Results 81 to 90 of about 512,183 (308)

A model of the Keynesian theory for Portugal. Another approach [PDF]

open access: yes
With this work we try to present an alternative model for Portugal based on the Keynesian theory. We built the model testing the validity of the well known “Verdoorn´s Law” which considers the relationship between the growth of productivity and output in
Martinho, Vítor João Pereira Domingues
core   +1 more source

Theory and Practice of the Public Sector Savings: The Case of Czech Regions

open access: yesTransylvanian Review of Administrative Sciences, 2014
In recent years, the necessity to allocate resources in economically rational ways has been amplified in the context of budget austerity measures and the overall tendency for balanced public budgets. Under these long-term circumstances, political leaders
Milan PŮČEK, František OCHRANA
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

The Role of Structural Funds in Developing Learning Regions [PDF]

open access: yes
The thematic background of learning regions is based on the concept of learning organisations and on the paradigm of the innovative milieu. The frame of reference of the learning regions can be seen as a synthesis of regional and organisational based ...
Jari Ritsilä, Jukka Haukka
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Higher-order fermion interactions in effective field theories for phase transitions

open access: yesPhysics Letters B
We investigate the impact of higher-order fermionic deformations in phase transitions analogous to those described by the Bardeen-Cooper-Schrieffer (BCS) theory.
D. Rodriguez-Gomez, J.G. Russo
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Efficient Calculations of Molecular Linear Response Properties for Spectral Regions [PDF]

open access: yes, 2014
Molecular spectra can be determined from molecular response functions, by solving the so-called damped response equations using the complex polarization propagator approach.
Kauczor, Joanna,, Norman, Patrick,
core   +1 more source

Theory and methodology in predicting the religious tourism in Buddhist regions of Russia

open access: yesНовые исследования Тувы, 2015
Article reviews the theoretical and methodological aspects of forecasting the touristic migrations. The theoretical approach is designed according to the anthropological theory of cultural exchange, tourism forecasting methodology developed by the author
Petr E. Tsarkov
doaj  

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