Results 71 to 80 of about 2,758,604 (298)

REGIONAL COMPETITIVENESS OF REGIONS (CONCEPT - PILLARS - STRATEGIES AND THEORIES) [PDF]

Journal of Al-Azhar University Engineering Sector, 2019
The regional competitiveness aims to achieve balanced growth in line with theresources available in the region, as it means: the ability of the region to exploit all theresources and components existing in the region to optimize utilization, to provide anenvironment conducive to development activities, with the aim of achieving a betterstandard of ...
Hassanein Abu Zaid, Bakr Bayoumy, Reda Abdel Hamid, Zaghloul Al-Saidi, Mohammed Shukry   +4 more
openaire   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Regional Income Disparities in Canada: Implications for Theories of Regional Convergence [PDF]

Review of Regional Studies, 1996
Traditional regional convergence theory has come under serious scrutiny in view of the recent divergence in regional incomes in the U.S. during the eighties. Neither the neoclassical theory of a steady decline in regional disparities over time nor Kuznets’ inverted-U hypothesis can satisfactorily explain regional divergence in an advanced industrial ...
Elias G. Carayannis, Rajiv Mallick
openaire   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Are all beliefs equal? Implicit belief attributions recruiting core brain regions of theory of mind.

PLoS ONE, 2014
Humans possess efficient mechanisms to behave adaptively in social contexts. They ascribe goals and beliefs to others and use these for behavioural predictions. Researchers argued for two separate mental attribution systems: an implicit and automatic one
Agnes Melinda Kovács, Simone Kühn, György Gergely, Gergely Csibra, Marcel Brass   +4 more
doaj   +1 more source

On the Complementarity of F-theory, Orientifolds, and Heterotic Strings [PDF]

, 1998
We study F-theory duals of six dimensional heterotic vacua in extreme regions of moduli space where the heterotic string is very strongly coupled. We demonstrate how to use orientifold limits of these F-theory duals to regain a perturbative string ...
Aspinwall, Aspinwall, Berkooz, Bershadsky, Bershadsky, Bianchi, Bianchi, Blum, Blum, Candelas, Dabholkar, Dabholkar, Duff, Duff, Eguchi, Eric Gimon, Ferrara, Ganor, Gibbons, Gimon, Gimon, Gimon, Gopakumar, Horava, Hull, Louis, Morrison, Morrison, Per Berglund, Polchinski, Polchinski, Romans, Sagnotti, Schwarz, Seiberg, Sen, Sen, Sen, Sen, Strominger, Vafa, Witten, Witten   +42 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Cosmological correlators in massless ϕ 4-theory and the method of regions

Journal of High Energy Physics
The calculation of loop corrections to the correlation functions of quantum fields during inflation or in the de Sitter background presents greater challenges than in flat space due to the more complicated form of the mode functions.
Martin Beneke, Patrick Hager, Andrea F. Sanfilippo   +2 more
doaj   +1 more source

Socio-Economic Status of Russia’s Median Region

Prostranstvennaâ Èkonomika, 2005
Theoretical conclusions have been made as to the character and key features of a region’s «median position» and their influence on the main objectives and tendencies in managing the development of such regions.
Alexander Ivanovich Tatarkin
doaj   +1 more source

On asymptotic dark energy in string theory

Journal of High Energy Physics, 2023
We examine bounds on accelerated expansion in asymptotic regions of the moduli space in string theory compactifications to four spacetime dimensions. While there are conjectures that forbid or constrain accelerated expansion in such asymptotic regions ...
Sera Cremonini, Eduardo Gonzalo, Muthusamy Rajaguru, Yuezhang Tang, Timm Wrase   +4 more
doaj   +1 more source