Results 31 to 40 of about 32,046 (262)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Estimating the Initial Mass of the Gaia–Enceladus Dwarf Galaxy with a Chemical Evolution Model
The Astrophysical JournalThis work investigates the initial mass and chemical evolution history of the Gaia–Enceladus dwarf galaxy. We combine spectroscopic data from APOGEE with astrometric data from Gaia Data Release 3 to identify Gaia–Enceladus candidate stars via a machine ...
Olcay Plevne, Furkan Akbaba
doaj +1 more source
Simulating the Milky Way is hard
EPJ Web of Conferences, 2012 The formation of the Milky Way in the currently accepted concordance cosmology presents a couple of pitfalls. Mostly, these involve the much reported overcooling problem.
Stinson G., Brook C.
doaj +1 more source
Stellar abundances in clusters: High-resolution, multi-object spectroscopy of globular & open clusters in the Milky Way [PDF]
, 2015 Talk on high-resolution, multi-object spectroscopy of globular & open clusters in the Milky ...
BRAGAGLIA, Angela
core
, 2012 We briefly describe TRILEGAL, a TRIdimensional modeL of thE GALaxy, and its more recent developments. Particularly relevant is the recent inclusion of a kinematical module to the code, and the present efforts to provide a more solid calibration of Milky ...
Barbieri, Mauro +8 more
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
What Is Missing from the Local Stellar Halo?
The Astrophysical JournalThe Milky Way’s stellar halo, which extends to >100 kpc, encodes the evolutionary history of our Galaxy. However, most studies of the halo to date have been limited to within a few kiloparsecs of the Sun.
Katherine Sharpe +2 more
doaj +1 more source
Rotation curve of the Milky Way
EPJ Web of Conferences, 2012 We use SEGUE and Hipparcos data to restrict the behaviour of the rotation curve of the Milky Way in the solar neighbourhood. Then we construct a density model of the Milky Way which best reproduces the available observations of the rotation curve and is ...
Lee Y.S. +3 more
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
The Astrophysical JournalUnder the assumption of a simple and time-invariant gravitational potential, many Galactic dynamics techniques infer the milky Way’s mass and dark matter distributions from stellar kinematic observations.
Danny Horta +7 more
doaj +1 more source