Results 31 to 40 of about 126,794,803 (294)

The normativity of rationality [PDF]

open access: yes, 2010
This article is an introduction to the recent debate about whether rationality is normative – that is, very roughly, about whether we should have attitudes which fit together in a coherent way.
Way, Jonathan, Jonathan Way
core   +1 more source

The Rapid Formation of the Metal-poor Milky Way

open access: yesThe Astrophysical Journal
Our understanding of the assembly timeline of the Milky Way has been transforming along with the dramatic increase in astrometric and spectroscopic data available over the past several years.
Rebecca Woody   +8 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

SF-R You Sure? The Conflicting Role of Star Formation Rates in Constraining the Evolution of Milky Way Analogs in Cosmological Simulations

open access: yesThe Astrophysical Journal
Milky Way analogs (MWAs) have long been studied by astronomers to place our Galaxy within an extragalactic context. With the power of cosmological simulations, we are now able to not only characterize MWAs today, but also watch as they evolve through ...
Alicia M. Savelli   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Illustrations from The Turing Way: Shared under CC-BY 4.0 for reuse

open access: yes, 2022
Illustrations created by Scriberia as part of the Turing Way book dashes and illustration sprints in 2019 (two events in person), 2020 (one event in-person and one online), 2021 (two online), 2022 (Turing-Crick partnership project hybrid sprint, one Book
The Turing Way Community, Scriberia
core   +1 more source

Minimum-entropy Constraints on Galactic Potentials

open access: yesThe Astrophysical Journal
A tracer sample in a gravitational potential, starting from a generic initial condition, phase-mixes toward a stationary state. This evolution is accompanied by an entropy increase, and the final state is characterized by a distribution function (DF ...
Leandro Beraldo e Silva   +5 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

The Mass of the Milky Way Galaxy [PDF]

open access: yes, 2023
On the Basis of tabular values of the gravitational constant. The calculated mass of the nucleus of the milky way galaxy. The numerical value of the gravitational constant is determined by the mass of the nucleus of the milky way galaxy.
Shavkyatovich, Yanbikov Vildan
core  

Synthetic Gaia DR3 Surveys from the FIRE Cosmological Simulations of Milky Way-mass Galaxies

open access: yesThe Astrophysical Journal
The third data release (DR3) of Gaia has provided a fivefold increase in the number of radial velocity measurements of stars, as well as a stark improvement in parallax and proper motion measurements.
Tri Nguyen   +6 more
doaj   +1 more source

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