Results 131 to 140 of about 12,371 (307)
Molecular Oncology, EarlyView.Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li +12 more
wiley +1 more source
Lo spazio-tempo nei viaggi medievali nell'aldilà
Études romanes de Brno, 2009 Medieval descriptions of journeys to the Other World often contain a temporal distortion which their protagonists experience personally; the movement in the space lead them to cross a temporal border also, so that their return to the earthly space does ...
Massimo Bonafin
doaj
A paralel transport along a light ray in the space-time of the theory of relativity [PDF]
, 1928 Václav Hlavatý
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Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
Molecular Oncology, EarlyView.In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza +3 more
wiley +1 more source
Note on the central differential equation in the relativity theory of gravitation
, 1920 Andrew Russell Forsyth
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Molecular Oncology, EarlyView.Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
Molecular Oncology, EarlyView.RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source
Non-conjectural theory of relativity as a non-holonomic Laguerre geometry realized in the three-dimensionaltorsioned Cartesian space fibered with actions [PDF]
, 1955 Tsurusaburo Takasu
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