Results 141 to 150 of about 126,794,803 (294)

The Structural and Kinematical Properties of NGC 5634, a Globular Cluster Associated with the Sagittarius Dwarf Galaxy?

open access: yesThe Astrophysical Journal
We investigate the origin of NGC 5634 through a comprehensive analysis of its morphology, kinematics, and dynamics. Utilizing data from the DESI Legacy Survey, we refined its fundamental parameters (age τ = 12.8 ± 0.3 Gyr, metallicity [Fe/H] = −1.8 ± 0.1
Shouzhi Wang   +5 more
doaj   +1 more source

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao   +10 more
wiley   +1 more source

The Coherent Magnetic Field of the Milky Way

open access: yesThe Astrophysical Journal
We present a suite of models of the coherent magnetic field of the Galaxy based on new divergence-free parametric functions describing the global structure of the field.
Michael Unger, Glennys R. Farrar
doaj   +1 more source

An Engineered Biomimetic Nanoreactor With Cascade Functions for Targeted and Combinatorial Therapy of Ischemic Stroke

open access: yesAdvanced Healthcare Materials, EarlyView.
Preparation of RVG‐modified erythrocyte membrane‐coated HMPB nanocarriers loaded with L‐arginine and NBP (RM@HPAN) and its neuroprotective mechanism. After intravenous injection, RM@HPAN achieves prolonged circulation, RVG‐29‐mediated BBB penetration, and ischemic accumulation.
Shaofa Li   +9 more
wiley   +1 more source

Chemo-dynamical Evolution of Simulated Satellites for a Milky Way–like Galaxy

open access: yesThe Astrophysical Journal
The chemical abundances of Milky Way’s (MW's) satellites reflect their star formation histories (SFHs), yet, due to the difficulty of determining the ages of old stars, the SFHs of most satellites are poorly measured.
Yutaka Hirai   +7 more
doaj   +1 more source

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

open access: yesAdvanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song   +14 more
wiley   +1 more source

The Low-α Splash Population in the Milky Way

open access: yesThe Astrophysical Journal Letters
The Milky Way metal-rich halo-like component, also known as the Splash, consists of old (age > 10 Gyr), metal-rich ([Fe/H] > −0.7), high- α stars, i.e., thick-disk-like chemistry, on halo-like orbits (eccentricity > 0.6).
Lais Borbolato   +7 more
doaj   +1 more source

Transient Cytoskeletal Anisotropy Encodes Short‐Term Mechanical Memory in Glioblastoma Cells

open access: yesAdvanced Materials, EarlyView.
The same mechanical deformation can produce distinct cytoskeletal states depending on loading history. Experiments and constitutive modeling reveal that transient actin–vimentin anisotropy stores mechanical information and governs short‐term mechanical memory in glioblastoma cells.
Clara Gomez‐Cruz   +5 more
wiley   +1 more source

Observational Signatures of AGN Feedback in the Morphology and the Ionization States of Milky Way-like Galaxies

open access: yesThe Astrophysical Journal
We make an in-depth analysis of different active galactic nuclei (AGN) jet models’ signatures, inducing quiescence in galaxies with a halo mass of 10 ^12 M _⊙ .
Nadia Qutob   +26 more
doaj   +1 more source

Polyphenol‐Inspired Materials for Agricultural Applications

open access: yesAdvanced Materials, EarlyView.
This review outlines the use of polyphenol‐inspired materials for sustainable agriculture, highlighting their molecular design, interfacial assembly, structure–property relationships, and prospects toward precision agriculture, climate resilience, ecosystem protection, and circular bioeconomy strategies.
Haofu Liu   +8 more
wiley   +1 more source

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