Results 61 to 70 of about 3,077,511 (309)

The personality systems framework: Current theory and development [PDF]

open access: yes, 2015
The personality systems framework is a fieldwide outline for organizing the contemporary science of personality. I examine the theoretical impact of systems thinking on the discipline and, drawing on ideas from general systems theory, argue that ...
Mayer, John D.
core   +2 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

On the morals-centeredness of Kant’s transcendental anthropology and on the role of morals in the human nature [PDF]

open access: yesКантовский сборник, 2010
This article proves that the philosophical system of Kant is a system of transcendental anthropology, which acts a method in Kant’s pragmatic anthropology. The essence of transcendental anthropology is the metaphysics of morals.
Kalinnikov L. A.
doaj   +1 more source

Reasons and Theoretical Rationality [PDF]

open access: yes, 2018
This chapter explores the relationship between reasons and epistemic rationality. In recent debates about rationality and evidence, internalist evidentialism is quite popular. Using this theory as our stalking horse, we examine debates about the ontology of evidence and reasons, a puzzle about rationality and evidential support relations, work on the ...
openaire   +1 more source

Living as if God exists: Looking for Common Ground in Times of Radical Pluralism [PDF]

open access: yes, 2014
This paper offers some comments on some metaphysical and epistemological claims of theological realism from the perspective of continental philosophy of religion, thereby taking the work of Soskice and Hick as paradigmatic for this kind of philosophical ...
Jonkers, Peter
core   +2 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Deduction of Freedom vs Deduction of Experience in Kant’s Metaphysics

open access: yesКантовский сборник, 2019
My aim is to demonstrate the specificities and differences between transcendental deduction of concepts and deduction of the fundamental principles of pure practical reason in Kant’s metaphysics.
Semyonov V.E
doaj   +1 more source

On the moralcentrism of Kant's transcendental anthropology and the role of morals in human nature (continuation) [PDF]

open access: yesКантовский сборник, 2011
This article proves that Kant's philosophical system is a system of transcendental anthropology, which acts as a method in Kant’s pragmatic anthropology. The essence of transcendental anthropology is the metaphysics of morals.
Kalinnikov L. A.
doaj   +1 more source

The correlation length of the Heisenberg antiferromagnet with arbitrary spin S

open access: yes, 1999
Experiments and numerical data on the correlation length for large S disagree strongly with the theoretical prediction based on the effective field theory prescription of the magnon physics.
Hasenfratz, P.
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

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