Results 121 to 130 of about 32,046 (262)

Functional Blood‐Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino   +12 more
wiley   +1 more source

Gellan Gum Fluid Gel System for Controlled‐Delivery of Cytokine‐Licensed MSC‐EVs to Enhance Corneal Repair in Limbal Stem Cell Deficiency

open access: yesAdvanced Healthcare Materials, EarlyView.
Gellan gum fluid gel (FG) enables controlled ocular delivery of mesenchymal stromal cell (MSC)‐derived extracellular vesicles (EV). Its shear‐thinning, solid‐liquid‐solid rheology ensures prolonged ocular retention. Sustained MSC‐EV release (∼18% in 6 hrs) supports effective EV ocular delivery.
Seyedmohammad Moosavizadeh   +7 more
wiley   +1 more source

The Milky Way Stellar Halo Is Twisted and Doubly Broken: Insights from DESI DR2 Milky Way Survey Observation

open access: yesThe Astrophysical Journal
Using K giants from the second data release (DR2) of the Dark Energy Spectroscopic Instrument (DESI) Milky Way Survey, we measure the shape, orientation, radial profile, and density anisotropies of the Milky Way (MW) stellar halo over 8 kpc < r _GC < 200
Songting Li   +47 more
doaj   +1 more source

Thermally Modulated Metasurface Sensor for Dynamic and Time‐Resolved Isolation of Extracellular Vesicles

open access: yesAdvanced Materials, EarlyView.
A thermally adaptive plasmonic metasurface, functionalized with poly(N‐isopropylacrylamide) (PNIPAM) and anti‐CD63 antibodies, enables precise, on‐demand capture and release of extracellular vesicles (EVs). Delivering high recovery, improved purity, and intact vesicle structure, the platform offers a versatile, label‐free solution for real‐time EV ...
Beyza Nur Kucuk   +7 more
wiley   +1 more source

Super‐Resolution Ultrasound Based Cell Tracking With Polymeric Nanobubbles

open access: yesAdvanced Materials, EarlyView.
This study presents a super‐resolution ultrasound platform for tracking cells in vivo. Biocompatible polymeric nanobubbles are used as highly echogenic intracellular labels. Following the injection of cells and microbubbles, ultrasound localization microscopy (ULM) can dynamically match the microvascular architecture and individual cell trajectories ...
Junlin Chen   +19 more
wiley   +1 more source

The R-process Alliance: Enrichment of r-process Elements in a Simulated Milky Way–like Galaxy

open access: yesThe Astrophysical Journal
We study the formation of stars with varying amounts of heavy elements synthesized by the rapid neutron-capture process ( r -process) based on our detailed cosmological zoom-in simulation of a Milky Way–like galaxy with an N -body/smoothed particle ...
Yutaka Hirai   +13 more
doaj   +1 more source

Modelling the Milky Way in Gamma Rays for GLAST

open access: yes, 2007
The Milky Way is a bright, diffuse source of high-energy gamma rays that are produced in cosmic-ray interactions with interstellar gas and radiation. An accurate, detailed model of this emission will be important for analysis of the data from th e Large ...
Components Of The
core  

Dark Matter in the Milky Way

open access: yes, 2020
We have entered a data-driven era of astrophysics and cosmology, providing a wealth of datasets within which to search for the answers to some of the most fundamental open questions in the physics of our Universe.
Chang, Laura
core  

All‐Polyimide‐Mediated Liquid Metal Assembly on Aerogels for Breathable and Robust Electronic Skins

open access: yesAdvanced Materials, EarlyView.
An all‐polyimide‐mediated assembly strategy resolves the fundamental conflict between physiological breathability and electromechanical robustness in wearable electronics. By integrating a polyamic acid‐encapsulated liquid metal ink onto an ultralight polyimide aerogel, imidization‐induced contraction enables low‐temperature conductive activation and ...
Haijun Zhu   +18 more
wiley   +1 more source

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