Results 141 to 150 of about 134,673,186 (290)

The Structural and Kinematical Properties of NGC 5634, a Globular Cluster Associated with the Sagittarius Dwarf Galaxy?

The Astrophysical Journal
We investigate the origin of NGC 5634 through a comprehensive analysis of its morphology, kinematics, and dynamics. Utilizing data from the DESI Legacy Survey, we refined its fundamental parameters (age τ = 12.8 ± 0.3 Gyr, metallicity [Fe/H] = −1.8 ± 0.1
Shouzhi Wang, Jundan Nie, Biwei Jiang, Hao Tian, Chao Liu, Ying-Hua Zhang   +5 more
doaj   +1 more source

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

Advanced Science, EarlyView.
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li, Hao Tang, Qin Yu, Yuyang Zhang, Binglu Shi, Ying Kong, Leiyu Xu, Jingjing Shao, Chenghong Hu, Lingyu She, Zhe Wang, Haiyi Chen, Aleksandr V. Samorodov, Gang Cao, Xia Zhao, Yi Wang   +15 more
wiley   +1 more source

Chemo-dynamical Evolution of Simulated Satellites for a Milky Way–like Galaxy

The Astrophysical Journal
The chemical abundances of Milky Way’s (MW's) satellites reflect their star formation histories (SFHs), yet, due to the difficulty of determining the ages of old stars, the SFHs of most satellites are poorly measured.
Yutaka Hirai, Evan N. Kirby, Masashi Chiba, Kohei Hayashi, Borja Anguiano, Takayuki R. Saitoh, Miho N. Ishigaki, Timothy C. Beers   +7 more
doaj   +1 more source

Milky Way Dairies

, 1951
Three unidentified executives stand outside the Milky Way Building.
Douglass, Neal
core  

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

The Coherent Magnetic Field of the Milky Way

The Astrophysical Journal
We present a suite of models of the coherent magnetic field of the Galaxy based on new divergence-free parametric functions describing the global structure of the field.
Michael Unger, Glennys R. Farrar
doaj   +1 more source

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

Advanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang, Ziyao Wang, Dongyue Zuo, Zhaowen Su, Bowen Song, Jiamin Gao, Yizhou Zhang, Ruiting Zhao, Linjie Sun, Mengdi Li, Yirui Fan, Dandan Geng, Lei Wang   +12 more
wiley   +1 more source

The Low-α Splash Population in the Milky Way

The Astrophysical Journal Letters
The Milky Way metal-rich halo-like component, also known as the Splash, consists of old (age > 10 Gyr), metal-rich ([Fe/H] > −0.7), high- α stars, i.e., thick-disk-like chemistry, on halo-like orbits (eccentricity > 0.6).
Lais Borbolato, João A. S. Amarante, Hélio D. Perottoni, Silvia Rossi, Victor P. Debattista, Zhao-Yu Li, Nathan Deg, Tigran Khachaturyants   +7 more
doaj   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Milky Way Observatory

, 1998
Set-up shot for Milky Way Video Educational levels: Undergraduate lower division, Undergraduate upper division, Graduate or ...
Alex Kekesi, David Leisawitz, Edgar Russell   +2 more
core