Results 11 to 20 of about 18,121,732 (293)
International Journal of Molecular Sciences, 2022 Neurodegenerative disorders are primarily characterized by neuron loss. The most common neurodegenerative disorders include Alzheimer’s and Parkinson’s disease.
R. Lamptey +5 more
semanticscholar +1 more source
Synthetic thiophenes induce chromosomal damage and trigger apoptosis in human cancer cell lines
European Journal of Medicinal Chemistry Reports, 2022 Thiophenes are heterocyclic compounds containing a five-membered ring with sulphur as the heteroatom. This class of substances has been shown to have several biological activities, including specific anti-proliferative effects against some cancer cell ...
Filipe N. Franco +10 more
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Advances in Diagnostic Tools and Therapeutic Approaches for Gliomas: A Comprehensive Review
Italian National Conference on Sensors, 2023 Gliomas, a prevalent category of primary malignant brain tumors, pose formidable clinical challenges due to their invasive nature and limited treatment options.
Gayathree Thenuwara +2 more
semanticscholar +1 more source
Excessive daytime sleepiness in adolescents: current treatment strategies [PDF]
Sleep Science, 2020 The complaints of excessive daytime sleepiness are very common among adolescents. In addition, in this particular subpopulation, the presence of excessive daytime sleepiness is associated with negative impact on school ...
Matthieu Hein +3 more
doaj +1 more source
Antioxidants, 2023 This review reports in detail the cellular and molecular mechanisms which regulate the bone remodeling process in relation to oxidative stress (OS), inflammatory factors, and estrogen deficiency.
G. Marcucci +5 more
semanticscholar +1 more source
Galectins as pivotal components in oncogenesis and immune exclusion in human malignancies
Frontiers in Immunology, 2023 Galectins are galactoside-binding proteins, exerting numerous functions inside and outside the cell, particularly conferring adaptation to stress factors. For most of them, aberrant expression profiles have been reported in the context of cancer.
Nikiforos-Ioannis Kapetanakis +1 more
doaj +1 more source
International Journal of Molecular Sciences, 2022 Pulmonary fibrosis is a chronic progressive lung disease that steadily leads to lung architecture disruption and respiratory failure. The development of pulmonary fibrosis is mostly the result of previous acute lung inflammation, caused by a wide variety
I. Savin, M. Zenkova, A. Sen’kova
semanticscholar +1 more source
Translational Oncology, 2022 Highlights • Tobacco consumption and infection with high-risk human papillomavirus (HPV) are the major risk factors of the Head and neck squamous cell carcinoma (HNSCC).• In current clinical trials the three main therapeutic approaches being employed for
Bharat Goel +7 more
semanticscholar +1 more source
YAP/TAZ as master regulators in cancer – modulation, function and therapeutic approaches
Nature Cancer, 2022 Our understanding of the function of the transcriptional regulators YAP and TAZ (YAP/TAZ) in cancer is advancing. In this Review, we provide an update on recent progress in YAP/TAZ biology, their regulation by Hippo signaling and mechanotransduction and ...
S. Piccolo +3 more
semanticscholar +1 more source
Recent Strategies to Combat Biofilms Using Antimicrobial Agents and Therapeutic Approaches
Pathogens, 2022 Biofilms are intricate bacterial assemblages that attach to diverse surfaces using an extracellular polymeric substance that protects them from the host immune system and conventional antibiotics. Biofilms cause chronic infections that result in millions
Looniva Shrestha +3 more
semanticscholar +1 more source