Results 151 to 160 of about 3,556 (301)

Erratum to: Results from the search for dark matter in the Milky Way with 9 years of data of the ANTARES neutrino telescope? (Physics Letters B (2017) 769 (249?254), (S037026931730254X), (10.1016/j.physletb.2017.03.063))

open access: yes, 2019
Limits on the neutrino flux for a given mass [Formula presented] and annihilation channel are calculated as in Eq. (7) (page 252), with the integrated acceptances defined in Eq. (8) (page 252) as the effective area averaged over the neutrino energy. A numerical approximation of WIMP annihilation spectra, adapted from [1] with a too coarse binning, led ...
Albert A.   +128 more
openaire   +5 more sources

Inhibition of Focal Adhesion Restricts Chemoresistance in Pancreatic Cancer by Targeting SLC7A11 Mediated Ferroptosis

open access: yesAdvanced Science, EarlyView.
FAK signaling drives chemoresistance and tumor evolution in pancreatic ductal adenocarcinoma. The FAK inhibitor IN10018 restores gemcitabine sensitivity by inducing SLC7A11‐mediated ferroptosis through the PI3K‐Akt pathway and remodeling the tumor microenvironment, reducing mesenchymal components while enhancing CD8+ T‐cell infiltration in preclinical ...
Yingjin Wang   +11 more
wiley   +1 more source

The AIDA-TNG project: Dark matter profiles and concentrations in alternative dark matter models

open access: yesAstronomy & Astrophysics
In the standard cold dark matter (CDM) scenario, the density profiles of dark matter haloes are well described by analytical models linking their concentration to halo mass.
Despali Giulia   +5 more
doaj   +1 more source

The Chemistry of the Milky Way: From Micro- to Macro-Physics

open access: yes
The Chemistry of the Milky Way: From Micro- to Macro-Physics. The physics of galaxy formation in the early Universe is driving the development of billion-dollar investments such as the Next Generation Space Telescope and the Square Kilometre Array.

core  

Incorrect rotation curve of the Milky Way

open access: yes, 2015
International audienceIn the fundamental quest of the rotation curve of the Milky Way, the tangent-point method has long been the simplest way to infer velocities for the inner low-latitude regions of the Galactic disk from observations of the gas ...
Renaud, Florent,   +5 more
core   +1 more source

Aptamer‐Directed Porous DNA Nanocomposite Hydrogel for Active Pulp Preservation: Immunomodulation, Stem Cell Recruitment and Reparative Dentinogenesis

open access: yesAdvanced Science, EarlyView.
This study presents an injectable DNA‐based porous hydrogel integrating catechol motifs and targeting aptamers for pulpitis management. Upon in situ crosslinking, the scaffold actively recruits endogenous dental pulp stem cells, restores redox homeostasis, and modulates immune responses.
Luhui Cai   +9 more
wiley   +1 more source

The Three-mm Ultimate Mopra Milky Way Survey. III. Data Release 6, An Atlas of Physical Conditions, Global Mass Conversion Laws, and 3D Physical Architecture of the Molecular ISM in the Fourth Quadrant

open access: yes
Replaced with accepted version for ApJS, after modest revisions. Main paper 16 pages, 11 figures. Appendix A 15 pages, 11 figures. Appendix B 11 pages, 10 figures.
Barnes, Peter J.   +4 more
openaire   +2 more sources

3.55 keV photon lines from axion to photon conversion in the Milky Way and M31

open access: yes, 2014
We further explore a scenario in which the recently observed 3.55 keV photon line arises from dark matter decay to an axion-like particle (ALP) of energy 3.55 keV, which then converts to a photon in astrophysical magnetic fields.
Conlon, JP, Day, Francesca, Day, FV
core   +1 more source

Drug‐Induced Cuproptosis Defines the Therapeutic Window of Celecoxib in Intervertebral Disc Degeneration via the HSP90‐RBX1 Axis

open access: yesAdvanced Science, EarlyView.
This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo   +11 more
wiley   +1 more source

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