Patency Throughout Pharmacokinetic Studies Through a Needle‐Free Blood Draw Device

Pharmacology Research &Perspectives, Volume 14, Issue 6, December 2026.
ABSTRACT Pharmacokinetic (PK) studies require temporally precise measurements of drug concentrations in biological matrices, most commonly whole blood or plasma. However, repeated venous sampling may increase participant burden and complicate PK‐intensive study designs.
William Naviaux, David Leinweber, Heather Barkholtz   +2 more
wiley   +1 more source

A transient mitochondrial switch underlies long lasting effects of adolescent cannabis. [PDF]

Neuropsychopharmacology
Ioannidou C, Manzanares-Sierra I, Jimenez-Blasco D, García-Rodriguez D, Manjarrés-Raza I, Julio-Kalajzić F, Pagano Zottola AC, Di Bartolomeo M, Ferreira G, Bolaños JP, Marsicano G, Busquets-Garcia A.   +11 more
europepmc   +1 more source