Results 91 to 100 of about 32,046 (262)
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
A Milky Way-like barred spiral galaxy at a redshift of 3. [PDF]
Nature, 2023 Costantin L +32 more
europepmc +1 more source
, 2008 In this article, I describe constructing a scale model of our galaxy—the Milky Way—and using this model to teach modern astronomy. The Milky Way model expands on concepts usually explored in the more common solar system model.
Friedman, Robert B.
core
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Mäetagused, 2002 Astronomically, the Milky Way is a big star system _ a galaxy. The word galaxy is derived from the Greek gala `milk'. In many languages the Milky Way's name is connected with milk. However, in Estonia this form of the name is rare.
Andres Kuperjanov
doaj
Farthest neighbor: the distant Milky Way satellite Eridanus II*
, 2017 We present Magellan/IMACS spectroscopy of the recently discovered Milky Way satellite Eridanus II (Eri II). We identify 28 member stars in Eri II, from which we measure a systemic radial velocity of vhel=75.6 ±1.3(stat.) ±2.0(sys.) km s-1 and a velocity ...
Kathy Romer (4460893) +1 more
core
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
The disturbed outer Milky Way disc
, 2022 The outer parts of the Milky Way's disc are significantly out of equilibrium. Using only distances and proper motions of stars from Gaia's Early Data Release 3, in the range |b| < 10°, 130° < < 230°, we show that for stars in the disc between around 10 ...
J Petersson (17650431) +11 more
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li +11 more
wiley +1 more source