Results 71 to 80 of about 32,046 (262)

4-H Group Visiting Cows at Milky Way Farms

, 1986
Young 4-H members visit the cows at Cecil Reagan's Milky Way Farms.
The Bradenton Herald
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

The Power of High-precision Broadband Photometry: Tracing the Milky Way Density Profile with Blue Horizontal Branch Stars in the Dark Energy Survey

The Astrophysical Journal
Blue horizontal branch stars (BHBs), excellent distant tracers for probing the Milky Way’s halo density profile, are distinguished in the ${\left(g-r\right)}_{0}$ versus ( i − z ) _0 color space from another class of stars, blue straggler stars.
Fengqing Yu, Ting S. Li, Joshua S. Speagle, Gustavo E. Medina, Sergey E. Koposov, Joss Bland-Hawthorn, Lara R. Cullinane, Gwendolyn M. Eadie, Denis Erkal, Geraint F. Lewis, Guilherme Limberg, Daniel B. Zucker   +11 more
doaj   +1 more source

The Milky Way and other spiral galaxies

EPJ Web of Conferences, 2012
Cosmologists have often considered the Milky Way as a typical spiral galaxy, and its properties have considerably influenced the current scheme of galaxy formation.
Wang J.L., Yang Y.B., Flores H., Puech M., Hammer F., Fouquet S.   +5 more
doaj   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

The superclouds of the local Milky Way

Astronomy & Astrophysics
Recent 3D dust maps of the local Milky Way are revolutionizing our understanding of the Sun’s Galactic neighborhood, providing much needed insight into the large-scale organization of the interstellar medium.
Kormann Lilly A., Alves João, Pantaleoni González Michelangelo, Swiggum Cameren, Enßlin Torsten A., Edenhofer Gordian   +5 more
doaj   +1 more source

Fountain-driven gas accretion by the Milky Way

EPJ Web of Conferences, 2012
Accretion of fresh gas at a rate of ∼ 1M☉yr−1 is necessary in star-forming disc galaxies, such as the Milky Way, in order to sustain their star-formation rates.
Ciotti L., Nipoti C., Binney J., Fraternali F., Marinacci F., Londrillo P.   +5 more
doaj   +1 more source

4-H Group Pets Horse at Milky Way Farms

, 1986
A group of young 4-H members pet a horse at Cecil Reagan's Milky Ways Farms.
The Bradenton Herald
core  

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source