Results 41 to 50 of about 126,794,803 (294)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Estimating the Initial Mass of the Gaia–Enceladus Dwarf Galaxy with a Chemical Evolution Model
The Astrophysical JournalThis work investigates the initial mass and chemical evolution history of the Gaia–Enceladus dwarf galaxy. We combine spectroscopic data from APOGEE with astrometric data from Gaia Data Release 3 to identify Gaia–Enceladus candidate stars via a machine ...
Olcay Plevne, Furkan Akbaba
doaj +1 more source
Simulating the Milky Way is hard
EPJ Web of Conferences, 2012 The formation of the Milky Way in the currently accepted concordance cosmology presents a couple of pitfalls. Mostly, these involve the much reported overcooling problem.
Stinson G., Brook C.
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
What Is Missing from the Local Stellar Halo?
The Astrophysical JournalThe Milky Way’s stellar halo, which extends to >100 kpc, encodes the evolutionary history of our Galaxy. However, most studies of the halo to date have been limited to within a few kiloparsecs of the Sun.
Katherine Sharpe +2 more
doaj +1 more source
Rotation curve of the Milky Way
EPJ Web of Conferences, 2012 We use SEGUE and Hipparcos data to restrict the behaviour of the rotation curve of the Milky Way in the solar neighbourhood. Then we construct a density model of the Milky Way which best reproduces the available observations of the rotation curve and is ...
Lee Y.S. +3 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Stellar abundances in clusters: High-resolution, multi-object spectroscopy of globular & open clusters in the Milky Way [PDF]
, 2015 Talk on high-resolution, multi-object spectroscopy of globular & open clusters in the Milky ...
BRAGAGLIA, Angela
core
Planetary nebulae beyond the milky way - Historical overview [PDF]
, 2006 Up to 10% of the total luminosity of a planetary nebula, ~500 L⊙, can be emitted in the dominant cooling line, [O iii] λ5007. This, coupled with the narrowness of the line (~15-25 km s-1), makes it extremely easy to detect PNe in external galaxies using ...
Barlow, MJ
core +1 more source
The Astrophysical JournalUnder the assumption of a simple and time-invariant gravitational potential, many Galactic dynamics techniques infer the milky Way’s mass and dark matter distributions from stellar kinematic observations.
Danny Horta +7 more
doaj +1 more source