Results 81 to 90 of about 173,239 (326)

The Milky Way bulge

This chapter reviews the three-dimensional structure, age, kinematics, and chemistry of the Milky Way (MW) region within ~2 kpc from its center (hereafter referred to as the 'bulge') from an observational perspective. While not exhaustive in citations, this review provides historical context and discusses the main controversies and limitations in the ...
Zoccali, Manuela, Valenti, Elena
openaire   +2 more sources

HI shells in the outer Milky Way

, 2005
We present results of a method for an automatic search for HI shells in 3D data cubes and apply it to the Leiden-Dwingeloo HI survey of the northern Milky Way.
Ehlerova, S., Palous, J.
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

What Is Missing from the Local Stellar Halo?

The Astrophysical Journal
The Milky Way’s stellar halo, which extends to >100 kpc, encodes the evolutionary history of our Galaxy. However, most studies of the halo to date have been limited to within a few kiloparsecs of the Sun.
Katherine Sharpe, Rohan P. Naidu, Charlie Conroy   +2 more
doaj   +1 more source

Rotation curve of the Milky Way

EPJ Web of Conferences, 2012
We use SEGUE and Hipparcos data to restrict the behaviour of the rotation curve of the Milky Way in the solar neighbourhood. Then we construct a density model of the Milky Way which best reproduces the available observations of the rotation curve and is ...
Lee Y.S., Beers T.C., Just A., Golubov O.   +3 more
doaj   +1 more source

The Chemical Evolution of the Milky Way

, 1999
The field of chemical evolution modeling of the Galaxy is experiencing in the last years a phase of high activity and important achievements. There are, however, several open questions which still need to be answered. In this review I summarize what have
A Pasquali, A Renzini, AA Penzias, AI Boothroyd, B Barbuy, B Edvardsson, C Chiappini, CG Lacey, E Anders, F Matteucci, Forestini, JM Scalo, LB van den Hoek, M Tosi, M Tosi, M Tosi, M Tosi, N Prantzos, P Kroupa, PA Shaver, R Wielen, Rocha, S Boissier, S Smartt, SE Woosley, T.C. Beers, WJ Maciel, WJ Maciel   +27 more
core   +1 more source

Geometry-driven and dark-matter-sustained Milky Way rotation curves with Gaia DR3

Monthly notices of the Royal Astronomical Society
Thanks to Gaia DR2, we proved for the first time that a general relativistic Milky Way rotation curve is statistically indistinguishable from its state-of-the-art dark matter analogue.
William Beordo, M. Crosta, M. Lattanzi, P. Re Fiorentin, A. Spagna   +4 more
semanticscholar   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Orbital Torus Imaging: Acceleration, Density, and Dark Matter in the Galactic Disk Measured with Element Abundance Gradients

The Astrophysical Journal
Under the assumption of a simple and time-invariant gravitational potential, many Galactic dynamics techniques infer the milky Way’s mass and dark matter distributions from stellar kinematic observations.
Danny Horta, Adrian M. Price-Whelan, David W. Hogg, Kathryn V. Johnston, Lawrence Widrow, Julianne J. Dalcanton, Melissa K. Ness, Jason A. S. Hunt   +7 more
doaj   +1 more source

The Dark Disk of the Milky Way

, 2009
Massive satellite accretions onto early galactic disks can lead to the deposition of dark matter in disk-like configurations that co-rotate with the galaxy. This phenomenon has potentially dramatic consequences for dark matter detection experiments.
Bruch, Chris W. Purcell, Conroy, Gilmore, Gomez, Hammer, James S. Bullock, Jurić, Kazantzidis, Manoj Kaplinghat, Moster, Purcell, Purcell, Stewart, Widrow, Wyse   +15 more
core   +1 more source