Results 91 to 100 of about 2,758,604 (298)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Theory and Practice of the Public Sector Savings: The Case of Czech Regions
Transylvanian Review of Administrative Sciences, 2014 In recent years, the necessity to allocate resources in economically rational ways has been amplified in the context of budget austerity measures and the overall tendency for balanced public budgets. Under these long-term circumstances, political leaders
Milan PŮČEK, František OCHRANA
doaj
On the Hamilton's isoperimetric ratio in complete Riemannian manifolds of finite volume
, 2020 We contribute to an original problem studied by Hamilton and others, in order to understand the behaviour of maximal solutions of the Ricci flow both in compact and non-compact complete orientable Riemannian manifolds of finite volume.
Nardulli, Stefano, Russo, Francesco G.
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Interstellar Turbulence II: Implications and Effects
, 2004 Interstellar turbulence has implications for the dispersal and mixing of the elements, cloud chemistry, cosmic ray scattering, and radio wave propagation through the ionized medium.
Achterberg A +54 more
core +2 more sources
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Introduction: Regions of Memory in Theory
, 2022 AbstractSetting the agenda for the chapters to come, the volume editors lay out in this chapter the importance of moving beyond the nation state in memory studies, arguing that a narrower and more specific framework than the global/universal needs to be developed.
Simon Lewis, Joanna Wawrzyniak
openaire +1 more source
Statistical problem of ideal gas in general 2-dimensional regions
, 2014 In this paper, based on the conformal mapping method and the perturbation theory, we develop a method to solve the statistical problem within general 2-dimensional regions. We consider some examples and the numerical results and fitting results are given.
Li, Wen-Du +3 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Theory and methodology in predicting the religious tourism in Buddhist regions of Russia
Новые исследования Тувы, 2015 Article reviews the theoretical and methodological aspects of forecasting the touristic migrations. The theoretical approach is designed according to the anthropological theory of cultural exchange, tourism forecasting methodology developed by the author
Petr E. Tsarkov
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